Resource Hub
Application Notes & Snapshots
Charge variant analysis with ZipChip and maXisII
A ZipChip capillary zone electrophoresis system coupled to Bruker maXis II UHR-QTOF offers an alternative selectivity to separate charge variants prior to MS analysis and affords a more complete intact mass characterization without adding complexity or high salt eluents.
A ZipChip Based CZE-MS Analysis for Quick Assessment of Biotherapeutics
From comprehensive characterization to monitoring product degradation characteristics
Charge Variant Analysis Coupled to a SCIEX TripleTOF® 6600+ System Mass Spectrometer
Rapid Characterization of Intact mAb-based Biotherapeutics
Quick screening of intact antibody and ADC
ZipChip for profiling and characterization of antibody charge heterogeneity
Sciex Flexible Solution for MAM with ZipChip
Sciex Presents Charge Heterogeneity of Monoclonal Antibodies with ZipChip
Snapshot: Charge Variant Analysis
Charge Variant Analysis of Native Antibodies for In-depth Characterization of mAb-based Biotherapeutics
Snapshot: High Throughput Charge Variant Analysis
Brochures & Flyers
ZipChip Consumables Guide
Learn how to take the guesswork out of method development with ZipChip. Breeze through your selection in three quick steps.
ZipChip Platform Brochure
Download our platform brochure to learn how ZipChip® platform prepares and separates a wide range of biological samples, then electrosprays them into your mass spec for analysis.
A comprehensive CE-ESI MS solution for BioPharma applications
Case Studies
REBEL + ZipChip help HJB Overcome Scientific Hurdles and Optimize Processes in Biotherapeutic Development
In their search to accelerate R&D and reduce costs, HJB discovered the power of REBEL and ZipChip.
Analysis to unravel biosimilarity of therapeutic proteins
Highly sensitive charge variant analysis of complex biopharmaceuticals
In-depth analysis of top selling biotherapeutics
Posters
Glycosylation Profiling of mAB Subunits With CZE-MS
This ASMS 2022 poster from Bruker shows ZipChip coupled with high resolution mass spectrometry providing charge-based selectivity which can assist with glycoforms separation.
Characterization of ADCs using ZipChip
Fast and Efficient Biopharmaceutical Characterization
Characterization of charge heterogeneity of mAb
Rapid, Multi-level Analysis of Complex Proteins
Advancing mAb Characterization with Microchip CE-MS Couples to a PASEF Enabled QTOF
Native Analysis of Monoclonal Antibodies
Native CE-MS for Biopharmaceutical Characterization
NIBRT Presents Native MS for Charge Variants using ZipChip
NIBRT Presents ZipChip for Native Charge Heterogeneity
Videos
Webinars
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