Poster Note: Bottom-up analysis of progressively larger RNAs by CZE-MS and CZE-MS/MS
This project explores the merits of CZE as a potential alternative to liquid chromatography, as the front-end separation of choice for analyzing progressively larger RNAs with a bottom-up approach.
Poster Note: Rapid Characterization of Oligos Using Microchip CE-MS without Ion-Pairing Reagents
Learn how ZipChip’s ready-to-use oligos BGE solution is free from ion-pairing reagents and makes switching between applications simple and easy.
Rapid characterization of oligonucleotides using microfluidic CE-MS by ZipChip
This application note presents a CE-MS analysis of oligos by a ZipChip coupled to a QExactive HF mass spectrometer. This positive ESI mode method utilizes a MS-friendly background electrolyte (BGE), that eliminates the use of ion-paring agents such as hexafluoro isopropanol or alkyl amines.
ZipChip Consumables Guide
Learn how to take the guesswork out of method development with ZipChip. Breeze through your selection in three quick steps.
Hassle-Free Oligo Characterization with ZipChip
The newly released ZipChip® oligos kit provides a simple, sensitive, dilute-and-shoot method for rapid analysis of oligonucleotides, applicable to
various sizes and modifications.
Bottom-Up Analysis of Progressively Larger RNAs by CZE-MS and CZE-MS/MS
In this poster from ASMS 2022, researchers from University of Connecticut and Bruker showed that capillary zone electrophoresis performed on a chip proved to be an effective alternative to liquid chromatography as a front-end separation system to analyze both pure samples and complex digestion mixtures of nucleic acids.
CE-MS of Oligonucleotides using a ZipChip
This ASMS 2022 poster from Boehringer Ingelheim explores the use of ZipChip coupled to a high resolution mass spectrometer as an orthogonal method to chromatography for oligonucleotide analysis.
Rapid Characterization of Oligos and Related Impurities Using Microchip CE-MS Without Ion-pairing Reagents
This poster from ASMS 2022 describes a simple & fast method for oligonucleotide characterizations using a Microchip CE-MS platform.
A Microchip CE-MS Based End-to-End Solution for the Analysis of Synthetic Oligonucleotides
This poster showcases a workflow using microchip CE-MS that is coupled with a vendor-neutral informatics platform
as a complete solution for the analysis of synthetic oligos.
Microchip CE-MS of Oligonucleotides: What Can It Separate?
Oligonucleotide Analysis via Microfluidic CE-MS
Interview: The Key to Unsolved Insights into RNA Characterization?
Recorded at ASMS 2022, Dan Fabris from the University of Connecticut shares his experience with RNA characterization using ZipChip.
Interview: Oligonucleotide Analysis with ZipChip at Boehringer Ingelheim
Recorded at ASMS 2022, Vladimir Papov shares his experience with oligo analysis using ZipChip.
Whiteboard Explainer: Avoiding the Stickiness of Oligo Analysis
If you have worked with oligos before, you know this can be a challenging application. Fortunately, ZipChip offers a way to make workflows faster and easier.
ZipChip Poster Chat
Application Experience: Oligonucleotides
Oligo Analysis Simplified: Get Your Answers Faster with Microchip CE-MS
Simplifying Oligonucleotide Characterization with Microchip CE-MS
In this on-demand webinar, we present a microfluidic capillary zone electrophoresis-based separation coupled with HRAM mass-spectrometry for rapid characterization of oligos in positive ionisation mode.
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