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                    [post_date] => 2024-08-14 10:27:13
                    [post_date_gmt] => 2024-08-14 14:27:13
                    [post_content] => 

The XplorIR Quantification Package provides hazmat responders with the capability to not only identify thousands of gases and vapors, but also quantify them in real-time on scene. This represents the only device of it's kind which can accurately detect, identify, and quantify, thousands of gases in seconds. With this unmatched capability, responders are able to respond swiftly to assess atmospheric conditions and make rapid decisions on PPE selection, exposure potential, mitigation techniques, and influence tactical considerations.

[post_title] => XplorIR Quantification [post_excerpt] => Read this application note to learn about XplorIR quantification package which allows users to measure the concentration of a hazardous gas or vapor and part-per-million (ppm) levels. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => xplorir-quantification [to_ping] => [pinged] => [post_modified] => 2024-08-14 10:27:14 [post_modified_gmt] => 2024-08-14 14:27:14 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25576 [menu_order] => 11 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 24672 [post_author] => 36 [post_date] => 2024-06-14 09:24:15 [post_date_gmt] => 2024-06-14 13:24:15 [post_content] =>

Responders to hazardous materials incidents face significant risks from flammable atmospheres. To manage this threat, teams use structural firefighting gear, SCBA, and various sensors, including LEL sensors, for initial reconnaissance and subsequent entries. However, traditional Catalytic Bead LEL sensors can be inaccurate due to calibration issues with different gases and a limited scope, creating more safety risk. The XplorIR® device  allows responders to identify the specific gas or vapor detected. This enables real-time adjustments to the sensor readings, improving safety by reducing the need for action levels, speeding up leak identification, and enhancing overall mitigation efforts.

[post_title] => XplorIR and LEL Sensors for Hazmat Response [post_excerpt] => Learn about the integration of XplorIR's gas identification capabilities with the common air monitoring tool of the LEL sensor. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => xplorir-and-lel-sensors-for-hazmat-response [to_ping] => [pinged] => [post_modified] => 2024-11-01 15:14:45 [post_modified_gmt] => 2024-11-01 19:14:45 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24672 [menu_order] => 12 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 24670 [post_author] => 29 [post_date] => 2024-06-14 09:24:16 [post_date_gmt] => 2024-06-14 13:24:16 [post_content] =>

Colorimetric tubes have been a standard in the downrange toolkits of many first responders. Despite their widespread use, they are plagued by high error rates, significant cross-sensitivities, and an inability to conduct continuous gas monitoring. The XplorIR significantly reduces the reliance on individual colorimetric tubes. The XplorIR is the only FTIR analyzer that can provide continuous gas monitoring at operationally relevant concentrations while uniquely identifying over 5600 chemicals and up to 6 components simultaneously within a gas mixture.

[post_title] => Are Colorimetric Tubes Becoming Obsolete for HazMat/CBRN Response [post_excerpt] => Learn how the XplorIR revolutionizes gas detection by eliminating the drawbacks of traditional colorimetric tubes. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => are-colorimetric-tubes-obsolete-hazmat [to_ping] => [pinged] => [post_modified] => 2024-07-29 09:43:02 [post_modified_gmt] => 2024-07-29 13:43:02 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24670 [menu_order] => 31 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 24641 [post_author] => 36 [post_date] => 2024-06-14 09:24:16 [post_date_gmt] => 2024-06-14 13:24:16 [post_content] =>

In emergency response, 4-gas or 5-gas air monitors with oxygen sensors ensure sufficient O2 levels for both responder safety and proper function of Catalytic Bead LEL sensors. However, a drop in O2 below 19.5% is considered IDLH by OSHA, signaling the need for supplied air respirators. Even a small decrease in O2 can indicate a large presence of contaminants, as a 0.1% drop in O2 can represent around 5,000 ppm of an unknown substance. If the XplorIR® device is used with these monitors, it can detect contaminants at much lower levels (25-50 ppm) compared to the O2 sensor, enhancing safety and reducing the risk of exposure to potentially dangerous gas clouds. XplorIR'[SW1] s capability to identify over 5,600 gases and vapors at levels well under the detection ability of O2 sensors provides an added layer of safety during reconnaissance operations.


 [SW1]only need registered mark on the first mention of product.

[post_title] => XplorIR Solves Oxygen Displacement for Hazmat Response [post_excerpt] => Learn how XplorIR identifies contaminants lower than an O2 sensor, and why it is deployed with gas monitors during recon entry. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => o2-displacement-and-xplorir [to_ping] => [pinged] => [post_modified] => 2024-11-01 15:21:27 [post_modified_gmt] => 2024-11-01 19:21:27 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24641 [menu_order] => 32 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 25898 [post_author] => 15 [post_date] => 2024-09-10 15:24:09 [post_date_gmt] => 2024-09-10 19:24:09 [post_content] =>

In this application note, by using a combination of analytical tools including REBEL and MAVEN, we were able to gain unique insights that allowed us to perform a data-driven optimization of a bioprocess and reach the process development goals with regards to titer, toxic metabolite profiles, and viability. REBEL, an amino acid analyzer streamlines bioprocess optimization by providing rapid, at-line spent-media analysis. It helps optimize nutrient feeding, control toxic metabolites, and improve cell viability, resulting in higher yields, including a 30% titer increase in one case.

[post_title] => Data-driven CHO Bioprocess Optimization and Scale-up with At-line Intelligence of Key Media Components [post_excerpt] => Accelerate your process development with the fast, at-line REBEL analyzer, which provides amino acid analysis in minutes. Rapid analysis minimizes the time between bioprocess development experiments, helping you optimize nutrient feeding and control toxic metabolite production. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => data-driven-cho-bioprocess-optimization-and-scale-up-with-at-line-intelligence-of-key-media-components [to_ping] => [pinged] => [post_modified] => 2024-09-10 15:24:53 [post_modified_gmt] => 2024-09-10 19:24:53 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25898 [menu_order] => 33 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [5] => WP_Post Object ( [ID] => 24637 [post_author] => 36 [post_date] => 2024-06-14 09:24:16 [post_date_gmt] => 2024-06-14 13:24:16 [post_content] =>

Learn how XplorIR accurately identifies toxic gases that can give your air monitors false readings or inhibit accurate measurements.

Carbon monoxide (CO) electrochemical sensors, commonly used in 4 or 5-gas air monitors, can give inaccurate readings due to cross-sensitivity with other gases and vapors. Inexperienced operators may incorrectly assume that any CO reading indicates the presence of CO, which can be dangerous.. XplorIR® can complement CO sensors by identifying not only CO but also many of these cross-sensitive gases, improving the accuracy of readings and enhancing responder safety. This pairing ensures a more reliable assessment of hazardous environments.

[post_title] => XplorIR Solves CO Cross-Sensitivity for Hazmat Response [post_excerpt] => Learn how XplorIR accurately identifies toxic gases that can give air monitors false readings or inaccurate measurements. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => co-cross-sensitivity-and-xplorir [to_ping] => [pinged] => [post_modified] => 2024-11-01 15:35:10 [post_modified_gmt] => 2024-11-01 19:35:10 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24637 [menu_order] => 34 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [6] => WP_Post Object ( [ID] => 24635 [post_author] => 36 [post_date] => 2024-06-14 09:24:16 [post_date_gmt] => 2024-06-14 13:24:16 [post_content] =>

For reconnaissance teams at hazardous materials incidents, responders typically use a combination of 4-gas monitors, PID sensors, gamma detectors, temperature guns, and colorimetric papers. However, these tools have limitations due to cross-sensitivity issues, leading to potentially inaccurate readings and less reliable risk assessments. The XplorIR® offers a significant improvement by providing real-time identification of gases and vapors, reducing the problem of false readings and enabling more accurate risk assessments. By incorporating XplorIR, responders can more quickly and safely determine the presence of specific hazards, such as Hydrogen Fluoride or Carbon Dioxide, making it an essential addition to standard reconnaissance toolbox.

[post_title] => Building Your Recon Toolbox [post_excerpt] => Learn how the XplorIR is a logical addition to your set of recon tools. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => building-your-recon-toolbox [to_ping] => [pinged] => [post_modified] => 2024-11-01 15:37:27 [post_modified_gmt] => 2024-11-01 19:37:27 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24635 [menu_order] => 35 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [7] => WP_Post Object ( [ID] => 24639 [post_author] => 36 [post_date] => 2024-06-14 09:24:17 [post_date_gmt] => 2024-06-14 13:24:17 [post_content] =>

Photo Ionization Detectors (PIDs) are valuable tools for detecting a broad range of chemicals by measuring ionized gas samples with ultraviolet light. However, PIDs face limitations in accuracy due to their reliance on calibration standards and the need for gas-specific correction factors, which require knowing the identity of the gas. The XplorIR® addresses this challenge by providing real-time gas and vapor identification, enabling operators to apply the correct PID correction factors for more accurate readings and assess toxic risks based on specific contaminants. This advancement significantly enhances risk assessment and response efficiency, allowing for quicker and more accurate identification of hazards and sources, and making XplorIR a major improvement in emergency response technology since the introduction of the PID in the 1970s.

[post_title] => Expanding Your Toolbox: Pairing Your PID with FTIR [post_excerpt] => Learn about PID entry methods and how continuous air monitoring with XplorIR can identify unknown gases in the hotzone. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => detect-and-identify-with-pid-and-ftir [to_ping] => [pinged] => [post_modified] => 2024-11-01 15:42:34 [post_modified_gmt] => 2024-11-01 19:42:34 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24639 [menu_order] => 36 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [8] => WP_Post Object ( [ID] => 24643 [post_author] => 36 [post_date] => 2024-06-14 09:24:17 [post_date_gmt] => 2024-06-14 13:24:17 [post_content] =>

This app note discusses the challenges faced by emergency responders when dealing with mixed chemical products in the field. It highlights the limitations of existing chemical identification technologies and introduces our innovative approach with the XplorIR to identify up to 6 gas components within complex mixtures.

[post_title] => Breaking New Ground: Gas Mixture Analysis with XplorIR [post_excerpt] => Learn how the XplorIR identifies mixed chemical products and overcomes current chemical detection challenges through its ability to identify up to 6 gas components within complex mixtures. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => breaking-new-ground-gas-mixture-analysis-with-xplorir [to_ping] => [pinged] => [post_modified] => 2024-11-03 16:38:30 [post_modified_gmt] => 2024-11-03 21:38:30 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24643 [menu_order] => 37 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [9] => WP_Post Object ( [ID] => 24901 [post_author] => 36 [post_date] => 2024-06-10 09:36:50 [post_date_gmt] => 2024-06-10 13:36:50 [post_content] =>

AA analysis is not regularly performed in CAR T-cell experiments due to the complexity and sample volume limitations of traditional methods, but the REBEL device enables rapid analysis, low sample volume requirements and without the need for prior mass spectrometry expertise. Learn how to optimize your cell culture media for enhanced CAR T-cell therapy manufacturing.

This study explores the relationship between CAR T-cell activation, nutrient metabolism, and treatment efficacy. It highlights differences in amino acid (AA) concentrations in spent media between potent CAR T-cell phenotypes and less-active, exhausted ones. By using novel multi-cytokine backpacks (MCBs) in cell culture, the research aims to enhance T-cell manufacturing, focusing on the metabolic profiles linked to different phenotypes. The analysis revealed that certain AAs, such as alanine and glycine, accumulated during culture while others, like arginine, were consumed, indicating active metabolic pathways. With automated quantitation and low sample volume requirements, REBEL facilitated efficient AA quantification, underscoring its potential for optimizing CAR T-cell culture media. Overall, the findings suggest that understanding AA dynamics could improve CAR T-cell therapies.

[post_title] => Amino Acid Analysis Indicates Metabolic Differences in Multi-Cytokine Backpack-Manufactured CAR T-Cells [post_excerpt] => With automated quantitation and low sample volume requirements, the REBEL device enables rapid AA analysis compared to the many complexities in traditional analysis methods. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => amino-acid-analysis-indicates-metabolic-differences-in-multi-cytokine-backpack-manufactured-car-t-cells [to_ping] => [pinged] => [post_modified] => 2024-11-03 17:08:26 [post_modified_gmt] => 2024-11-03 22:08:26 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24901 [menu_order] => 93 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [10] => WP_Post Object ( [ID] => 26362 [post_author] => 15 [post_date] => 2024-11-15 15:04:30 [post_date_gmt] => 2024-11-15 20:04:30 [post_content] =>

ZipChip CE-MS was employed to assess mAb quality attributes directly from spent media, requiring only simple dilution without additional preparation. This technique facilitated daily monitoring of molecular weight, charge, and glycoform heterogeneity in mAbs produced in bioreactors with different glucose feeding strategies. Results showed improved product quality attributes from continuous glucose feeding compared to those produced with bolus glucose feeding, demonstrating ZipChip’s potential as a simple and effective tool for real-time monitoring of product quality in bioprocess development.

[post_title] => Enhanced Bioprocess Control: Assessing mAb Quality Through Direct Spent Media Analysis with ZipChip CE-MS [post_excerpt] => ZipChip CE-MS charge variant analysis enables streamlined monitoring of mAb quality attributes throughout cell culture, supporting bioprocess development. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => enhanced-bioprocess-control-assessing-mab-quality-through-direct-spent-media-analysis-with-zipchip-ce-ms [to_ping] => [pinged] => [post_modified] => 2024-11-15 15:04:31 [post_modified_gmt] => 2024-11-15 20:04:31 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26362 [menu_order] => 94 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [11] => WP_Post Object ( [ID] => 26372 [post_author] => 15 [post_date] => 2024-11-18 15:26:55 [post_date_gmt] => 2024-11-18 20:26:55 [post_content] =>

ZipChip CE-MS was used to analyze biosimilar mAb candidates, resolving charge variants and glycoforms with high sensitivity and short run times. This approach enabled rapid characterization of critical quality attributes, such as glycosylation and charge modifications, from early-stage cell line candidates. By providing detailed insights into post-translational modifications in a single assay, ZipChip facilitated efficient selection of mAbs closely matching the originator's quality profile, accelerating biosimilar development.

[post_title] => Sensitive Screening Of Biosimilar Candidate mAbs From Clonal Cell Lines Using ZipChip CE-MS [post_excerpt] => ZipChip CE-MS enables rapid and sensitive analysis of mAb glycosylation profiles and charge variants, streamlining biosimilar candidate selection from early-stage clone screening. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => sensitive-screening-of-biosimilar-candidate-mabs-from-clonal-cell-lines-using-zipchip-ce-ms [to_ping] => [pinged] => [post_modified] => 2024-11-18 15:26:56 [post_modified_gmt] => 2024-11-18 20:26:56 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26372 [menu_order] => 95 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [12] => WP_Post Object ( [ID] => 25372 [post_author] => 36 [post_date] => 2024-07-18 17:06:17 [post_date_gmt] => 2024-07-18 21:06:17 [post_content] =>

MAVERICK enables real-time monitoring of critical process parameters like glucose, lactate, and biomass in bioprocesses without the need for complex setups or prior modeling. Unlike traditional Raman spectroscopy methods that require extensive configuration and expert knowledge, MAVERICK offers a plug-and-play solution that can be implemented quickly and effectively across various cell lines and culture media. The system utilizes a de novo algorithm that works straight out of the box, measuring both static and dynamic parameters during bioprocess runs. Results from experiments with CHO and HEK293 cell cultures demonstrated that MAVERICK provides accurate readings that align closely with at-line measurements. The technology simplifies the monitoring process and helps ensure optimal cell culture conditions, enhancing overall product quality and yield. Overall, MAVERICK represents a significant advancement in in-line process analytical technology (PAT) for biomanufacturing.

[post_title] => Instant PAT Implementation with Raman-based MAVERICK [post_excerpt] => Learn about instant PAT implementation, where MAVERICK was used to monitor critical process parameters to create measurement chemometric models. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => instant-pat-implementation-with-raman-based-maverick [to_ping] => [pinged] => [post_modified] => 2024-11-08 12:19:58 [post_modified_gmt] => 2024-11-08 17:19:58 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25372 [menu_order] => 96 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [13] => WP_Post Object ( [ID] => 23402 [post_author] => 36 [post_date] => 2024-02-09 11:43:11 [post_date_gmt] => 2024-02-09 16:43:11 [post_content] =>

This document discusses the critical roles of glucose and lactate in bioprocessing, emphasizing the benefits of real-time monitoring using MAVEN. Traditional sampling methods limit process insight, but MAVEN allows for continuous measurement and control of these parameters, enhancing bioprocess characterization and management. The experiments demonstrated that a continuous glucose feeding strategy improves cell culture viability and product quality compared to daily bolus feeding. In particular, MAVEN prevented culture crashes and reduced high-mannose glycan levels in monoclonal antibodies, which can influence efficacy and stability. Overall, MAVEN facilitates more precise control and optimization of bioprocesses, leading to improved outcomes.

[post_title] => Continuous Monitoring and Control of Glucose and Lactate with MAVEN: Impact on Cell Culture Performance and Protein Quality [post_excerpt] => Traditional sampling methods limit process insight, but MAVEN allows for continuous measurement and control of these parameters, enhancing bioprocess optimization. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => maven-monitoring-glucose-lactate-cell-culture-quality [to_ping] => [pinged] => [post_modified] => 2024-11-08 12:22:45 [post_modified_gmt] => 2024-11-08 17:22:45 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23402 [menu_order] => 97 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [14] => WP_Post Object ( [ID] => 22939 [post_author] => 29 [post_date] => 2023-12-12 17:53:57 [post_date_gmt] => 2023-12-12 22:53:57 [post_content] => [post_title] => Real-time Monitoring of Key Bioprocess Parameters Using MAVERICK In-line Device in Culture Biosciences’ Cloud-connected Bioreactors [post_excerpt] => Bioprocessing 4.0 aims to leverage advanced digital technologies, automation, and data-driven approaches to transform biopharmaceutical production. The data generated utilizing Culture Bioscience’s bioreactors, cloud-based controllers and software console together with MAVERICK, a novel Raman spectroscopy powered in-line PAT device, was found to track closely with off-line measurements for multiple critical process parameters. The use of PAT in bioreactors provides in-line, continuous data about cell culture conditions, thereby enhancing process understanding and enabling precise bioprocess monitoring and control. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => maverick-application-notes-and-snapshots-real-time-monitoring-of-key-bioprocess [to_ping] => [pinged] => [post_modified] => 2024-08-01 10:50:53 [post_modified_gmt] => 2024-08-01 14:50:53 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=22939 [menu_order] => 98 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [15] => WP_Post Object ( [ID] => 8033 [post_author] => 29 [post_date] => 2023-05-01 11:52:32 [post_date_gmt] => 2023-05-01 15:52:32 [post_content] => [post_title] => Microchip CE/MS Peptide Mapping Workflow with Trypsin Digestion for the Analysis of Critical Quality Attributes of Monoclonal Antibodies [post_excerpt] => Peptide mapping is considered the gold standard for the analysis of biopharmaceuticals, including monoclonal antibodies. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-appnote-ls-zc-an-0020 [to_ping] => [pinged] => [post_modified] => 2024-08-01 13:35:51 [post_modified_gmt] => 2024-08-01 17:35:51 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=8033 [menu_order] => 99 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [16] => WP_Post Object ( [ID] => 7132 [post_author] => 15 [post_date] => 2022-11-30 17:54:23 [post_date_gmt] => 2022-11-30 22:54:23 [post_content] => [post_title] => Glucose Control [post_excerpt] => The online analyzer TRACE C2 Control allows a rapid and precise determination of glucose and lactate concentrations inside the bioreactor. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => application-report-glucose-control [to_ping] => [pinged] => [post_modified] => 2024-04-03 19:03:33 [post_modified_gmt] => 2024-04-03 23:03:33 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7132 [menu_order] => 158 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [17] => WP_Post Object ( [ID] => 7128 [post_author] => 15 [post_date] => 2022-11-30 17:43:33 [post_date_gmt] => 2022-11-30 22:43:33 [post_content] => [post_title] => Ethanol Dialysis [post_excerpt] => The online analyzer TRACE C2 Control allows a rapid and precise determination of the Ethanol concentration in the fermenter. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-application-report-ethanol [to_ping] => [pinged] => [post_modified] => 2024-04-03 19:04:22 [post_modified_gmt] => 2024-04-03 23:04:22 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7128 [menu_order] => 159 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [18] => WP_Post Object ( [ID] => 7107 [post_author] => 15 [post_date] => 2022-11-30 15:16:07 [post_date_gmt] => 2022-11-30 20:16:07 [post_content] => [post_title] => Methanol Dialysis [post_excerpt] => The online analyzer TRACE C2 Control allows a rapid and precise determination of the methanol concentration in the fermenter and provides the tools for a quick set-up of a feed control strategy [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-application-report-methanol [to_ping] => [pinged] => [post_modified] => 2024-04-03 19:05:13 [post_modified_gmt] => 2024-04-03 23:05:13 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7107 [menu_order] => 160 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [19] => WP_Post Object ( [ID] => 7104 [post_author] => 15 [post_date] => 2022-11-30 14:52:28 [post_date_gmt] => 2022-11-30 19:52:28 [post_content] => [post_title] => Glucose & Lactate (in Small Bioreactors) [post_excerpt] => The online analyzer TRACE C2 Control allows a rapid and precise determination of glucose and lactate concentrations inside small bioreactors. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-app-report-glucose-lactate-small-bioreactors [to_ping] => [pinged] => [post_modified] => 2024-04-03 19:11:45 [post_modified_gmt] => 2024-04-03 23:11:45 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7104 [menu_order] => 161 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [20] => WP_Post Object ( [ID] => 7101 [post_author] => 15 [post_date] => 2022-11-30 14:39:59 [post_date_gmt] => 2022-11-30 19:39:59 [post_content] => [post_title] => Glucose & Lactate [post_excerpt] => The online analyzer TRACE C2 Control allows a rapid and precise determination of glucose and lactate concentrations inside the bioreactor. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-app-report-glucose-lactate [to_ping] => [pinged] => [post_modified] => 2024-04-03 19:07:11 [post_modified_gmt] => 2024-04-03 23:07:11 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7101 [menu_order] => 162 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [21] => WP_Post Object ( [ID] => 24355 [post_author] => 15 [post_date] => 2024-05-02 09:30:58 [post_date_gmt] => 2024-05-02 13:30:58 [post_content] => [post_title] => Why are Fentanyl and Fake Pills so Deadly [post_excerpt] => Download this infographic to increase your knowledge about fentanyl awareness and review survey results conducted by Dynata. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => why-are-fentanyl-and-fake-pills-so-deadly-infographic [to_ping] => [pinged] => [post_modified] => 2024-09-11 10:46:45 [post_modified_gmt] => 2024-09-11 14:46:45 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24355 [menu_order] => 191 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [22] => WP_Post Object ( [ID] => 4835 [post_author] => 29 [post_date] => 2021-10-29 12:13:11 [post_date_gmt] => 2021-10-29 16:13:11 [post_content] => [post_title] => Rapid characterization of oligonucleotides using microfluidic CE-MS by ZipChip [post_excerpt] => This application note presents a CE-MS analysis of oligos by a ZipChip coupled to a QExactive HF mass spectrometer. This positive ESI mode method utilizes a MS-friendly background electrolyte (BGE), that eliminates the use of ion-paring agents such as hexafluoro isopropanol or alkyl amines. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-app-note-oligo-analysis [to_ping] => [pinged] => [post_modified] => 2024-08-01 13:24:15 [post_modified_gmt] => 2024-08-01 17:24:15 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=4835 [menu_order] => 292 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [23] => WP_Post Object ( [ID] => 4743 [post_author] => 20 [post_date] => 2021-10-08 08:40:23 [post_date_gmt] => 2021-10-08 12:40:23 [post_content] => [post_title] => Charge variant analysis with ZipChip and maXisII [post_excerpt] => A ZipChip capillary zone electrophoresis system coupled to Bruker maXis II UHR-QTOF offers an alternative selectivity to separate charge variants prior to MS analysis and affords a more complete intact mass characterization without adding complexity or high salt eluents. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-appnote-tn-53-charge-variant-analysis-with-zipchip-and-maxisii [to_ping] => [pinged] => [post_modified] => 2023-12-26 10:21:47 [post_modified_gmt] => 2023-12-26 15:21:47 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=4743 [menu_order] => 307 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [24] => WP_Post Object ( [ID] => 21763 [post_author] => 15 [post_date] => 2023-09-17 20:19:12 [post_date_gmt] => 2023-09-18 00:19:12 [post_content] => [post_title] => Glucose and Lactate Raman-Based Monitoring with MAVERICK: Performance in Spent Media [post_excerpt] => MAVERICK provides a plug-and-play, in-line, Raman based PAT solution for monitoring and control of glucose, lactate, and biomass in up to 6 bioreactors. This Application Snapshot shows the results from experiments to demonstrate the selectivity of glucose and lactate measurements from MAVERICK in complex spent media samples from CHO and HEK293 cultures. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => maverick-application-notes-and-snapshots-ls-mv-an-0001 [to_ping] => [pinged] => [post_modified] => 2024-08-01 13:44:37 [post_modified_gmt] => 2024-08-01 17:44:37 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=21763 [menu_order] => 312 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [25] => WP_Post Object ( [ID] => 2287 [post_author] => 32 [post_date] => 2021-09-10 13:33:28 [post_date_gmt] => 2021-09-10 17:33:28 [post_content] => [post_title] => A ZipChip Based CZE-MS Analysis for Quick Assessment of Biotherapeutics [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => a-zipchip-based-cze-ms-analysis-for-quick-assessment-of-biotherapeutics [to_ping] => [pinged] => [post_modified] => 2024-03-26 14:33:10 [post_modified_gmt] => 2024-03-26 18:33:10 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=2287 [menu_order] => 317 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [26] => WP_Post Object ( [ID] => 1209 [post_author] => 29 [post_date] => 2021-06-21 14:28:37 [post_date_gmt] => 2021-06-21 18:28:37 [post_content] => [post_title] => From comprehensive characterization to monitoring product degradation characteristics [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-native-charge-variant-analysis-of-biotherapeutics-using-zipchip-ce-esi-ms [to_ping] => [pinged] => [post_modified] => 2024-08-01 13:37:38 [post_modified_gmt] => 2024-08-01 17:37:38 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/zipchip-native-charge-variant-analysis-of-biotherapeutics-using-zipchip-ce-esi-ms/ [menu_order] => 328 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [27] => WP_Post Object ( [ID] => 1163 [post_author] => 20 [post_date] => 2020-12-11 19:14:54 [post_date_gmt] => 2020-12-12 00:14:54 [post_content] => [post_title] => Charge Variant Analysis Coupled to a SCIEX TripleTOF® 6600+ System Mass Spectrometer [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-charge-variant-analysis-coupled-to-a-sciex-tripletof-6600-system-mass-spectrometer [to_ping] => [pinged] => [post_modified] => 2023-12-26 10:22:46 [post_modified_gmt] => 2023-12-26 15:22:46 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/zipchip-charge-variant-analysis-coupled-to-a-sciex-tripletof-6600-system-mass-spectrometer/ [menu_order] => 333 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [28] => WP_Post Object ( [ID] => 1161 [post_author] => 38 [post_date] => 2020-11-16 23:18:26 [post_date_gmt] => 2020-11-17 04:18:26 [post_content] => [post_title] => High-Throughput Intact Mass Analysis of mAb Based Therapeutics [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-application-note-high-throughput-intact-mass-analysis-of-mab-based-therapeutics [to_ping] => [pinged] => [post_modified] => 2024-10-01 11:07:06 [post_modified_gmt] => 2024-10-01 15:07:06 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/zipchip_application-note_high-throughput-intact-mass-analysis-of-mab-based-therapeutics/ [menu_order] => 334 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [29] => WP_Post Object ( [ID] => 7615 [post_author] => 20 [post_date] => 2023-01-25 18:19:44 [post_date_gmt] => 2023-01-25 23:19:44 [post_content] => [post_title] => RPMI 1640 Medium Analysis with the REBEL: Accuracy and Reproducibility Across Multiple Devices [post_excerpt] => This extensive fresh media analysis experiment provides an example of the accuracy and reproducibility of the REBEL device obtained with RPMI media. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-app-snap-rpmi-1640-medium-analysis [to_ping] => [pinged] => [post_modified] => 2023-12-26 09:41:22 [post_modified_gmt] => 2023-12-26 14:41:22 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7615 [menu_order] => 341 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [30] => WP_Post Object ( [ID] => 7612 [post_author] => 20 [post_date] => 2023-01-25 18:10:04 [post_date_gmt] => 2023-01-25 23:10:04 [post_content] => [post_title] => Screening for Component Diversity in CHO Cell Culture Media [post_excerpt] => At-line amino acid analysis can speeds up cell culture media and feeding strategy optimization for bioprocess development. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-app-snap-screening-for-component-diversity [to_ping] => [pinged] => [post_modified] => 2023-12-26 09:41:47 [post_modified_gmt] => 2023-12-26 14:41:47 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7612 [menu_order] => 342 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [31] => WP_Post Object ( [ID] => 1144 [post_author] => 20 [post_date] => 2020-10-21 21:41:48 [post_date_gmt] => 2020-10-22 01:41:48 [post_content] => [post_title] => High variations of analyte levels in Terrific broth (TB) media [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel_applications_high-variations-of-analyte-levels-are-detected-in-terrific-broth-tb-media [to_ping] => [pinged] => [post_modified] => 2023-12-26 09:38:07 [post_modified_gmt] => 2023-12-26 14:38:07 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/rebel_applications_high-variations-of-analyte-levels-are-detected-in-terrific-broth-tb-media/ [menu_order] => 344 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [32] => WP_Post Object ( [ID] => 1188 [post_author] => 38 [post_date] => 2021-04-20 13:36:10 [post_date_gmt] => 2021-04-20 17:36:10 [post_content] => [post_title] => Application Snapshot Booklet Cell and Gene Therapy [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-applications-snapshot-booklet-cell-and-gene-therapy [to_ping] => [pinged] => [post_modified] => 2024-10-01 11:01:14 [post_modified_gmt] => 2024-10-01 15:01:14 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/rebel_applications_snapshot-booklet-cell-and-gene-therapy/ [menu_order] => 351 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [33] => WP_Post Object ( [ID] => 1142 [post_author] => 20 [post_date] => 2020-10-21 21:32:15 [post_date_gmt] => 2020-10-22 01:32:15 [post_content] => [post_title] => How comparable are different vendors' LB media? [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel_applications_how-comparable-are-different-vendors-lb-media [to_ping] => [pinged] => [post_modified] => 2023-12-26 09:37:51 [post_modified_gmt] => 2023-12-26 14:37:51 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/rebel_applications_how-comparable-are-different-vendors-lb-media/ [menu_order] => 359 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [34] => WP_Post Object ( [ID] => 1146 [post_author] => 38 [post_date] => 2020-10-21 22:42:46 [post_date_gmt] => 2020-10-22 02:42:46 [post_content] => [post_title] => Investigating the high nutrient variations in Super Optimal Broth [post_excerpt] => Cultures’ growth rates and productivities may differ when different vendor’s media are used in otherwise identical experiments. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-applications-investigating-the-high-nutrient-variations-in-super-optimal-broth [to_ping] => [pinged] => [post_modified] => 2024-10-01 10:57:17 [post_modified_gmt] => 2024-10-01 14:57:17 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/rebel_applications_investigating-the-high-nutrient-variations-in-super-optimal-broth/ [menu_order] => 361 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [35] => WP_Post Object ( [ID] => 1148 [post_author] => 20 [post_date] => 2020-10-21 22:48:51 [post_date_gmt] => 2020-10-22 02:48:51 [post_content] => [post_title] => Probing formulation differences in Super Optimal Broth [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel_applications_probing-formulation-differences-in-super-optimal-broth-with-catabolite-repression-media [to_ping] => [pinged] => [post_modified] => 2023-12-26 09:39:08 [post_modified_gmt] => 2023-12-26 14:39:08 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/rebel_applications_probing-formulation-differences-in-super-optimal-broth-with-catabolite-repression-media/ [menu_order] => 363 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [36] => WP_Post Object ( [ID] => 796 [post_author] => 20 [post_date] => 2017-12-06 14:29:19 [post_date_gmt] => 2017-12-06 19:29:19 [post_content] => [post_title] => Analysis of Reduced mAbs and ADCs [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => analysis-reduced-mabs-antibody-drug-conjugates-using-zipchip-platform [to_ping] => [pinged] => [post_modified] => 2023-12-26 10:22:29 [post_modified_gmt] => 2023-12-26 15:22:29 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/analysis-reduced-mabs-antibody-drug-conjugates-using-zipchip-platform/ [menu_order] => 364 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [37] => WP_Post Object ( [ID] => 1150 [post_author] => 20 [post_date] => 2020-10-21 22:54:36 [post_date_gmt] => 2020-10-22 02:54:36 [post_content] => [post_title] => Similarities between different vendors’ 2X YT liquid media [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel_applications_investigating-the-similarities-between-different-vendors-2x-yt-liquid-media [to_ping] => [pinged] => [post_modified] => 2023-12-26 09:39:27 [post_modified_gmt] => 2023-12-26 14:39:27 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/rebel_applications_investigating-the-similarities-between-different-vendors-2x-yt-liquid-media/ [menu_order] => 365 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [38] => WP_Post Object ( [ID] => 1177 [post_author] => 20 [post_date] => 2021-03-26 14:10:44 [post_date_gmt] => 2021-03-26 18:10:44 [post_content] => [post_title] => ZipChip for profiling and characterization of antibody charge heterogeneity [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip_app-note_zipchip-for-profiling-and-characterization-of-antibody-charge-heterogeneity [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:01:15 [post_modified_gmt] => 2023-12-26 17:01:15 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/zipchip_app-note_zipchip-for-profiling-and-characterization-of-antibody-charge-heterogeneity/ [menu_order] => 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The XplorIR Quantification Package provides hazmat responders with the capability to not only identify thousands of gases and vapors, but also quantify them in real-time on scene. This represents the only device of it's kind which can accurately detect, identify, and quantify, thousands of gases in seconds. With this unmatched capability, responders are able to respond swiftly to assess atmospheric conditions and make rapid decisions on PPE selection, exposure potential, mitigation techniques, and influence tactical considerations.

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In this flyer, learn how you can optimize the performance of your REBEL device with a preventive maintenance plan. There are various parts for the REBEL device and with routine maintenance, you can keep your device running efficiently with optimal analysis. We offer a few options for service plans to support your needs.

*For multi-year Premium plan, one free of charge Certified Training is on annual “use it or lose it” basis.
[post_title] => Optimize Your REBEL’s Performance with a Preventive Maintenance Plan [post_excerpt] => Learn how you can optimize the performance of REBEL with a preventive maintenance plan and see what is included. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => optimize-your-rebels-performance-with-a-preventive-maintenance-plan [to_ping] => [pinged] => [post_modified] => 2024-11-13 13:52:07 [post_modified_gmt] => 2024-11-13 18:52:07 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26146 [menu_order] => 27 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 25230 [post_author] => 36 [post_date] => 2024-07-09 13:02:58 [post_date_gmt] => 2024-07-09 17:02:58 [post_content] =>

Combining Terumo BCT's Quantum Flex platform with 908 Devices’ MAVEN will help cell therapy manufacturers reduce time-consuming manual steps that increase manufacturing costs and risks. It will also help advance the development of life-saving cell and gene therapies by providing insights into and control of one of the largest components of cell therapy development and manufacturing.

Automated monitoring of glucose and lactate on the Quantum Flex Cell Expansion System

Knowing what is happening inside your bioreactor is critical for cell expansion

Glucose and lactate concentrations can serve as leading indicators of the health and growth kinetics of your cells. When considered alongside perfusion rate, these metabolic indicators can help optimize media usage and harvest time. Quantum Flex paired with MAVEN from 908 Devices brings you continuous monitoring of glucose and lactate levels inside your bioreactor.

MAVEN integrates easily with Quantum Flex. The device clamps securely to the Quantum Flex bag pole, and a single-use diffusion flow cell is sterile-welded into the waste line of the Quantum Flex Cell Expansion Set.

Only the small glucose and lactate molecules from the bioreactor medium diffuse through a semi-permeable membrane inside the flow cell, moving into a transport buffer solution. The solution travels through the tubing to a biosensor inside MAVEN.

MAVEN analyzes the glucose and lactate concentrations. Results are available in near-real time and can be read on your computer using installed software.

Sensor type:
Replaceable enzyme-based electrochemical biosensor

Glucose measurement range:
From 0.01 to 40 g/L concentration

Lactate measurement range:
From 0.05 to 10 g/L concentration

Sensor operating life:
5,000 measurements or 30 days

[post_title] => Automated Monitoring on the Quantum Flex [post_excerpt] => Learn how Terumo Blood and Cell Technologies' Quantum Flex cell expansion system and 908 Devices' MAVEN can work together to help your cells thrive and optimize your cell expansion process. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => automated-monitoring-on-the-quantum-flex [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:46:54 [post_modified_gmt] => 2024-08-30 15:46:54 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25230 [menu_order] => 28 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 25083 [post_author] => 36 [post_date] => 2024-06-18 07:03:19 [post_date_gmt] => 2024-06-18 11:03:19 [post_content] =>

This flyer describes the XplorIR's new identification with simultaneous quantification capability. The XplorIR can identify over 5,600 gases/vapors with extreme selectivity within seconds. With the new quantification package, the XplorIR can now quantify nearly 5,000 gases/vapors at parts-per-million (ppm) levels. This is done without any calibration required.

It’s one thing to know if a hazardous gas or vapor is present at an incident, and another to know what the product is. But what if you could also know how much of the hazard exists in the atmosphere? That requires quantification, and the XplorIR® now provides this critical piece of information.

The XplorIR, based on Fourier transform infrared (FTIR) spectroscopy, can identify over 5,600 gases/vapors with extreme selectivity within seconds. With the new quantification package, the XplorIR can now quantify nearly 5,000 gases/vapors at parts-per-million (ppm) levels. This is done without any calibration required.

FTIR measurements are inherently quantitative, and the spectral response is linear with respect to product concentration. Using a reference library based on known chemical concentrations, the XplorIR can determine the ppm of a product captured within its 2-meter gas cell and report that concentration along with the product identity.

Once the concentration is known, it can easily be compared to the Immediately Dangerous to Life and Health (ILDH) level of the product within the XplorIR software. This allows you to make rapid tactical decisions about remediation and decon with just a few button clicks.

Going further, the XplorIR uses a proprietary, automated process which combines molecular functional groups with measured spectra to estimate quantitative data for nearly all library entries. This extends the quantitative capabilities from a few hundred compounds to several thousand. With its ability to identify and quantify up to 6 mixture components at one time, the XplorIR is a game-changer for chemical response scenarios such as clandestine labs and other situations involving complex gas and vapor environments.

Key Attributes

  • The only handheld device for rapid trace detection and identification of pesticides at nanogram levels, in the field
  • Trace capability allows for exterior packaging sampling, reducing exposure risk
  • Provides actionable data at the point of need with results in less than a minute
  • Identify numerous pesticides by name to guide clean up efforts and keep personnel on site safe
  • Developed in partnership with the United States Forest Service (USFS)
[post_title] => XplorIR Quantification Package [post_excerpt] => The XplorIR can now simultaneously identify and quantify hazardous gases and vapors with this new package pairing. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => xplorir-quantification-package [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:47:35 [post_modified_gmt] => 2024-08-30 15:47:35 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25083 [menu_order] => 29 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 24657 [post_author] => 36 [post_date] => 2024-06-14 09:24:16 [post_date_gmt] => 2024-06-14 13:24:16 [post_content] =>

Traditional first-entry meters only detect the presence of gases downrange, without accurately identifying their specific chemical compounds. During an explosion at a clandestine meth lab, learn how the XplorIR provides positive gas identification of over 5600 chemicals, even in complex gas mixtures.

Once the resulting flames have been extinguished, your recon team performs an initial site assessment. While LEL readings are relatively low, CO and PID readings are extremely high. Neighbors complain of acrid odors and difficulty breathing. It seems you have just stepped into a clandestine meth lab, and you need answers… FAST!

Such incidents are far too common for first responders and mitigating them requires actionable intelligence on the myriad toxic gases and vapors filling the atmosphere. While multi-gas meters and PIDs play a critical role in these scenarios, such first entry devices don’t provide the gas and vapor identification capability required to tell the whole story. That’s where the XplorIR® comes in.

The hand-held XplorIR gas and vapor system can identify over 5,600 chemical products in seconds downrange

And with its sophisticated atmospheric compensation and mixture analysis algorithms, the XplorIR can report up to 6 compounds within the dirtiest of environments with minimal operator interaction. And when expert help is needed in the middle of the night, reach back scientists are on call to review the XplorIR data you upload to the cloud using the TeamLeader app on your smartphone.

Whether a complex toxic gas release is nefarious or unintentional, the next time your agency is called to secure public and environmental safety, be prepared with the XplorIR. It will definitely save time, and it just might save lives.

[post_title] => XplorIR: Gas Identification for Rapid Response [post_excerpt] => Learn how the XplorIR provides positive gas identification during an explosion at a clandestine meth lab. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => threat-brief-xplorir-mixture-analysis [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:48:10 [post_modified_gmt] => 2024-08-30 15:48:10 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24657 [menu_order] => 30 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 24287 [post_author] => 36 [post_date] => 2024-04-24 13:27:24 [post_date_gmt] => 2024-04-24 17:27:24 [post_content] =>

Sample comparison, and time-course data visualization from multiple samples, for all analytes, in an instant.

Visualize time course data for glucose, lactate, and biomass and compare runs. Values are provided in 1-minute intervals.

Visualize time course data for glucose and lactate, and display the glucose feed-pump speed for run duration to compare runs.

[post_title] => Faster Bioprocess Data Visualization [post_excerpt] => Expedite your 908 Devices bioprocess data visualization with the JMP add-in tool that delivers data visualization in less than a minute for run and sample comparisons. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => faster-bioprocess-data-visualization [to_ping] => [pinged] => [post_modified] => 2024-08-14 16:26:04 [post_modified_gmt] => 2024-08-14 20:26:04 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24287 [menu_order] => 91 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [5] => WP_Post Object ( [ID] => 7557 [post_author] => 36 [post_date] => 2023-01-16 17:15:33 [post_date_gmt] => 2023-01-16 22:15:33 [post_content] =>

Unlike in manual or automated sampling, measurements are performed without any loss of bioreactor volume and without increased risk of process contamination.

BE A REBEL AND REAP THE REWARDS.

Combine REBEL’s at-line analysis of amino acids and vitamins with MAVEN’s on-line monitoring and control of glucose and lactate to get unambiguous answers where and when you need them.

  • Compatible with Most Bioreactors and Fermenters
  • Automation Included
  • Advanced Connectivity
[post_title] => MAVEN Brochure [post_excerpt] => MAVEN offers monitoring and control of glucose and lactate concentrations during cell culture and fermentation. Download this brochure to learn more. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => maven-brochure [to_ping] => [pinged] => [post_modified] => 2024-08-20 11:23:12 [post_modified_gmt] => 2024-08-20 15:23:12 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7557 [menu_order] => 92 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [6] => WP_Post Object ( [ID] => 25616 [post_author] => 29 [post_date] => 2024-08-19 09:20:53 [post_date_gmt] => 2024-08-19 13:20:53 [post_content] =>
[post_title] => Trace Identification of Nitazenes [post_excerpt] => This mission brief covers the advantages of using MX908 for the trace identification of nitazenes. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-identification-of-nitazenes [to_ping] => [pinged] => [post_modified] => 2024-08-21 21:45:49 [post_modified_gmt] => 2024-08-22 01:45:49 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25616 [menu_order] => 164 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [7] => WP_Post Object ( [ID] => 6910 [post_author] => 36 [post_date] => 2022-11-08 10:05:26 [post_date_gmt] => 2022-11-08 15:05:26 [post_content] =>

The increasing size of the illegal marijuana market has given rise to an increasing number of trespass cannabis cultivation throughout the world. The heavy use of toxic pesticides by these illegal growers has had significant impact on the environment and wildlife. Many of these pesticides are so toxic, they are heavily restricted or even completely banned by many governments. In addition to the threat these pesticides pose to the environment, they also pose a great threat to responding law enforcement and agencies tasked with dismantling these operations.

With the addition of the pesticide capabilities, the MX908 provides critical identification of toxic pesticides in the field, allowing users to act immediately, while keeping themselves safe. Whether it be on site at an illegal marijuana grow, or at the border identifying smuggled pesticides, the MX908 provides accurate identification of pesticides at trace levels, in a handheld device, for the first time ever.

  • The only handheld device for rapid trace detection and identification of pesticides at nanogram levels, in the field
  • Trace capability allows for exterior packaging sampling, reducing exposure risk
  • Provides actionable data at the point of need with results in less than a minute
  • Identify numerous pesticides by name to guide clean up efforts and keep personnel on site safe
  • Developed in partnership with the United States Forest Service (USFS)

A single drop of Carbofuran is enough to kill an adult human. Here a ~1 liter bottle is found at a trespass grow site.

Identifying containers and crop sprayers that have pesticides present reduce the cost of clean up and keep responders safe.

[post_title] => Identify Pesticides at Illegal Marijuana Grows [post_excerpt] => With the addition of the pesticide capabilities, the MX908 provides critical identification of toxic pesticides in the field, allowing users to act immediately, while keeping themselves safe. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => mx908-mission-brief-pesticides [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:54:54 [post_modified_gmt] => 2024-08-30 15:54:54 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6910 [menu_order] => 165 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [8] => WP_Post Object ( [ID] => 21577 [post_author] => 36 [post_date] => 2023-09-08 13:47:13 [post_date_gmt] => 2023-09-08 17:47:13 [post_content] =>

REBEL Certified User Training

[post_title] => REBEL Certified User Training [post_excerpt] => Get the best user experience with the REBEL at-line spent media analyzer. Our training course is for new and experienced users who want to refresh their REBEL device operation skills. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-brochures-and-flyers-ls-rb-fl-0002 [to_ping] => [pinged] => [post_modified] => 2024-08-27 14:11:18 [post_modified_gmt] => 2024-08-27 18:11:18 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=21577 [menu_order] => 176 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [9] => WP_Post Object ( [ID] => 6548 [post_author] => 36 [post_date] => 2022-09-28 13:24:01 [post_date_gmt] => 2022-09-28 17:24:01 [post_content] =>

The REBEL Spent Media Analysis (SMA) kit is designed to give you all the consumable components needed to run your samples quickly and move your projects forward faster.

Choose the purchasing style that suits your lab:

  • One-time: Order one or more kits at full price for shipment.
  • Subscription: Order 6 or 12 kits at a time, shipped to you on a schedule you choose.
  • Thoughtful shipping: No matter how you buy, every kit ships overnight with proper packing to keep critical components chilled between 2-8° C at all times. Buy with a subscription to keep a steady stream of shipments flowing to your lab, without filling up valuable refrigerator space.
  • Comprehensive package: Each kit includes BGE, diluent, a REBEL chip, standards, and microwell plates.
  • Packed for 200 runs: Make your buying decision based on kit consumption and your upcoming projects.
[post_title] => REBEL Spent Media Analysis Kits [post_excerpt] => The REBEL Spent Media Analysis (SMA) kit is designed to give you all the consumable components needed to run your samples quickly and move your projects forward faster. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-flyer-spent-media-analysis-kits [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:56:15 [post_modified_gmt] => 2024-08-30 15:56:15 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6548 [menu_order] => 177 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [10] => WP_Post Object ( [ID] => 6248 [post_author] => 29 [post_date] => 2022-07-12 09:19:54 [post_date_gmt] => 2022-07-12 13:19:54 [post_content] =>

MX908 Remote App

Export Results, Add Custom Notes, and Access Support

Get the MX908 Remote App on Google Play or the App Store

Pair the MX908 with a phone or tablet

Send reports, add custom notes and access support with the touch of a button

[post_title] => MX908 Remote App [post_excerpt] => Download this flyer to learn more about the remote app now available for MX908. The MX908 remote app is available for download on Google Play or Apple App Store. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => mx908-remote-app [to_ping] => [pinged] => [post_modified] => 2024-08-21 21:47:31 [post_modified_gmt] => 2024-08-22 01:47:31 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6248 [menu_order] => 192 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [11] => WP_Post Object ( [ID] => 5735 [post_author] => 36 [post_date] => 2022-03-25 11:24:22 [post_date_gmt] => 2022-03-25 15:24:22 [post_content] =>
[post_title] => CBRN History Overview [post_excerpt] => Chemical warfare agents have evolved greatly over the last 100 years, download this timeline flyer to learn more. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => cbrn-history-overview [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:57:12 [post_modified_gmt] => 2024-08-30 15:57:12 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=5735 [menu_order] => 236 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [12] => WP_Post Object ( [ID] => 5701 [post_author] => 36 [post_date] => 2022-03-11 10:54:57 [post_date_gmt] => 2022-03-11 15:54:57 [post_content] =>
[post_title] => Operational Impact of Fourth Generation Agents and Pharmaceutical Based Agents [post_excerpt] => The MX908 handheld mass spectrometer is the only device able to detect and identify both A-Series Agents and PBAs at trace levels in solid, liquid, vapor, and aerosol forms. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => operational-impact-of-fourth-generation-agents-and-pharmaceutical-based-agents [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:57:55 [post_modified_gmt] => 2024-08-30 15:57:55 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=5701 [menu_order] => 242 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [13] => WP_Post Object ( [ID] => 5317 [post_author] => 36 [post_date] => 2022-02-02 14:56:00 [post_date_gmt] => 2022-02-02 19:56:00 [post_content] =>
[post_title] => MX908 Brochure [post_excerpt] => Download this brochure to learn how this rugged, handheld device enables real-time trace-level detection. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => mx908-brochure [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:58:52 [post_modified_gmt] => 2024-08-30 15:58:52 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=5317 [menu_order] => 262 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [14] => WP_Post Object ( [ID] => 24843 [post_author] => 36 [post_date] => 2024-06-04 10:12:50 [post_date_gmt] => 2024-06-04 14:12:50 [post_content] =>

Our ZipChip CVA kit takes the guesswork out of method development. Characterizing your samples with ZipChip capillary electrophoresis coupled to your high-resolution MS, you're able to assess charge heterogeneity, identify basic and acidic variants, acquire accurate mass information, and profile glycoforms, all in a single analysis.

ZipChip CVA Consumables

[post_title] => Full Charge Variant Analysis with Peak Identification Using ZipChip CE-MS [post_excerpt] => ZipChip CVA kit. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => full-charge-variant-analysis-with-peak-identification-using-zipchip-ce-ms [to_ping] => [pinged] => [post_modified] => 2024-08-30 11:59:29 [post_modified_gmt] => 2024-08-30 15:59:29 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24843 [menu_order] => 278 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [15] => WP_Post Object ( [ID] => 5077 [post_author] => 36 [post_date] => 2021-12-17 09:39:33 [post_date_gmt] => 2021-12-17 14:39:33 [post_content] =>

1. Application

2. Chip

3. Kit

[post_title] => ZipChip Consumables Guide [post_excerpt] => Learn how to take the guesswork out of method development with ZipChip. Breeze through your selection in three quick steps. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-consumables-guide [to_ping] => [pinged] => [post_modified] => 2024-08-30 12:00:02 [post_modified_gmt] => 2024-08-30 16:00:02 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=5077 [menu_order] => 279 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [16] => WP_Post Object ( [ID] => 4837 [post_author] => 36 [post_date] => 2021-10-29 12:17:00 [post_date_gmt] => 2021-10-29 16:17:00 [post_content] =>
  • High-resolution accurate mass identification and quantitation
    with CE-MS
  • No ion-pairing agents; no instrument contamination
  • Orthogonal to LC-based separation
  • Analysis in minutes with simple sample prep
[post_title] => Hassle-Free Oligo Characterization with ZipChip [post_excerpt] => The newly released ZipChip® oligos kit provides a simple, sensitive, dilute-and-shoot method for rapid analysis of oligonucleotides, applicable to various sizes and modifications. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-flyer-oligo-kit [to_ping] => [pinged] => [post_modified] => 2024-08-21 14:17:49 [post_modified_gmt] => 2024-08-21 18:17:49 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=4837 [menu_order] => 291 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [17] => WP_Post Object ( [ID] => 21733 [post_author] => 36 [post_date] => 2023-09-17 20:19:08 [post_date_gmt] => 2023-09-18 00:19:08 [post_content] =>
  • Control feeding pumps directly or send the measured parameters to an existing automation system
  • Securely monitor your bioprocess from anywhere with optional remote monitoring via a web browser
[post_title] => MAVERICK Brochure [post_excerpt] => Real-time bioprocess monitoring and control, right out of the box. In-line measurements of multiple critical parameters across media, across processes, across mammalian cell lines, across scales. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => maverick-brochures-and-flyers-ls-mv-br-0001 [to_ping] => [pinged] => [post_modified] => 2024-08-30 12:01:10 [post_modified_gmt] => 2024-08-30 16:01:10 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=21733 [menu_order] => 311 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [18] => WP_Post Object ( [ID] => 827 [post_author] => 36 [post_date] => 2018-06-04 04:28:30 [post_date_gmt] => 2018-06-04 08:28:30 [post_content] =>

ZipChip leverages microfluidic-based Capillary Electrophoresis (CE) and electrospray ionization technology to simplify sample preparation, perform high-resolution separations with reduced analysis times, and directly introduce samples into a Thermo Fisher Scientific, Bruker, or Sciex mass spectrometer. Achieve faster results with the ZipChip CE-MS device.

Protein Characterization:
Oligonucleotides:
Small Molecules
Metabolomics:
[post_title] => ZipChip: Accelerate Your MS Characterization [post_excerpt] => Rapid protein characterization and metabolomic analysis with microfluidic technology for highly efficient separations of complex samples. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-platform-brochure [to_ping] => [pinged] => [post_modified] => 2024-08-28 16:38:39 [post_modified_gmt] => 2024-08-28 20:38:39 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/zipchip-platform-brochure/ [menu_order] => 329 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [19] => WP_Post Object ( [ID] => 953 [post_author] => 38 [post_date] => 2019-09-23 18:54:39 [post_date_gmt] => 2019-09-23 22:54:39 [post_content] =>
[post_title] => Novichoks Mission Brief [post_excerpt] => Review this one sheet on Fourth Generation Agents that the MX908 can detect and identify at trace levels. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => mission-brief-novichok [to_ping] => [pinged] => [post_modified] => 2024-10-02 07:29:56 [post_modified_gmt] => 2024-10-02 11:29:56 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/mission-brief-novichok/ [menu_order] => 453 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [20] => WP_Post Object ( [ID] => 929 [post_author] => 36 [post_date] => 2019-08-08 17:31:48 [post_date_gmt] => 2019-08-08 21:31:48 [post_content] =>

CELL CULTURE MEDIA ANALYSIS MATTERS

REBEL?

[post_title] => REBEL Brochure [post_excerpt] => The REBEL is a novel, dedicated cell culture media analyzer designed for rapid, easy, and efficient amino acid and nutrient analysis. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-brochure [to_ping] => [pinged] => [post_modified] => 2024-08-29 16:49:47 [post_modified_gmt] => 2024-08-29 20:49:47 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/rebel-brochure/ [menu_order] => 472 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [21] => WP_Post Object ( [ID] => 1190 [post_author] => 36 [post_date] => 2021-05-07 13:48:09 [post_date_gmt] => 2021-05-07 17:48:09 [post_content] =>
[post_title] => Expanded Capability for Toxic Aerosol Detection and Identification [post_excerpt] => Review the mission brief to learn how MX908 with Aero allows users to detect and identify aerosolized threats at trace levels. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => aerosol-detection-identification [to_ping] => [pinged] => [post_modified] => 2024-08-30 12:03:48 [post_modified_gmt] => 2024-08-30 16:03:48 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/mx908_mission-brief-aerosol/ [menu_order] => 525 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [22] => WP_Post Object ( [ID] => 968 [post_author] => 36 [post_date] => 2019-10-28 14:14:40 [post_date_gmt] => 2019-10-28 18:14:40 [post_content] =>
[post_title] => Fentanyl Mission Brief [post_excerpt] => Review this one sheet on MX908 detection and identification of fentanyl and its thousands of analogs. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => fentanyl-mission-brief [to_ping] => [pinged] => [post_modified] => 2024-08-21 16:35:42 [post_modified_gmt] => 2024-08-21 20:35:42 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/mission-brief-fentanyl-2/ [menu_order] => 526 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 23 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 26146 [post_author] => 36 [post_date] => 2024-10-11 12:57:11 [post_date_gmt] => 2024-10-11 16:57:11 [post_content] =>

In this flyer, learn how you can optimize the performance of your REBEL device with a preventive maintenance plan. There are various parts for the REBEL device and with routine maintenance, you can keep your device running efficiently with optimal analysis. We offer a few options for service plans to support your needs.

*For multi-year Premium plan, one free of charge Certified Training is on annual “use it or lose it” basis.
[post_title] => Optimize Your REBEL’s Performance with a Preventive Maintenance Plan [post_excerpt] => Learn how you can optimize the performance of REBEL with a preventive maintenance plan and see what is included. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => optimize-your-rebels-performance-with-a-preventive-maintenance-plan [to_ping] => [pinged] => [post_modified] => 2024-11-13 13:52:07 [post_modified_gmt] => 2024-11-13 18:52:07 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26146 [menu_order] => 27 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 23 [max_num_pages] => 0 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => 1 [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => 1 [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => 1 [query_vars_hash:WP_Query:private] => bd84152daeaa85286be6b567c65d321f [query_vars_changed:WP_Query:private] => 1 [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )
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[post_title] => ThreatID: Lithium-ion Battery Decommissioning [post_excerpt] => Learn how ThreatID identified hazardous gas components generated during a Lithium-Ion battery decommissioning. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => lithium-ion-battery-decommissioning [to_ping] => [pinged] => [post_modified] => 2024-12-03 15:19:21 [post_modified_gmt] => 2024-12-03 20:19:21 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24648 [menu_order] => 18 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 24664 [post_author] => 36 [post_date] => 2024-06-14 09:24:15 [post_date_gmt] => 2024-06-14 13:24:15 [post_content] =>

Hundreds of ThreatIDs have been deployed by the U.S. Postal Inspection Service for their Dangerous Mail Program. Learn why USPIS chose the ThreatID for advanced screening and detection; distinguishing it from other FTIR technologies.

[post_title] => ThreatID Case Study: United States Postal Inspection Service [post_excerpt] => Learn why USPIS chose the ThreatID for advanced screening and detection, distinguishing it from other FTIR technologies. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => uspis [to_ping] => [pinged] => [post_modified] => 2024-12-03 15:49:41 [post_modified_gmt] => 2024-12-03 20:49:41 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24664 [menu_order] => 20 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 24430 [post_author] => 36 [post_date] => 2024-05-09 16:09:44 [post_date_gmt] => 2024-05-09 20:09:44 [post_content] =>
[post_title] => Trace Drug Identification at the Border: 3 Scenarios from the New Zealand Customs Service [post_excerpt] => Whether using trace identification features for drug traffickers, deploying vapor capabilities to analyze threats or implementing the explosive functionality to assess risk to the public, the New Zealand Customs Service has seen tremendous benefit from 908 Devices' MX908. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-drug-identification-at-the-border-3-scenarios-from-the-new-zealand-customs-service [to_ping] => [pinged] => [post_modified] => 2024-12-04 16:18:57 [post_modified_gmt] => 2024-12-04 21:18:57 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24430 [menu_order] => 40 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 23145 [post_author] => 36 [post_date] => 2024-01-25 09:17:49 [post_date_gmt] => 2024-01-25 14:17:49 [post_content] =>

On average, the U.S. Postal Service processes and delivers 421.4 million pieces of mail each day. In fiscal year 2023 (October 2022- August 2023), the United States Postal Inspection Service (USPIS) made 5,014 seizures, of drug substances in U.S. mail. That is an average of nearly 14 seizures per day. The most commonly seized substances were:

There are many employees and individuals at risk of exposure to these dangerous substances as mail is processed, handled, and delivered. Substances contained within those packages and envelopes are at risk of being dispersed on the surface of packaging materials, mail handling equipment, or in the air. In 2001, this type of threat was brought to light as anthrax attacks within the United States, delivered by ordinary mail, claimed the lives of five individuals. More recently, in November 2023, suspicious letters containing fentanyl were sent to U.S. voting centers and government buildings in six separate states.

Situation

A task force of federal, state, and local officers were investigating individuals and locations suspected of receiving packages containing illicit substances. They began surveillance on a house known to law enforcement to be a drop spot for packages that would later be collected by a neighbor.

After surveillance, officers set up a controlled delivery of the package to the residence. Officers conducted a stop of the vehicle and began to investigate the package. Suspecting the package contained a controlled substance, the officers used a K-9 which did not alert for any substance. This presented a challenge to law enforcement since they did not have a warrant to open the package. Officers had immediate access to optical chemical identification tools but were unable to utilize them since there was no visible material on the package.

Solution

The officers also had access to an MX908 and decided to test the outside of the package for trace residues of controlled substances. Officers swabbed the outside of the packaging focusing on the seals of the package, as these are the most likely areas for residues to collect. The swabs were analyzed using the MX908 Drug Hunter Mission Mode and returned a result of Cocaine. The presence of cocaine on the outside of the package allowed officers to obtain a warrant to open the package. The package was then opened and 2 lunchboxes were recovered, both containing 1 kilogram of cocaine.

Result

In the above scenario, the material inside the package was cocaine, which is not surprising given it was the most seized drug by the USPIS in FY23. However, it could have just as easily been fentanyl. Fentanyl in any form poses a major risk to health and safety due to its highly toxic nature. The average lethal dose of fentanyl and carfentanil are 2 milligrams and 0.02 milligrams respectively. These materials may be easily aerosolized while opening and handling packages or envelopes. In an envelope or package, fentanyl or its analogs could be found in various amounts and may pose a serious threat without being visible. The MX908 can identify fentanyl and its analogs at levels of tens of nanograms or 10,000 times less than the lethal dose of fentanyl and 100 times less than the lethal dose of carfentanil.

In a mail screening operation, this means that a user could quickly and easily determine whether a package or packages contain a dangerous substance by analyzing the air in a controlled processing area or by swabbing the outside of packages. Identification of trace drug substances, whether aerosolized or deposited on the outside of mail and packages, enables users to take appropriate actions and keep employees and first responders safe when handling these materials.

Sources

  • https://facts.usps.com/one-day/
  • https://www.uspis.gov/combating-illicit-drugs-in-the-mail
  • https://www.cnn.com/2023/11/09/politics/suspicious-lettersfentanyl-election-offices/index.html
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                    [post_content] => 

Cell therapy manufacturing continues to advance through innovation in bioreactor design, and the integration of process analytical technology (PAT) to monitor, control, and improve processes. Real-time and in-line and on-line monitoring of key metabolic parameters, such as glucose and lactate, enables improved control strategies for optimized cell culture. This, in turn, leads to more reliable and cost-effective manufacturing, ultimately helping make therapies more accessible to patients in need. Discover how the synergy between automated cell expansion systems and real-time analyzers revolutionizes cell culture processes.

This poster, developed in partnership with Quantum Flex and Terumo Blood and Cell Technologies, was featured at Advanced Therapies 2024.

[post_title] => Advancing Cell Therapy Manufacturing with Bioreactor and Bioprocess Control Solutions [post_excerpt] => Discover how the synergy between automated cell expansion systems and real-time analyzers revolutionizes cell culture processes. This poster was featured at Advanced Therapies 2024. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => advancing-cell-therapy-manufacturing-with-bioreactor-and-bioprocess-control-solutions [to_ping] => [pinged] => [post_modified] => 2024-11-25 16:11:50 [post_modified_gmt] => 2024-11-25 21:11:50 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26469 [menu_order] => 100 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 25884 [post_author] => 15 [post_date] => 2024-09-09 13:14:46 [post_date_gmt] => 2024-09-09 17:14:46 [post_content] =>

Advancements in bioprocess characterization technologies have progressed rapidly, broadening the range of readily accessible process information. While dissolved gases, pH, and temperature have been measurable in- or on-line for some time, crucial nutrients and metabolites are typically monitored via manual sampling and at- or off-line analysis.

This poster was a collaboration with Terumo Blood and Cell Technologies and was part of the poster program at the 2024 ISCT EU Conference.

[post_title] => Enhancing Cell and Gene Therapy Manufacturing Processes by In-line, On-line and At-line Bioprocess Analytical Technologies [post_excerpt] => The 908 Devices, on-, and in-line analytical solutions contribute to an enhanced understanding, characterization, and control of bioprocesses in development and manufacturing of cell and gene therapies. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => enhancing-cell-and-gene-therapy-manufacturing-processes-by-in-line-on-line-and-at-line-bioprocess-analytical-technologies [to_ping] => [pinged] => [post_modified] => 2024-09-09 13:14:46 [post_modified_gmt] => 2024-09-09 17:14:46 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25884 [menu_order] => 101 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 24564 [post_author] => 15 [post_date] => 2024-05-23 19:23:12 [post_date_gmt] => 2024-05-23 23:23:12 [post_content] => [post_title] => Optimization of Scalable rAAV Production for Gene Therapy – Utilizing At-Line Amino Acid Measurements for Bioprocess [post_excerpt] => The REBEL device enabled data-driven bioprocess development for rAAV manufacturing in HEK293 cells by accurately and precisely quantitating amino acids, leading to deeper process understanding. This poster was a collaboration with MIT and highlighted at the following 2024 Conferences-ASGCT, ISCT, ISCT EU and ESACT. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => optimization-of-scalable-raav-production-for-gene-therapy-utilizing-at-line-amino-acid-measurements-for-bioprocess [to_ping] => [pinged] => [post_modified] => 2024-09-09 10:08:26 [post_modified_gmt] => 2024-09-09 14:08:26 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24564 [menu_order] => 102 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 24562 [post_author] => 29 [post_date] => 2024-05-23 19:04:45 [post_date_gmt] => 2024-05-23 23:04:45 [post_content] => [post_title] => In-Line and On-Line Monitoring of Key Cell Culture Parameters for Robust Cell and Gene Therapy Bioprocess [post_excerpt] => The instant PAT implementation with MAVERICK, versatility, and sensitivity of MAVEN and point of need availability of amino acids analysis with REBEL, enable deeper knowledge and actionable information of Cell and GeneTherapy bioprocesses. Further, the devices informing power can be leveraged with the increasing sophistication of bioprocess metabolic models for predictive bioprocess optimization and control. This poster was highlighted at the 2024 ASGCT Conference. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => in-line-and-on-line-monitoring-of-key-cell-culture-parameters-for-robust-cell-and-gene-therapy-bioprocess [to_ping] => [pinged] => [post_modified] => 2024-07-29 09:55:27 [post_modified_gmt] => 2024-07-29 13:55:27 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24562 [menu_order] => 103 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 24537 [post_author] => 29 [post_date] => 2024-05-23 13:27:45 [post_date_gmt] => 2024-05-23 17:27:45 [post_content] => [post_title] => Microchip CE-MS Analysis of Nucleic Acids – From Characterization of Synthetic Oligonucleotides to Sequence Mapping of RNAs [post_excerpt] => This work will showcase how the ZipChip enables a simple and rapid workflow for the analysis of nucleic acids with noion-pairing reagents needed This poster was highlighted at the 2024 TIDES Conference. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => microchip-ce-ms-analysis-of-nucleic-acids-from-characterization-of-synthetic-oligonucleotides-to-sequence-mapping-of-rnas [to_ping] => [pinged] => [post_modified] => 2024-08-01 10:55:48 [post_modified_gmt] => 2024-08-01 14:55:48 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24537 [menu_order] => 104 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [5] => WP_Post Object ( [ID] => 23822 [post_author] => 29 [post_date] => 2024-03-25 09:32:04 [post_date_gmt] => 2024-03-25 13:32:04 [post_content] => [post_title] => Investigation of Drug-To-Antibody Ratio for FORCE Oligonucleotide Conjugates Using Microchip CE-MS [post_excerpt] => ZipChip microchip CE-MS resolves DAR species electrophoretically and enables generation of superior MS spectra. This poster was presented as a collaboration with Dyne Therapeutics at ASMS 2023 as poster WP045. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => investigation-of-drug-to-antibody-ratio [to_ping] => [pinged] => [post_modified] => 2024-07-29 09:58:16 [post_modified_gmt] => 2024-07-29 13:58:16 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23822 [menu_order] => 105 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [6] => WP_Post Object ( [ID] => 23824 [post_author] => 15 [post_date] => 2024-03-25 09:37:58 [post_date_gmt] => 2024-03-25 13:37:58 [post_content] => [post_title] => In-depth Characterization of Adeno-Associated Viruses using Microchip Capillary Electrophoresis Coupled with Mass Spectrometry [post_excerpt] => Rapid microchip CE-MS can be utilized for the in-depth characterization of AAVs including viral capsid protein analysis and peptide mapping. This poster was presented as a collaboration with NIBRT at ASMS 2023 as poster WP730. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => in-depth-characterization-of-adeno-associated-viruses [to_ping] => [pinged] => [post_modified] => 2024-03-25 09:56:23 [post_modified_gmt] => 2024-03-25 13:56:23 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23824 [menu_order] => 106 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [7] => WP_Post Object ( [ID] => 23966 [post_author] => 29 [post_date] => 2024-04-01 13:05:13 [post_date_gmt] => 2024-04-01 17:05:13 [post_content] => [post_title] => Rapid In-Depth Characterization of Biologics by Microchip CE-MS: mAbs, AAVs and Nucleic Acids [post_excerpt] => Microchip capillary electrophoresis (CE) coupled with mass spectrometry (MS) has revolutionized the characterization of therapeutic modalities in biopharmaceuticals. Here, we present the applications of an integrated workflow that couples the microfluidic CE system (ZipChip) with MS in characterization of biotherapeutics. This was poster A03 at BPS Europe 2024. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rapid-in-depth-characterization-of-biologics [to_ping] => [pinged] => [post_modified] => 2024-05-07 16:06:30 [post_modified_gmt] => 2024-05-07 20:06:30 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23966 [menu_order] => 107 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [8] => WP_Post Object ( [ID] => 23963 [post_author] => 29 [post_date] => 2024-04-01 12:35:51 [post_date_gmt] => 2024-04-01 16:35:51 [post_content] => [post_title] => Know Your Process: On-line and At-line Analytics for Upstream Bioprocess Key Nutrients [post_excerpt] => Bioprocess development requires analytics to monitor critical process parameters. This poster discusses two discuss two key technologies to characterize, optimize and control bioprocess. In 2024, this poster has been highlighted at BPI Europe and BPS Europe. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => know-your-process-on-line-and-at-line-analytics [to_ping] => [pinged] => [post_modified] => 2024-10-22 13:09:38 [post_modified_gmt] => 2024-10-22 17:09:38 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23963 [menu_order] => 108 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [9] => WP_Post Object ( [ID] => 23826 [post_author] => 15 [post_date] => 2024-03-25 10:02:00 [post_date_gmt] => 2024-03-25 14:02:00 [post_content] =>
Wistia video thumbnail
[post_title] => Raman-based In-line Monitoring of Key Process Parameters in Mammalian Bioprocesses without the Need for Chemometric Model Building [post_excerpt] => This poster describes a new technology called MAVERICK that uses Raman spectroscopy for continuous monitoring of mammalian cell cultures, specifically those using CHO and HEK293 cells. In 2024 this poster has been highlighted at BPI US West, BPS Europe, BPI Europe, BPI USA and most recently Advanced Therapies. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => raman-based-in-line-monitoring-of-key-process-parameters-in-mammalian [to_ping] => [pinged] => [post_modified] => 2024-11-18 15:35:31 [post_modified_gmt] => 2024-11-18 20:35:31 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23826 [menu_order] => 109 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [10] => WP_Post Object ( [ID] => 23828 [post_author] => 32 [post_date] => 2024-03-25 10:10:07 [post_date_gmt] => 2024-03-25 14:10:07 [post_content] => [post_title] => 5’ mRNA Analysis By Microchip CE-MS Using an Internal Cleavage Motif for RNase H Digestion [post_excerpt] => The subject of this poster was the investigation of an internal DNA motif to produce a shorter digestion product while simultaneously maintaining the length of the probe at 25nt for hybridization specificity. The shorter oligo results in easier detection using Microchip CE-MS approach. This poster was presented at ASMS 2023 as poster THP575. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => 5-mrna-analysis-by-microchip-ce-ms [to_ping] => [pinged] => [post_modified] => 2024-03-26 14:32:16 [post_modified_gmt] => 2024-03-26 18:32:16 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23828 [menu_order] => 110 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [11] => WP_Post Object ( [ID] => 23830 [post_author] => 15 [post_date] => 2024-03-25 10:15:07 [post_date_gmt] => 2024-03-25 14:15:07 [post_content] => [post_title] => Improved Performance of Phosphopeptides Characterization Using Online Capillary Electrophoresis Coupling with Ion Mobility Mass Spectrometry (CE-IM-MS) [post_excerpt] => This poster will highlight a novel strategy for characterization of therapeutic peptide that was developed based on microchip CE-MS pure liquid separation and ion mobility gas phase separation, combing with mass spectrometry identification. The poster was presented in collaboration with Ningbo University at ASMS 2023 as poster THP609. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => improved-performance-of-phosphopeptides-characterization [to_ping] => [pinged] => [post_modified] => 2024-03-25 10:15:12 [post_modified_gmt] => 2024-03-25 14:15:12 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23830 [menu_order] => 111 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [12] => WP_Post Object ( [ID] => 23832 [post_author] => 15 [post_date] => 2024-03-25 10:20:12 [post_date_gmt] => 2024-03-25 14:20:12 [post_content] => [post_title] => Amino Acid Quantitation in Over 50 Mammalian Cell Culture Media with an Integrated CE-MS Analyzer [post_excerpt] => Characterizing cell culture nutrients such as amino acids in growth media is critical for maximizing cell growth and improving key quality attributes of the cells. This poster was presented at ASMS 2023 as poster THP625. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => amino-acid-quantitation-in-over-50-mammalian-cell-culture-media [to_ping] => [pinged] => [post_modified] => 2024-08-01 14:18:02 [post_modified_gmt] => 2024-08-01 18:18:02 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23832 [menu_order] => 112 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [13] => WP_Post Object ( [ID] => 23820 [post_author] => 15 [post_date] => 2024-03-25 09:27:20 [post_date_gmt] => 2024-03-25 13:27:20 [post_content] => [post_title] => Rapid Identification of Conjugation Sites in Antibody Drug Conjugates Using Microchip Capillary Electrophoresis Coupled with Mass Spectrometry [post_excerpt] => CE/MS method is optimized with NISTmAb digest as a reference control. Good MS/MS coverage of NISTmAb is obtained with narrow peak width and fast separation. This poster was presented as a collaboration with Bruker at ASMS 2023 as poster WP041. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rapid-identification-of-conjugation-sites-in-antibody-drug [to_ping] => [pinged] => [post_modified] => 2024-03-25 09:28:04 [post_modified_gmt] => 2024-03-25 13:28:04 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23820 [menu_order] => 113 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [14] => WP_Post Object ( [ID] => 23818 [post_author] => 29 [post_date] => 2024-03-25 09:13:48 [post_date_gmt] => 2024-03-25 13:13:48 [post_content] => [post_title] => Conformation of Native Antibody-Drug Conjugate Charge Variants Revealed by Microchip Capillary Electrophoresis Coupled with Trapped Ion Mobility [post_excerpt] => The combination of microchip capillary electrophoresis and trapped ion mobility enables a rapid, informative method for native monoclonal antibody and antibody-drug conjugate charge variant analysis. This poster was a collaboration with Bruker and NIH and presented at ASMS 2023 as poster WP040. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => conformation-of-native-antibody-drug-conjugate-charge-variants [to_ping] => [pinged] => [post_modified] => 2024-05-07 14:29:50 [post_modified_gmt] => 2024-05-07 18:29:50 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23818 [menu_order] => 114 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [15] => WP_Post Object ( [ID] => 23798 [post_author] => 15 [post_date] => 2024-03-21 11:02:11 [post_date_gmt] => 2024-03-21 15:02:11 [post_content] => [post_title] => Fast Screening and Characterization of Therapeutic Peptide by Online Capillary Electrophoresis - Mass Spectrometry (CE-MS) [post_excerpt] => Presenting a novel strategy for characterization of therapeutic peptides was developed based on microchip CE-MS and linkage-specific derivatization. This poster was presented in collaboration with Ningbo University at ASMS 2023 as poster TP544. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => fast-screening-and-characterization-of-therapeutic-peptide [to_ping] => [pinged] => [post_modified] => 2024-03-21 11:02:12 [post_modified_gmt] => 2024-03-21 15:02:12 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23798 [menu_order] => 115 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [16] => WP_Post Object ( [ID] => 23796 [post_author] => 15 [post_date] => 2024-03-21 10:52:20 [post_date_gmt] => 2024-03-21 14:52:20 [post_content] => [post_title] => Continuing the Investigation of Microchip Capillary Electrophoresis Coupled with Mass Spectrometry in the Bottom-Up Characterization of Progressively Larger RNAs [post_excerpt] => Exploring the merits of capillary-zone electrophoresis (CZE)-mass spectrometry to analyze digestion mixtures of large RNAs and attain sequence information. This poster was presented as a collaboration with UConn and Bruker at ASMS 2023 and was poster TP532. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => continuing-the-investigation-of-microchip-capillary-electrophoresis [to_ping] => [pinged] => [post_modified] => 2024-08-01 14:18:20 [post_modified_gmt] => 2024-08-01 18:18:20 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23796 [menu_order] => 116 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [17] => WP_Post Object ( [ID] => 23794 [post_author] => 15 [post_date] => 2024-03-21 10:38:52 [post_date_gmt] => 2024-03-21 14:38:52 [post_content] => [post_title] => Determination of ATP, ADP, AMP, and Adenosine Levels by Microchip Capillary Electrophoresis Coupled with High Resolution Mass Spectrometry [post_excerpt] => In this study, we present a novel ZipChip coupled with a QEHF for adenosine nucleotide analysis. This poster was presented at ASMS 2023 as poster TP489. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => determination-of-atp-adp-amp-and-adenosine-levels [to_ping] => [pinged] => [post_modified] => 2024-08-01 14:18:43 [post_modified_gmt] => 2024-08-01 18:18:43 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23794 [menu_order] => 117 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [18] => WP_Post Object ( [ID] => 23789 [post_author] => 15 [post_date] => 2024-03-21 10:26:35 [post_date_gmt] => 2024-03-21 14:26:35 [post_content] => [post_title] => Amino Acid Quantitation of Cell Culture Media Matrices via an Integrated CE-MS Analyzer [post_excerpt] => Optimization of cell culture media and process conditions are critical for achieving optimal cell growth, productivity, and product quality. This poster was presented at ASMS 2023 as poster TP 398. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => amino-acid-quantitation-of-cell-culture-media [to_ping] => [pinged] => [post_modified] => 2024-03-21 10:33:40 [post_modified_gmt] => 2024-03-21 14:33:40 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23789 [menu_order] => 118 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [19] => WP_Post Object ( [ID] => 23787 [post_author] => 15 [post_date] => 2024-03-21 10:20:58 [post_date_gmt] => 2024-03-21 14:20:58 [post_content] => [post_title] => Sample to Result Workflow for the Investigation of Biosimilars vs Innovator Cetuximab by Charge Variant Analysis using Microchip CE-MS [post_excerpt] => This poster was presented in collaboration with Protein Metrics and highlights how the ZipChip coupled to HRMS provides a streamlined analytical approach to rapidly assess the heterogeneity of the investigated therapeutic proteins through the comprehensive interrogation of the different charge variants and their intact MS spectra. This poster was presented at ASMS 2023 as poster TP 384. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => sample-to-result-workflow-for-the-investigation-of-biosimilars-vs-innovator-cetuximab [to_ping] => [pinged] => [post_modified] => 2024-03-21 10:20:58 [post_modified_gmt] => 2024-03-21 14:20:58 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23787 [menu_order] => 119 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [20] => WP_Post Object ( [ID] => 23785 [post_author] => 15 [post_date] => 2024-03-21 10:15:48 [post_date_gmt] => 2024-03-21 14:15:48 [post_content] => [post_title] => Peptide Mapping Workflow for Direct Microchip CE-MS Analysis of Biopharmaceuticals [post_excerpt] => In this study we demonstrated the suitability of a modified digestion workflow for peptide mapping analysis via CE separation. This poster was presented at ASMS 2023 in collaboration with NIBRT. It was poster MP619. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => peptide-mapping-workflow-for-direct-microchip [to_ping] => [pinged] => [post_modified] => 2024-03-21 10:15:49 [post_modified_gmt] => 2024-03-21 14:15:49 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23785 [menu_order] => 120 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [21] => WP_Post Object ( [ID] => 23781 [post_author] => 15 [post_date] => 2024-03-21 09:57:40 [post_date_gmt] => 2024-03-21 13:57:40 [post_content] => [post_title] => Combining Capillary Electrophoresis and Trapped Ion Mobility Spectrometry Mass Spectrometry to Analyze Epitranscriptomic Marks Mediating Virus-Host Interactions in Infectious Diseases [post_excerpt] => This poster evaluates the merits of capillary-zone electrophoresis (CZE)-MS. This poster was presented at ASMS 2023 as a collaboration with UCONN. It was poster MP548. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => combining-capillary-electrophoresis-and-trapped-ion-mobility-spectrometry-mass-spectrometry [to_ping] => [pinged] => [post_modified] => 2024-03-21 09:57:41 [post_modified_gmt] => 2024-03-21 13:57:41 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23781 [menu_order] => 121 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [22] => WP_Post Object ( [ID] => 23779 [post_author] => 15 [post_date] => 2024-03-21 09:38:33 [post_date_gmt] => 2024-03-21 13:38:33 [post_content] => [post_title] => Use of Microchip Capillary Electrophoresis – Mass Spectrometry for Automated Rapid Measurement of Enzyme Reaction Kinetics [post_excerpt] => This approach allows rapid measurement of enzymatic cleavage dynamics in real time. It can be applied to almost any enzyme substrate reaction and is highly tolerable to various buffers, thanks to the CE Chip-MS configuration. This poster was presented at ASMS 2023 with collaborators as poster MP547. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => use-of-microchip-capillary-electrophoresis [to_ping] => [pinged] => [post_modified] => 2024-03-21 09:55:53 [post_modified_gmt] => 2024-03-21 13:55:53 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23779 [menu_order] => 122 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [23] => WP_Post Object ( [ID] => 24540 [post_author] => 29 [post_date] => 2024-05-23 13:58:57 [post_date_gmt] => 2024-05-23 17:58:57 [post_content] => [post_title] => Optimization of Scalable rAAV Production for Gene Therapy – Leveraging At-Line Amino AcidMeasurements for Bioprocess Modeling-Driven Approaches [post_excerpt] => Spent media analysis from an at-line analyzer, the REBEL, was used to further understanding of AAV production process and identify correlation between key nutrient consumptions and capsid titers in fed-batch and continuous processes. View our poster from the 2024 Advanced Manufacturing Cell and Gene Therapies Conference. This was poster 43. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => scalable-aav-production-gene-therapy [to_ping] => [pinged] => [post_modified] => 2024-08-01 12:39:26 [post_modified_gmt] => 2024-08-01 16:39:26 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24540 [menu_order] => 124 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [24] => WP_Post Object ( [ID] => 23776 [post_author] => 15 [post_date] => 2024-03-21 09:29:35 [post_date_gmt] => 2024-03-21 13:29:35 [post_content] => [post_title] => Rapid CE-MS Analysis of Released N-Glycan: Optimized Workflow for Direct CE Compatibility [post_excerpt] => N-glycan profiling is a critical step of biopharmaceuticals analysis as N-glycans play an important part in both activity and safety of monoclonal antibodies and other glycosylated biotherapeutics. This poster was presented at ASMS 2023 as poster MP291. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rapid-ce-ms-analysis-of-released-n-glycan [to_ping] => [pinged] => [post_modified] => 2024-03-21 09:35:32 [post_modified_gmt] => 2024-03-21 13:35:32 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23776 [menu_order] => 125 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [25] => WP_Post Object ( [ID] => 26486 [post_author] => 15 [post_date] => 2024-11-26 16:19:49 [post_date_gmt] => 2024-11-26 21:19:49 [post_content] =>

Process intensification in biomanufacturing often involves increasing cell densities and product titers, which can lead to increased glucose consumption and potential accumulation of toxic metabolites. High glucose concentrations can also negatively impact protein quality attributes. To address these challenges, we developed MAVERICK, a novel Raman-based PAT approach that enables real-time monitoring and control of CHO cell cultures without the need for prior model building. This versatile approach can be applied across various cell lines, media systems, reactor scales, and culture modes. By implementing a continuous dynamic feeding strategy guided by MAVERICK, we can enhance process performance and improve protein quality attributes like glycosylation, glycation, and charge variants.

MAVERICK, a novel Raman-based PAT technology, was showcased at the ECI Integrated Continuous Biomanufacturing Conference 2024. This technology allows for immediate monitoring of critical process parameters like glucose, lactate, and biomass without the need for extensive preliminary work or model building. By implementing a continuous glucose feeding strategy guided by MAVERICK, researchers were able to significantly improve process titer, cell-specific productivity, and protein quality attributes. This straightforward approach highlights the potential of MAVERICK to revolutionize biomanufacturing processes.

[post_title] => Novel Approach for Instant Implementation of Raman-based PAT with Integrated Real-Time Process Control [post_excerpt] => The innovative technology of Maverick allows for immediate monitoring of critical process parameters like glucose, lactate, and biomass without the need for extensive preliminary work or model building. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => novel-approach-for-instant-implementation-of-raman-based-pat-with-integrated-real-time-process-control [to_ping] => [pinged] => [post_modified] => 2024-11-26 16:19:49 [post_modified_gmt] => 2024-11-26 21:19:49 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26486 [menu_order] => 126 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [26] => WP_Post Object ( [ID] => 25226 [post_author] => 29 [post_date] => 2024-07-09 11:04:45 [post_date_gmt] => 2024-07-09 15:04:45 [post_content] =>

Understanding of cell culture metabolism in biologics manufacturing has increased tremendously in the past decade; however, the lack of feasible methods of high coverage, quantitative information on the interplay between nutrients and metabolites has hindered the efforts to fully characterize processes in the different biological phases. Several published models support cell growth phase but lack the kinetic information to be applicable to the phases that follow. We discuss a method for measuring hundreds of metabolites in dozens of pathways that streamlines sample preparation from spent media and cells, enables fast data-analysis times and supports quantitative analysis of key metabolites to gain far richer and more reliable data sources for process characterization, modelling and understanding. The method uses microchip CE/MS and incorporates stable isotope internal standards for both quantitation and migration time indexing. This work explores the information that can be obtained from the extracellular growth media and intracellular metabolites extracted from the CHO cells.

The poster was on display at Bioprocessing Summit, and ESACT #253 in 2024.

[post_title] => In-depth Metabolic Characterization at Different Phases of Cell Culture with a Turnkey CE-ESI-HRMS Workflow [post_excerpt] => Learn about a turnkey CE-MS metabolomics workflow solution used to characterize media metabolites and intracellular metabolites of CHO bioreactors. The poster was on display at Bioprocessing Summit, and ESACT #253 in 2024. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => correlation-of-soluble-metabolites-with-lactate-switch-observed-in-hek293-culture-using-novel-ce-ms-metabolomics-workflow [to_ping] => [pinged] => [post_modified] => 2024-11-25 16:13:49 [post_modified_gmt] => 2024-11-25 21:13:49 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25226 [menu_order] => 127 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [27] => WP_Post Object ( [ID] => 26149 [post_author] => 15 [post_date] => 2024-10-11 13:20:46 [post_date_gmt] => 2024-10-11 17:20:46 [post_content] =>

Advancements in bioprocess characterization technologies have progressed rapidly, broadening the range of readily accessible process information. While dissolved gases, pH, and temperature have been measurable in- or on-line for some time, crucial nutrients and metabolites are typically monitored via manual sampling and at- or off-line analysis. This poster was developed with Terumo Blood and Cell Technologies and was showcased at BPI USA and Advanced Therapies 2024.

[post_title] => Innovations in Analytical Technology for Cell & Gene Therapy Manufacturing [post_excerpt] => This poster highlights our at-, on-, and in-line analytical solutions that contribute to an enhanced understanding, characterization, and control of bioprocesses in the development and manufacturing of cell and gene therapies. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => innovations-in-analytical-technology-for-cell-gene-therapy-manufacturing [to_ping] => [pinged] => [post_modified] => 2024-11-18 15:32:59 [post_modified_gmt] => 2024-11-18 20:32:59 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26149 [menu_order] => 129 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [28] => WP_Post Object ( [ID] => 25218 [post_author] => 29 [post_date] => 2024-07-09 10:54:09 [post_date_gmt] => 2024-07-09 14:54:09 [post_content] =>

The introduction of the ZipChip Intact Antibodies Reagent Kit marked a significant milestone in the ZipChip portfolio, enabling the first tailored solution of charge variant analysis (CVA) of monoclonal antibodies on the CE-MS platform. However, there was room for enhancement in preserving the native conformation of the proteins under analysis, as well as in enhancing the separation between variant peaks. The next generation kits, the Native Antibodies Kit and Charge Variant TOF Kit, significantly improved peak separation and producing spectra more indicative of native protein structures. This was poster # TP642 at ASMS 2024.

[post_title] => Optimized Native Conditions for Charge Variant Analysis Using a Microfluidic CE-MS Platform Yield Higher Quality Data and Enables Analysis of Lower Titer Samples [post_excerpt] => Learn about the improvements made in the new Charge Variant Analysis kit, compared to the previous Intact Antibodies and Native Antibodies kits. ASMS 2024. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => optimized-native-conditions-for-charge-variant-analysis-using-a-microfluidic-ce-ms-platform-yield-higher-quality-data-and-enables-analysis-of-lower-titer-samples [to_ping] => [pinged] => [post_modified] => 2024-09-23 12:16:29 [post_modified_gmt] => 2024-09-23 16:16:29 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25218 [menu_order] => 130 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [29] => WP_Post Object ( [ID] => 25213 [post_author] => 29 [post_date] => 2024-07-09 10:28:00 [post_date_gmt] => 2024-07-09 14:28:00 [post_content] =>

As the field of bioprocessing continues to mature, there is a need for better analytics applied closer to the bioprocess. We have seen recent advancements in the technology used to measure small molecules within bioreactors (glucose/lactate, amino acids), but there is also a need to directly measure the critical quality attributes of the proteins being produced. To that end, we are assessing the ability of microfluidic CE-ESI-MS to perform charge variant - MS analysis of proteins pulled directly from a bioreactor. We know that excessive salt concentrations can cause band-broadening for this separation, so the key question is whether a desalting step is required, or if a simple dilute and shoot approach can work, and how much information can be obtained. Here we compare a simple dilute and shoot method to a method that buffer exchanges the sample before ZipChip analysis and demonstrates the use of this method for analysis of 4 different bioreactor growth conditions. This poster was on display at ASMS 2024 as poster # TP638.

[post_title] => Charge Variant Analysis of IgGs Directly from Cell Culture Supernatant Using Microfluidic CE-ESI-MS [post_excerpt] => This poster describes the application of Microfluidic CE-ESI-MS for analyzing protein charge variants directly from a bioreactor. It investigates the feasibility of a "dilute and shoot" approach compared to a buffer exchange method for sample preparation. ASMS 2024. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => charge-variant-analysis-of-iggs-directly-from-cell-culture-supernatant-using-microfluidic-ce-esi-ms [to_ping] => [pinged] => [post_modified] => 2024-09-23 12:20:01 [post_modified_gmt] => 2024-09-23 16:20:01 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25213 [menu_order] => 131 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [30] => WP_Post Object ( [ID] => 25249 [post_author] => 15 [post_date] => 2024-07-09 18:00:38 [post_date_gmt] => 2024-07-09 22:00:38 [post_content] =>

Raman spectroscopy offers relatively non-invasive access to the estimation of critical quality attributes and parameters in bioprocesses. Current approaches to predicting these parameters rely heavily on latent variable/regularized empirical calibration methods, with partial least-squares (PLS) being the most dominant. Although one advantage of these approaches is that they require zero detailed understanding of the underlying system (physics/chemistry/biology), there are several significant disadvantages to modelling bioprocess under these frameworks. This was poster #391 at ESACT 2024.

[post_title] => De Novo Approaches for Bioprocess Parameter Estimation Using Raman Spectroscopy [post_excerpt] => This research proposes a novel method for real-time bioprocess parameter prediction with de novo models using Raman spectroscopy. Unlike traditional methods, this approach requires no training data and offers a priori performance estimates. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => de-novo-approaches-for-bioprocess-parameter-estimation-using-raman-spectroscopy [to_ping] => [pinged] => [post_modified] => 2024-07-09 18:00:39 [post_modified_gmt] => 2024-07-09 22:00:39 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25249 [menu_order] => 137 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [31] => WP_Post Object ( [ID] => 25246 [post_author] => 15 [post_date] => 2024-07-09 14:48:37 [post_date_gmt] => 2024-07-09 18:48:37 [post_content] =>

The power of Raman spectroscopy for bioprocess monitoring is well-known , but the expertise required to develop ROBUST and SUSTAINABLE multivariate models is a massive impediment. Our goal was to develop an in-line device, termed MAVERICK, that provides immediate value for glucose, lactate and biomass estimation without the need for cumbersome model training/re-training with an ease-of-use similar to that of a pH probe. This was poster # 390 at ESACT 2024.

[post_title] => New Era of Real-time Bioprocess Monitoring and Control –Raman-based Direct Measurements with De Novo Model [post_excerpt] => MAVERICK offers real-time bioprocess monitoring of glucose, lactate, and biomass through a Raman-based sensor, eliminating the need for complex setup and training data. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => new-era-of-real-time-bioprocess-monitoring-and-control-raman-based-direct-measurements-with-de-novo-model [to_ping] => [pinged] => [post_modified] => 2024-07-09 14:48:38 [post_modified_gmt] => 2024-07-09 18:48:38 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25246 [menu_order] => 138 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [32] => WP_Post Object ( [ID] => 25245 [post_author] => 15 [post_date] => 2024-07-09 14:32:05 [post_date_gmt] => 2024-07-09 18:32:05 [post_content] =>

The biopharmaceutical industry is increasingly motivated to improve process control, understanding, and repeatability using process analytical technologies (PAT). More specifically, Raman-based optical, in-line measurement methods have shown promise as a way to monitor critical performance parameters, including glucose and lactate concentrations, in real-time. Recently, this has translated to the implementation of Raman-based glucose feeding strategies to modulate productivity and product quality in Chinese hamster ovary (CHO) cell cultures. The current work implements a novel Raman-based solution that does not require any chemometric models for glucose, lactate and biomass measurements. MAVERICK was directly, without any training in the specific bioprocess, deployed to dynamically control lactate feeding. We compared feeding strategies as means of modulating product quality and improving culture conditions, primarily through decreased ammonia accumulation. This was poster #358 at ESACT 2024 and was also highlighted at the Bioprocessing Summit 2024.

[post_title] => Raman-based Lactate Feeding Impact on Culture Characteristics and Product Quality in Mammalian Cell Cultures [post_excerpt] => This research explores Raman spectroscopy for real-time glucose monitoring and feeding strategies in CHO cell cultures, aiming to improve product quality. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => raman-based-lactate-feeding-impact-on-culture-characteristics-and-product-quality-in-mammalian-cell-cultures [to_ping] => [pinged] => [post_modified] => 2024-08-23 14:16:28 [post_modified_gmt] => 2024-08-23 18:16:28 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25245 [menu_order] => 139 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [33] => WP_Post Object ( [ID] => 25242 [post_author] => 15 [post_date] => 2024-07-09 14:23:13 [post_date_gmt] => 2024-07-09 18:23:13 [post_content] =>

Biologics production development for intensified processes aims to achieve desired product quality attributes and high productivity. Running multiple micro-bioreactors in parallel enables expedited optimization, but low microbioreactor volumes limit the media available for daily sampling for analysis. Cell culture media (CCM) optimization can be a lengthy and complex process involving multiple DOEs. Fast, at the point-of-need, analytical tools with only minimal sample consumption, are required to assess key-nutrient consumption and provide feedback to enable feed strategy optimization. This poster was created with CPI. In 2024 this poster has been highlighted at ESACT, the Bioprocessing Summit and BPI USA.

[post_title] => Data-driven Feed Strategy Optimization and Scale-up of mAb-expressing CHO Cell Line Bioprocess [post_excerpt] => This poster explores utilizing micro-bioreactors for expedited biologics production development, highlighting challenges with limited sample volume for media analysis and proposing real-time, point-of-need analytical tools for efficient CCM optimization. This poster was created with CPI. In 2024 this poster has been highlighted at ESACT, the Bioprocessing Summit and BPI USA. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => data-driven-feed-strategy-optimization-and-scale-up-of-mab-expressing-cho-cell-line-bioprocess [to_ping] => [pinged] => [post_modified] => 2024-10-02 13:40:29 [post_modified_gmt] => 2024-10-02 17:40:29 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25242 [menu_order] => 140 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [34] => WP_Post Object ( [ID] => 25192 [post_author] => 15 [post_date] => 2024-07-08 15:11:04 [post_date_gmt] => 2024-07-08 19:11:04 [post_content] =>

Through the work highlighted in this poster we found that when the manufactured cells are antigen-stimulated, CAR/VIPRa T-cells become significantly more energetic. In contrast, CAR T-cells become less energetic and more glycolytic, which are known features of T-cell exhaustion. Further, metabolic assessment with multiple methods produced findings that correlated with this assessment, such oxygen consumption and certain amino acid levels in spent media. Finally, CAR T-cell activity, potency, and cytotoxicity assessments showed a correlation with anti-tumor activity. Together, this work demonstrates that distinct metabolic features allow CAR/VIPRa T cells, when antigen-stimulated, to have enhanced functions against tumors. Developed in partnership with Emory University and the Winship Cancer Institute, this poster has made waves at the 2024 ISCT & ISCT EU Conference, the ESACT Conference, and Advanced Therapies 2024.

[post_title] => Spent Media Analysis Aids in Determining Metabolic Mechanisms of Superior CAR T-Cell Products [post_excerpt] => As the use of CAR T-cell therapies advances, testing different CAR T-cells, and associating metabolic characteristics to well-performing, desired phenotypes of CAR T-cells enables optimization of CAR constructs and manufacturing processes. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => spent-media-analysis-aids-in-determining-metabolic-mechanisms-of-superior-car-t-cell-products [to_ping] => [pinged] => [post_modified] => 2024-11-18 15:37:35 [post_modified_gmt] => 2024-11-18 20:37:35 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25192 [menu_order] => 141 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [35] => WP_Post Object ( [ID] => 25189 [post_author] => 15 [post_date] => 2024-07-08 14:47:24 [post_date_gmt] => 2024-07-08 18:47:24 [post_content] =>

This poster highlights the HEK-mediated adeno-associated virus (AAV) production process and the development of an open-source production platform incorporating a chemically defined serum-free medium. Initial attempts using an open-source CHO-medium resulted in cell aggregation, slow growth, and an inability to transfect and produce AAV. Therefore, we explored creating an HEK-friendly medium and process conducive to healthy cell growth, transfection, and vector production. Nutrient consumption rates were studied to elucidate metabolic activity associated with AAV production. This poster was #835 at ISCT 2024

[post_title] => Open-sourced Production Platform for Raav in HEK Data-driven Cell Culture Media Optimization [post_excerpt] => This poster highlights the HEK-mediated adeno-associated virus (AAV) production process and the development of an open-source production platform incorporating a chemically defined serum-free medium. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => open-sourced-production-platform-for-raav-in-hek-data-driven-cell-culture-media-optimization [to_ping] => [pinged] => [post_modified] => 2024-07-08 14:47:25 [post_modified_gmt] => 2024-07-08 18:47:25 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25189 [menu_order] => 142 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [36] => WP_Post Object ( [ID] => 23438 [post_author] => 15 [post_date] => 2024-02-20 17:24:46 [post_date_gmt] => 2024-02-20 22:24:46 [post_content] => [post_title] => Improving Cell and Gene Therapy Manufacturing Processes by Automated On-line and In-line Bioprocess Analytical Technologies [post_excerpt] => Recent advances in cell and gene therapy bioprocess analytical technology regimes, approaches to de novo analytical modeling/calibration of these systems, and how their informing power can be leveraged with the increasing sophistication of bioprocess metabolic models for predictive bioprocess optimization. View our poster from the 2024 Advanced Manufacturing Cell and Gene Therapies Conference. This was poster 29. This poster was also on display as #843 at ISCT 2024. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => improving-cell-gene-therapy-manufacturing [to_ping] => [pinged] => [post_modified] => 2024-07-08 13:01:02 [post_modified_gmt] => 2024-07-08 17:01:02 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23438 [menu_order] => 143 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [37] => WP_Post Object ( [ID] => 23435 [post_author] => 29 [post_date] => 2024-02-20 17:15:13 [post_date_gmt] => 2024-02-20 22:15:13 [post_content] => [post_title] => Amino Acid Analysis Indicates Metabolic Differences in Multi-Cytokine Backpack - Manufactured CAR T-Cells [post_excerpt] => Novel reagents that aid in the consistent manufacturing of Novel reagents that aid in consistent manufacturing of CAR T-cells with well-defined phenotypes are needed to improve treatment outcomes in patients. View poster #17 from the 2024 Advanced Manufacturing Cell and Gene Therapies Conference. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => multi-cytokine-backpack-car-t-cells [to_ping] => [pinged] => [post_modified] => 2024-08-01 11:11:58 [post_modified_gmt] => 2024-08-01 15:11:58 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23435 [menu_order] => 144 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [38] => WP_Post Object ( [ID] => 23432 [post_author] => 15 [post_date] => 2024-02-20 17:03:02 [post_date_gmt] => 2024-02-20 22:03:02 [post_content] => [post_title] => Optimization of Cell Culture Media and Culture Conditions for HEK293 for Improved Cell Growth and Reduced Cell Clumping for the Effective Production of Viral Vectors [post_excerpt] => This study demonstrates the power of at-line cell culture analyzers such as the REBEL to gain process understanding quickly to adjust media components for improved cell culture performance. View our poster from the 2024 Advanced Manufacturing Cell and Gene Therapies Conference. This was poster 18. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => improved-cell-growth-production-viral-vectors [to_ping] => [pinged] => [post_modified] => 2024-03-21 09:09:37 [post_modified_gmt] => 2024-03-21 13:09:37 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=23432 [menu_order] => 145 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [39] => WP_Post Object ( [ID] => 7689 [post_author] => 29 [post_date] => 2023-02-27 11:46:37 [post_date_gmt] => 2023-02-27 16:46:37 [post_content] => [post_title] => Automated Glucose Feeding Based On Online Glucose And Lactate Measurements [post_excerpt] => This poster note describes an automated control strategy for cell growth and biologics production. It leverages MAVEN, a reliable, easy-to-operate, online (sample-free) device for monitoring of glucose and lactate. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => maven-poster-bpi-west-2023 [to_ping] => [pinged] => [post_modified] => 2024-07-29 09:59:39 [post_modified_gmt] => 2024-07-29 13:59:39 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7689 [menu_order] => 146 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [40] => WP_Post Object ( [ID] => 7158 [post_author] => 15 [post_date] => 2022-11-30 20:16:00 [post_date_gmt] => 2022-12-01 01:16:00 [post_content] => [post_title] => Process Optimization by the Use of Substrate Feeding Strategies [post_excerpt] => Online glucose monitoring is possible by using Trace C2 Control system. Feed control without online glucose monitoring causes acetate formation due to overflow metabolism. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-poster-process-optimization-by-the-use-of-substrate-feeding-strategies [to_ping] => [pinged] => [post_modified] => 2024-04-03 18:38:25 [post_modified_gmt] => 2024-04-03 22:38:25 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7158 [menu_order] => 147 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [41] => WP_Post Object ( [ID] => 7156 [post_author] => 15 [post_date] => 2022-11-30 20:03:35 [post_date_gmt] => 2022-12-01 01:03:35 [post_content] => [post_title] => Optimized Fed-Batch Fermentation by Use of Online Glucose Measurement [post_excerpt] => This poster presentation features an integrated multivariate glucose measuring tool combined with software solutions which allow different types of feeding-strategies. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-poster-optimized-fed-batch [to_ping] => [pinged] => [post_modified] => 2024-04-03 18:40:24 [post_modified_gmt] => 2024-04-03 22:40:24 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7156 [menu_order] => 148 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [42] => WP_Post Object ( [ID] => 7153 [post_author] => 15 [post_date] => 2022-11-30 19:53:12 [post_date_gmt] => 2022-12-01 00:53:12 [post_content] => [post_title] => High Frequency Glucose and Lactate Measurements in Multi-Bioreactor Vessels [post_excerpt] => TRACE C2 is an online analyzer for monitoring and controlling glucose and lactate concentrations in bioreactors. With the extension M4 it is possible to monitor Glucose and Lactate in up to four simultaneous bioprocesses. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-poster-high-frequency-glucose-and-lactate [to_ping] => [pinged] => [post_modified] => 2024-04-03 18:42:31 [post_modified_gmt] => 2024-04-03 22:42:31 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7153 [menu_order] => 149 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [43] => WP_Post Object ( [ID] => 7151 [post_author] => 15 [post_date] => 2022-11-30 19:44:36 [post_date_gmt] => 2022-12-01 00:44:36 [post_content] => [post_title] => Online-Controlling of Glucose in Cultivations and Fermentations [post_excerpt] => TRACE C2 Control is a new online analyzer for monitoring and controlling of glucose concentrations in bioprocesses. In disturbance reaction experiments and in an E.coli fermentation it can be successfully shown that a reliable control is possible. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-poster-online-controlling-of-glucose [to_ping] => [pinged] => [post_modified] => 2024-04-03 18:43:23 [post_modified_gmt] => 2024-04-03 22:43:23 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7151 [menu_order] => 150 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [44] => WP_Post Object ( [ID] => 7149 [post_author] => 15 [post_date] => 2022-11-30 19:33:56 [post_date_gmt] => 2022-12-01 00:33:56 [post_content] => [post_title] => Implementation of a New Method for Online Glucose Control in a 10L CHO Bioprocess [post_excerpt] => This poster shows how glucose concentration can be directly measured based on an enzymatic reaction. This method is then used to control the glucose level in a fed-batch fermentation at a constant level. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-poster-online-glucose-control [to_ping] => [pinged] => [post_modified] => 2024-04-03 19:14:31 [post_modified_gmt] => 2024-04-03 23:14:31 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7149 [menu_order] => 151 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [45] => WP_Post Object ( [ID] => 7144 [post_author] => 15 [post_date] => 2022-11-30 19:05:04 [post_date_gmt] => 2022-12-01 00:05:04 [post_content] => [post_title] => Single-Use Bioreactor for High Density Bacterial Fermentation [post_excerpt] => Glucose measurement is performed on-line using the TRACE C2 analyzer. This allows to follow-up glucose uptake rate and monitor fed batch culture with retro-control on the glucose pump such as maintain glucose level at predefined set point. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => trace-c2-poster-single-use-bioreactor [to_ping] => [pinged] => [post_modified] => 2024-04-03 18:45:30 [post_modified_gmt] => 2024-04-03 22:45:30 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=7144 [menu_order] => 152 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [46] => WP_Post Object ( [ID] => 6534 [post_author] => 20 [post_date] => 2022-09-22 15:09:32 [post_date_gmt] => 2022-09-22 19:09:32 [post_content] => [post_title] => Optimization of Scalable rAAV Production for Gene Therapy [post_excerpt] => This poster showcases spent media analysis leveraging REBEL, which requires only 10 μL per sample and 10 minutes analysis time. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-ps-13 [to_ping] => [pinged] => [post_modified] => 2023-12-26 10:04:40 [post_modified_gmt] => 2023-12-26 15:04:40 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6534 [menu_order] => 178 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [47] => WP_Post Object ( [ID] => 6530 [post_author] => 29 [post_date] => 2022-09-22 15:04:14 [post_date_gmt] => 2022-09-22 19:04:14 [post_content] => [post_title] => Empowering Process Optimization for a mAb-Expressing CHO Cell Line [post_excerpt] => Coupling miniature mass spectrometry (MS) with microchip capillary electrophoresis (CE) fulfills an unmet need: simple, rapid at-line nutrient quantitation. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => rebel-ps-14 [to_ping] => [pinged] => [post_modified] => 2024-08-01 12:20:03 [post_modified_gmt] => 2024-08-01 16:20:03 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6530 [menu_order] => 181 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [48] => WP_Post Object ( [ID] => 6117 [post_author] => 20 [post_date] => 2022-06-11 02:59:33 [post_date_gmt] => 2022-06-11 06:59:33 [post_content] => [post_title] => Bottom-Up Analysis of Progressively Larger RNAs by CZE-MS and CZE-MS/MS [post_excerpt] => In this poster from ASMS 2022, researchers from University of Connecticut and Bruker showed that capillary zone electrophoresis performed on a chip proved to be an effective alternative to liquid chromatography as a front-end separation system to analyze both pure samples and complex digestion mixtures of nucleic acids. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-uconn [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:43:57 [post_modified_gmt] => 2023-12-26 17:43:57 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6117 [menu_order] => 193 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [49] => WP_Post Object ( [ID] => 6115 [post_author] => 20 [post_date] => 2022-06-11 02:52:58 [post_date_gmt] => 2022-06-11 06:52:58 [post_content] => [post_title] => Multi-level Expeditious Characterization of Adeno-associated Virus (AAV) Capsid Proteins Using ZipChip Microfluidic CE Coupled with HRMS [post_excerpt] => In this poster from ASMS 2022, scientists from Thermo Fisher Scientific and 908 Devices present a novel approach using microchip CE-MS for the characterization of AAVs. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-thermo [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:42:52 [post_modified_gmt] => 2023-12-26 17:42:52 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6115 [menu_order] => 194 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [50] => WP_Post Object ( [ID] => 6114 [post_author] => 29 [post_date] => 2022-06-11 02:42:23 [post_date_gmt] => 2022-06-11 06:42:23 [post_content] => [post_title] => A Sensitive and High-Throughput Assay for Analyzing Peptide Exchanged MHCl by High-Resolution Native CZE-MS [post_excerpt] => In this poster from ASMS 2022, researchers from Genentech describe a sensitive and high-throughput assay using capillary-zone electrophoresis coupled to a high-resolution mass spectrometer for characterizing peptide-exchanged MHCI under native conditions. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-genentech [to_ping] => [pinged] => [post_modified] => 2024-06-26 15:34:54 [post_modified_gmt] => 2024-06-26 19:34:54 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6114 [menu_order] => 195 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [51] => WP_Post Object ( [ID] => 6113 [post_author] => 20 [post_date] => 2022-06-11 02:37:28 [post_date_gmt] => 2022-06-11 06:37:28 [post_content] => [post_title] => Combining μSPE ZipChip CE with PRM-LIVE on a timsTOF Pro for Warp-speed Selectivity Profiling of Deubiquitinase (DUB) Small Molecule Inhibitors [post_excerpt] => In this ASMS 2022 poster, researchers from Dana Farber Cancer Institute and Harvard Medical School developed a ZipChip-based method for facilitating high-throughput identification of new small molecule inhibitors. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-dana-farber [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:41:30 [post_modified_gmt] => 2023-12-26 17:41:30 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6113 [menu_order] => 196 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [52] => WP_Post Object ( [ID] => 6112 [post_author] => 20 [post_date] => 2022-06-11 02:30:52 [post_date_gmt] => 2022-06-11 06:30:52 [post_content] => [post_title] => Microchip CE-MS Analysis of Sialylated N-glycan Linkage Isomers [post_excerpt] => In this ASMS 2022 poster, Fudan University researchers show a ZipChip-based strategy for qualitative and quantitative analysis of sialylated N-glycan linkage isomers was developed. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-fudan [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:40:53 [post_modified_gmt] => 2023-12-26 17:40:53 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6112 [menu_order] => 197 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [53] => WP_Post Object ( [ID] => 6111 [post_author] => 20 [post_date] => 2022-06-11 02:25:34 [post_date_gmt] => 2022-06-11 06:25:34 [post_content] => [post_title] => CE-MS of Oligonucleotides using a ZipChip [post_excerpt] => This ASMS 2022 poster from Boehringer Ingelheim explores the use of ZipChip coupled to a high resolution mass spectrometer as an orthogonal method to chromatography for oligonucleotide analysis. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-boehringer [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:39:52 [post_modified_gmt] => 2023-12-26 17:39:52 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6111 [menu_order] => 198 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [54] => WP_Post Object ( [ID] => 6109 [post_author] => 15 [post_date] => 2022-06-11 02:14:51 [post_date_gmt] => 2022-06-11 06:14:51 [post_content] => [post_title] => Rapid Characterization of Oligos and Related Impurities Using Microchip CE-MS without Ion-pairing Reagents [post_excerpt] => This poster from ASMS 2022 describes a simple & fast method for oligonucleotide characterizations using a Microchip CE-MS platform. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-kulkarni [to_ping] => [pinged] => [post_modified] => 2024-08-01 14:18:58 [post_modified_gmt] => 2024-08-01 18:18:58 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6109 [menu_order] => 199 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [55] => WP_Post Object ( [ID] => 6110 [post_author] => 15 [post_date] => 2022-06-11 02:20:24 [post_date_gmt] => 2022-06-11 06:20:24 [post_content] => [post_title] => Glycosylation Profiling of mAB Subunits with CZE-MS [post_excerpt] => This ASMS 2022 poster from Bruker shows ZipChip coupled with high resolution mass spectrometry providing charge-based selectivity which can assist with glycoforms separation. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-glycosylation-profiling [to_ping] => [pinged] => [post_modified] => 2024-08-01 14:19:13 [post_modified_gmt] => 2024-08-01 18:19:13 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6110 [menu_order] => 200 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [56] => WP_Post Object ( [ID] => 6105 [post_author] => 20 [post_date] => 2022-06-10 20:16:47 [post_date_gmt] => 2022-06-11 00:16:47 [post_content] => [post_title] => Pushing the Boundaries of Speed and Sensitivity in Proteomics [post_excerpt] => To overcome sample loading limitations in CE-MS, the poster authors engineered a 1 mm SPE bed within the chip geometry, allowing 100-fold improvements in concentration sensitivity limit for CE-MS. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-thompson [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:37:31 [post_modified_gmt] => 2023-12-26 17:37:31 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6105 [menu_order] => 201 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [57] => WP_Post Object ( [ID] => 6104 [post_author] => 20 [post_date] => 2022-06-10 19:14:29 [post_date_gmt] => 2022-06-10 23:14:29 [post_content] => [post_title] => A Broad Application of Migration Time Indexing and Metabolite Libraries to Evaluate Quantitative Coverage in Microchip CE-MS Metabolomics [post_excerpt] => In the field of metabolomics, microchip capillary electrophoresis (mCE) has a number of potential advantages over traditional liquid chromatography (LC), including higher throughput due to decreased separation times, increased separation efficiency, and lower required sample volumes. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-asms2022-metabolomics-raiche [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:36:48 [post_modified_gmt] => 2023-12-26 17:36:48 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=6104 [menu_order] => 202 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [58] => WP_Post Object ( [ID] => 5998 [post_author] => 20 [post_date] => 2022-05-09 12:26:20 [post_date_gmt] => 2022-05-09 16:26:20 [post_content] => [post_title] => A Microchip CE-MS Based End-to-End Solution for the Analysis of Synthetic Oligonucleotides [post_excerpt] => This poster showcases a workflow using microchip CE-MS that is coupled with a vendor-neutral informatics platform as a complete solution for the analysis of synthetic oligos. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => a-microchip-ce-ms-based-end-to-end-solution-for-the-analysis-of-synthetic-oligonucleotides [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:35:39 [post_modified_gmt] => 2023-12-26 17:35:39 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=5998 [menu_order] => 218 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [59] => WP_Post Object ( [ID] => 4938 [post_author] => 20 [post_date] => 2021-11-05 18:59:31 [post_date_gmt] => 2021-11-05 22:59:31 [post_content] => [post_title] => Microchip CE-MS with Integrated Solid Phase Extraction [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-microchip-cebrms-with-integrated-solid-phase-extraction [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:34:50 [post_modified_gmt] => 2023-12-26 17:34:50 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=4938 [menu_order] => 286 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [60] => WP_Post Object ( [ID] => 4926 [post_author] => 20 [post_date] => 2021-11-05 18:34:01 [post_date_gmt] => 2021-11-05 22:34:01 [post_content] => [post_title] => Microchip CE-MS of Oligonucleotides: What Can It Separate? [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip-poster-microchip-ce-ms-of-oligonucleotides-what-can-it-separate [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:34:32 [post_modified_gmt] => 2023-12-26 17:34:32 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=4926 [menu_order] => 287 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [61] => WP_Post Object ( [ID] => 788 [post_author] => 20 [post_date] => 2017-10-05 18:10:30 [post_date_gmt] => 2017-10-05 22:10:30 [post_content] => [post_title] => Fast Chip-CEMS for Characterization of Protein/PTM Changes [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => poster-fast-chip-cems-characterization-proteinptm-changes [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:20:09 [post_modified_gmt] => 2023-12-26 17:20:09 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/poster-fast-chip-cems-characterization-proteinptm-changes/ [menu_order] => 370 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [62] => WP_Post Object ( [ID] => 786 [post_author] => 20 [post_date] => 2017-10-05 17:52:35 [post_date_gmt] => 2017-10-05 21:52:35 [post_content] => [post_title] => Combined Top-down and Bottom-up Proteomics [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => poster-combined-top-bottom-proteomics-using-capillary-electrophoresis-mass-spectrometry [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:19:21 [post_modified_gmt] => 2023-12-26 17:19:21 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/poster-combined-top-bottom-proteomics-using-capillary-electrophoresis-mass-spectrometry/ [menu_order] => 374 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [63] => WP_Post Object ( [ID] => 790 [post_author] => 20 [post_date] => 2017-10-05 18:20:04 [post_date_gmt] => 2017-10-05 22:20:04 [post_content] => [post_title] => ZipChip for Glycomics and Glycoproteomics [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => poster-microfluidic-capillary-electrophoresis-mass-spectrometry-glycomics-glycoproteomics [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:20:31 [post_modified_gmt] => 2023-12-26 17:20:31 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/poster-microfluidic-capillary-electrophoresis-mass-spectrometry-glycomics-glycoproteomics/ [menu_order] => 386 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [64] => WP_Post Object ( [ID] => 1092 [post_author] => 20 [post_date] => 2020-07-29 17:22:01 [post_date_gmt] => 2020-07-29 21:22:01 [post_content] => [post_title] => Fast and Efficient Biopharmaceutical Characterization [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => zipchip_poster_2019-cesi-symposium [to_ping] => [pinged] => [post_modified] => 2023-12-26 12:26:08 [post_modified_gmt] => 2023-12-26 17:26:08 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/resource/zipchip_poster_2019-cesi-symposium/ [menu_order] => 402 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [65] => WP_Post Object ( [ID] => 1078 [post_author] => 20 [post_date] => 2020-06-19 20:21:47 [post_date_gmt] => 2020-06-20 00:21:47 [post_content] => [post_title] => Characterization of charge heterogeneity of mAb [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => 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Cell therapy manufacturing continues to advance through innovation in bioreactor design, and the integration of process analytical technology (PAT) to monitor, control, and improve processes. Real-time and in-line and on-line monitoring of key metabolic parameters, such as glucose and lactate, enables improved control strategies for optimized cell culture. This, in turn, leads to more reliable and cost-effective manufacturing, ultimately helping make therapies more accessible to patients in need. Discover how the synergy between automated cell expansion systems and real-time analyzers revolutionizes cell culture processes.

This poster, developed in partnership with Quantum Flex and Terumo Blood and Cell Technologies, was featured at Advanced Therapies 2024.

[post_title] => Advancing Cell Therapy Manufacturing with Bioreactor and Bioprocess Control Solutions [post_excerpt] => Discover how the synergy between automated cell expansion systems and real-time analyzers revolutionizes cell culture processes. This poster was featured at Advanced Therapies 2024. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => advancing-cell-therapy-manufacturing-with-bioreactor-and-bioprocess-control-solutions [to_ping] => [pinged] => [post_modified] => 2024-11-25 16:11:50 [post_modified_gmt] => 2024-11-25 21:11:50 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=26469 [menu_order] => 100 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 79 [max_num_pages] => 0 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => 1 [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => 1 [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => 1 [query_vars_hash:WP_Query:private] => 989dd663d4dda53cb7a08238d022b246 [query_vars_changed:WP_Query:private] => 1 [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )

Posters

Advancing Cell Therapy Manufacturing with Bioreactor and Bioprocess Control Solutions

Discover how the synergy between automated cell expansion systems and real-time analyzers revolutionizes cell culture processes. This poster was featured at Advanced Therapies 2024.

Enhancing Cell and Gene Therapy Manufacturing Processes by In-line, On-line and At-line Bioprocess Analytical Technologies

The 908 Devices, on-, and in-line analytical solutions contribute to an enhanced understanding, characterization, and control of bioprocesses in development and manufacturing of cell and gene therapies.

Optimization of Scalable rAAV Production for Gene Therapy – Utilizing At-Line Amino Acid Measurements for Bioprocess

The REBEL device enabled data-driven bioprocess development for rAAV manufacturing in HEK293 cells by accurately and precisely quantitating amino acids, leading to deeper process understanding. This poster was a collaboration with MIT and highlighted at the following 2024 Conferences-ASGCT, ISCT, ISCT EU and ESACT.

In-Line and On-Line Monitoring of Key Cell Culture Parameters for Robust Cell and Gene Therapy Bioprocess

The instant PAT implementation with MAVERICK, versatility, and sensitivity of MAVEN and point of need availability of amino acids analysis with REBEL, enable deeper knowledge and actionable information of Cell and GeneTherapy bioprocesses. Further, the devices informing power can be leveraged with the increasing sophistication of bioprocess metabolic models for predictive bioprocess optimization and control. This poster was highlighted at the 2024 ASGCT Conference.

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                    [post_date] => 2024-09-09 09:44:44
                    [post_date_gmt] => 2024-09-09 13:44:44
                    [post_content] => 

908 Devices expanded its chemical detection capabilities by acquiring RedWave Technology, combining its high-pressure mass spectrometry (HPMS) expertise with RedWave’s advanced Fourier-transform infrared (FTIR) technology. This acquisition creates a more comprehensive solution for detecting and identifying chemicals across various scenarios, from field forensics to hazardous material response. The move also opens new opportunities for cross-selling, shared training, and customer support, positioning 908 Devices as a key player in both public safety and military markets.

Article Source: CBRNe World

[post_title] => Catching a RedWave [post_excerpt] => Explore how 908 Devices' acquisition of RedWave Technology is revolutionizing chemical detection with advanced mass spectrometry and FTIR solutions, expanding capabilities for public safety and military applications. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => catching-a-redwave [to_ping] => [pinged] => [post_modified] => 2024-10-09 16:14:57 [post_modified_gmt] => 2024-10-09 20:14:57 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=25881 [menu_order] => 272 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [5] => WP_Post Object ( [ID] => 25481 [post_author] => 29 [post_date] => 2024-08-06 17:33:09 [post_date_gmt] => 2024-08-06 21:33:09 [post_content] =>

The novel 13C tracer-based metabolomics method using microfluidic capillary electrophoresis-mass spectrometry (CE-MS) enables rapid and accurate analysis of isotopomer patterns in proteinogenic amino acids from minimal sample sizes, revealing central carbon metabolism and amino acid biosynthesis pathways in microbes such as Methanothermobacter thermautotrophicus. This method, utilizing a ZipChip CE system and an Orbitrap Fusion Tribrid mass spectrometer, demonstrated high sensitivity and precision, detecting metabolic pathways and fluxes even under biomass-restricted conditions. The approach also highlights the presence of alternative enzymes and biosynthesis pathways not captured by existing public databases, thus enhancing the prediction and understanding of microbial metabolic and genetic capabilities.

[post_title] => Development of a rapid and highly accurate method for 13C tracer-based metabolomics and its application on a hydrogenotrophic methanogen [post_excerpt] => Yuto Fukuyama, et al. ISME Communications, 2024. The novel 13C tracer-based metabolomics method using ZipChip CE-MS provides highly accurate and sensitive identification of central carbon metabolism and amino acid biosynthesis pathways, enhancing our understanding of microbial metabolic capabilities and revealing previously unrecognized alternative enzymes. 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Download Safety Data Sheet (SDS) for documentation related to the properties of each chemical in the product; the physical, health, and environmental health hazards; protective measures; and safety precautions for handling, storing, and transporting the product.  For products where multiple SDS are available, please check the part number and concentration.

Buffer

SDS Buffer salt mixture Glu Lac for cell culture buffer 850.300.136
SDS Buffer solution Glu Lac cell culture 850.300.135
SDS Transport buffer ready to use Ethanol Methanol 850.300.625
SDS Transport buffer ready to use Glucose Lactate 850.300.125

Calibration Standards—Ethanol

SDS Calibration standard Ethanol 850.302.004 [0.5 g/L]
SDS Calibration standard Ethanol 850.302.001 [2 g/L]
SDS Calibration standard Ethanol 850.302.002 [4 g/L]
SDS Calibration standard Ethanol 850.302.005 [40 g/L]

Calibration Standards—Glucose & Lactate

SDS MAVEN Calibration standard Glu_Lac 850.306.000
SDS Calibration standard Glucose Lactate 850.305.000 [0.5glu 0.25lac]
SDS Calibration standard Glucose Lactate 850.305.001 [1glu 0.5lac]
SDS Calibration standard Glucose Lactate 850.305.002 [2glu 1lac]
SDS Calibration standard Glucose Lactate 850.305.003 [4glu 2lac]
SDS Calibration standard Glucose Lactate 850.305.004 [10glu 5lac]
SDS Calibration standard Glucose Lactate 850.305.005 [20glu 10lac]
SDS Calibration standard Glucose Lactate 850.305.006 [0.1glu 0.05lac]

Calibration Standards—Methanol

SDS Calibration standard Methanol 850.301.002 [0.2 g/L]
SDS Calibration standard Methanol 850.301.004 [1 g/L]
SDS Calibration standard Methanol 850.301.005 [5 g/L]
SDS Calibration standard Methanol 850.301.008 [20 g/L]

Cleaning Solution

SDS Cleaning solution GLU LA 850.300.700_710
SDS Cleaning solution Ethanol Methanol 850.300.701_711

Hardware

SDS Diffusion membrane ET ME 860.211.036
SDS Diffusion membrane GLU LA cell resist 860.211.049_ 045_043__048_050_055_056_057_058
SDS Enzyme reactor AOD 811.100.120_811.100.102
SDS Glucose Oxidase, Lactate Oxidase (GOD, LOD) Sensor
SDS Installation kit diffusion probe LUER
SDS MAVEN Tubing set without sensor Diffusion Glucose Lactate
SDS Sensor set Diffusion Glucose Lactate
SDS Single-use diffusion flow cell
SDS Tubing set Diffusion Ethanol Methanol
SDS Tubing set Diffusion Glucose Lactate
SDS Tubing set Filtration Ethanol Methanol
SDS Tubing set Filtration Glucose Lactate
SDS Tubing set without sensor Diffusion Glucose Lactate TRACE

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Download this Safety Data Sheet (SDS) for documentation related to the properties of each chemical in the product; the physical, health, and environmental health hazards; protective measures; and safety precautions for handling, storing, and transporting the product.

Amino Acid Training Kit

Amino Acid Training Kit (USA)

BGE

BGE (EU)
BGE (UK)
BGE (USA)

Diluent: SMA

Diluent: SMA (EU)
Diluent: SMA (UK)
Diluent: SMA (USA)

IQOQ Standard: SMA

IQOQ Standard: SMA (EU)
IQOQ Standard: SMA (UK)
IQOQ Standard: SMA (USA)

Standard

Standard (EU)
Standard (UK)
Standard (USA)

[post_title] => SDS - REBEL [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => sds-rebel [to_ping] => [pinged] => [post_modified] => 2024-11-15 17:54:50 [post_modified_gmt] => 2024-11-15 22:54:50 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=24599 [menu_order] => 228 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 5906 [post_author] => 29 [post_date] => 2022-04-14 12:53:24 [post_date_gmt] => 2022-04-14 16:53:24 [post_content] =>

Download this Safety Data Sheet (SDS) for documentation related to the properties of each chemical in the product; the physical, health, and environmental health hazards; protective measures; and safety precautions for handling, storing, and transporting the product.

Deoxyribonucleic Acid, Unmodified

SDS Deoxyribonucleic Acid, Unmodified

Interface Tray Grease

SDS Interface Tray Grease

Standard: Amino Acids

SDS Standard: Amino Acids (EU)
SDS Standard: Amino Acids (UK)
SDS Standard: Amino Acids (USA)

Additive: Charge Variant Analysis

SDS Additive: Charge Variant Analysis (EU)
SDS Additive: Charge Variant Analysis (UK)
SDS Additive: Charge Variant Analysis (USA)

BGE: Charge Variant Analysis

BGE: Charge Variant Analysis (EU)
BGE: Charge Variant Analysis (UK)
BGE: Charge Variant Analysis (USA)

Diluent: Charge Variant Analysis

Diluent: Charge Variant Analysis (EU)
Diluent: Charge Variant Analysis (UK)
Diluent: Charge Variant Analysis (USA)

BGE: Intact Antibodies

BGE: Intact Antibodies (EU)
BGE: Intact Antibodies (UK)
BGE: Intact Antibodies (USA)

Diluent: Intact Antibodies

Diluent: Intact Antibodies (EU)
Diluent: Intact Antibodies (UK)
Diluent: Intact Antibodies (USA)

Acid: Metabolites

Acid: Metabolites (EU)
Acid: Metabolites (UK)
Acid: Metabolites (USA)

BGE: Metabolites

BGE: Metabolites (EU)
BGE: Metabolites (UK)
BGE: Metabolites (USA)

Diluent: Metabolites

Diluent: Metabolites (EU)
Diluent: Metabolites (UK)
Diluent: Metabolites (USA)

BGE: Native Antibodies

BGE: Native Antibodies (EU)
BGE: Native Antibodies (UK)
BGE: Native Antibodies (USA)

Diluent: Native Antibodies

Diluent: Native Antibodies (EU)
Diluent: Native Antibodies (UK)
Diluent: Native Antibodies (USA)

BGE: Oligos

BGE: Oligos (EU)
BGE: Oligos (UK)
BGE: Oligos (USA)

Diluent: Oligos

Diluent: Oligos (EU)
Diluent: Oligos (UK)
Diluent: Oligos (USA)

BGE: Peptides

BGE: Peptides (EU)
BGE: Peptides (UK)
BGE: Peptides (USA)

Diluent: Peptides

Diluent: Peptides (EU)
Diluent: Peptides (UK)
Diluent: Peptides (USA)

[post_title] => SDS - ZipChip [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => sds-zipchip [to_ping] => [pinged] => [post_modified] => 2024-11-15 14:46:57 [post_modified_gmt] => 2024-11-15 19:46:57 [post_content_filtered] => [post_parent] => 0 [guid] => https://908devices.com/?post_type=resource&p=5906 [menu_order] => 230 [post_type] => resource [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 3 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 26219 [post_author] => 29 [post_date] => 2024-11-04 15:38:45 [post_date_gmt] => 2024-11-04 20:38:45 [post_content] =>

Download Safety Data Sheet (SDS) for documentation related to the properties of each chemical in the product; the physical, health, and environmental health hazards; protective measures; and safety precautions for handling, storing, and transporting the product.  For products where multiple SDS are available, please check the part number and concentration.

Buffer

SDS Buffer salt mixture Glu Lac for cell culture buffer 850.300.136
SDS Buffer solution Glu Lac cell culture 850.300.135
SDS Transport buffer ready to use Ethanol Methanol 850.300.625
SDS Transport buffer ready to use Glucose Lactate 850.300.125

Calibration Standards—Ethanol

SDS Calibration standard Ethanol 850.302.004 [0.5 g/L]
SDS Calibration standard Ethanol 850.302.001 [2 g/L]
SDS Calibration standard Ethanol 850.302.002 [4 g/L]
SDS Calibration standard Ethanol 850.302.005 [40 g/L]

Calibration Standards—Glucose & Lactate

SDS MAVEN Calibration standard Glu_Lac 850.306.000
SDS Calibration standard Glucose Lactate 850.305.000 [0.5glu 0.25lac]
SDS Calibration standard Glucose Lactate 850.305.001 [1glu 0.5lac]
SDS Calibration standard Glucose Lactate 850.305.002 [2glu 1lac]
SDS Calibration standard Glucose Lactate 850.305.003 [4glu 2lac]
SDS Calibration standard Glucose Lactate 850.305.004 [10glu 5lac]