Poster Note: Multi-Level Expeditious Characterization of AAV Capsid Proteins using ZipChip
This poster note presents a novel approach to complete characterization of capsid viral proteins using microchip CE-MS for the characterization of AAVs.
Glucose and Lactate Raman-Based Monitoring with MAVERICK: Performance in Spent Media
MAVERICK provides a plug-and-play, in-line, Raman based PAT solution for monitoring and control of glucose, lactate, and biomass in up to 6 bioreactors. This Application Snapshot shows the results from experiments to demonstrate the selectivity of glucose and lactate measurements from MAVERICK in complex spent media samples from CHO and HEK293 cultures.
RPMI 1640 Medium Analysis with the REBEL: Accuracy and Reproducibility Across Multiple Devices
This extensive fresh media analysis experiment provides an example of the accuracy and reproducibility of the REBEL device obtained with RPMI media.
Application Snapshot Booklet Cell and Gene Therapy
Application Snapshot Booklet Cell Culture
Application Snapshot Booklet
Download our full collection of application snapshots, with focuses on biologics, CGT, and fermentation.
Screening of chemically-defined media for suspension cultures of HEK293 cells
Across four vendors, there was a high variation in the fresh media composition.
Serum supplemented media analysis is routine with the Rebel
Supplementing RPMI media with fetal bovine serum
Supplementing IMDM media with fetal bovine serum
Amino acid contents of Sf9 and Sf21 insect cell media
Knowledge of the insect cell metabolism coupled with an understanding of the amino acid content of the cell media allows for a more informed process development analytics strategy.
Handle non-ionic surfactants in cell media samples with ease
Basal cell media with 10% fetal bovine serum
MAVEN offers monitoring and control of glucose and lactate concentrations during cell culture and fermentation. Download this brochure to learn more.
REBEL Certified User Training
Get the best user experience with the REBEL at-line spent media analyzer. Our training course is for new and experienced users who want to refresh their REBEL device
REBEL Spent Media Analysis Kits
The REBEL Spent Media Analysis (SMA) kit is designed to give you all the consumable components needed to run your samples quickly and move your projects forward faster.
Real-time bioprocess monitoring and control, right out of the box. In-line measurements of multiple critical parameters across media, across processes, across mammalian cell lines, across scales.
The REBEL is a novel, dedicated cell culture media analyzer designed for rapid, easy, and efficient amino acid and nutrient analysis.
MAVEN Specification Sheet
Get all the MAVEN specifications, including measurement range, physical dimensions, and software requirements.
MAVERICK Product Specification Sheet
Get all the MAVERICK specifications including applications, physical dimensions, and more.
REBEL Specifications Sheet
Get quantitative identification and analysis on a panel of >30 analytes including key amino acids, biogenic amines, and water soluble vitamins.
Instant Implementation of Raman-based PAT with MAVERICK for Monitoring Glucose and Lactate
MAVERICK is easy to set up and enables instant implementation of PAT generating accurate, precise, linear and selective in-line measurements across a wide range of media used typically in mammalian (including CHO and HEK293 media) cell culture for the production of biotherapeutics.
Determining Total Cell Count with MAVERICK Biomass Measurements
MAVERICK provides an in-line, Raman-based PAT solution for monitoring and control of glucose, lactate, and biomass in up to six bioreactors right out of the box.
On-line Measurement of Glucose and Lactate with Automated Feedback Control
MAVEN answers the urgent need for on-line measurements and automated control of glucose levels, which reduces manual labor, lowers risk of contamination from sampling, decreases risk of human error with feeding, and reduces the stress that cells may experience from variable glucose levels.
MAVERICK: Raman-based Monitoring of Multiple Critical Parameters, Ready to Go in Minutes
MAVERICK is powered by Raman spectroscopy and purpose-built de novo model for simultaneous real-time measurements of multiple key process parameters in mammalian cell cultures without the costs, complexities, and risks of conventional methods.
MAVERICK: Monitoring of Multiple Bioprocess Parameters Right out of the Box
There’s no need to deal with complex empirical calibration models, reagents, or unreliable auto-sampling systems to implement in-line bioreactor monitoring.
MAVEN Product Video
If glucose and lactate measurements run your lab’s schedule, it’s time to meet MAVEN.
REBEL Product Video
Engineering Functionally Improved CAR T cells with a Multi-Cytokine Backpack Platform with Insights into Metabolism
In-line Monitoring of Bioprocess Analysis Parameters for the 21st Century
Now Starts Now: The Future of Glucose & Lactate Measurement
Learn how MAVEN addresses the challenges of on-line nutrient and metabolite monitoring and control.
Benefits of Real-time Analytics to Overcome Common Cell Culture Challenges
MAVEN gives you optimized, automated, don’t-even-sweat-it control of glucose and lactate concentrations in cell culture and fermentation.
Reduce Media Development Timelines
Does cell culture analysis matter for CGT development? This short webinar explores what is already known, reviews at-line methods for cell culture media analysis, and shares recent data from two case studies.
Unlocking rapid cell culture media analysis for cell and gene therapy process development
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