Resource Hub
Application Notes & Snapshots
Application Report: Glucose Control
The online analyser TRACE C2 Control allows a rapid and precise determination of glucose and lactate concentrations inside the bioreactor.
Application Report: Ethanol Dialysis
The online analyzer TRACE C2 Control allows a rapid and precise determination of the Ethanol concentration in the fermenter.
Application Report: Methanol Dialysis
The online analyzer TRACE C2 Control allows a rapid and precise determination of the methanol concentration in the fermenter and provides the tools for a quick set-up of a feed control strategy
Application Report: Glucose & Lactate (in Small Bioreactors)
The online analyser TRACE C2 Control allows a rapid and precise determination of glucose and lactate concentrations inside small bioreactors.
Application Report: Glucose & Lactate
The online analyzer TRACE C2 Control allows a rapid and precise determination of glucose and lactate concentrations inside the bioreactor.
Posters
Process Optimization by the Use of Substrate Feeding Strategies
Online glucose monitoring is possible by using Trace C2 Control system. Feed control without online glucose monitoring causes acetate formation due to overflow metabolism.
Optimized Fed-Batch Fermentation by Use of Online Glucose Measurement
This poster presentation features an integrated multivariate glucose measuring tool combined with software solutions which allow different types of feeding-strategies.
High Frequency Glucose and Lactate Measurements in Multi-Bioreactor Vessels
TRACE C2 is an online analyzer for monitoring and controlling glucose and lactate concentrations in bioreactors. With the extension M4 it is possible to monitor Glucose and Lactate in up to four simultaneous bioprocesses.
Online-Controlling of Glucose in Cultivations and Fermentations
TRACE C2 Control is a new online analyzer for monitoring and controlling of glucose concentrations in bioprocesses. In disturbance reaction experiments and in an E.coli fermentation it can be successfully shown that a reliable control is possible.
Implementation of a New Method for Online Glucose Control in a 10L CHO Bioprocess
This poster shows how glucose concentration can be directly measured based on an enzymatic reaction. This method is then used to control the glucose level in a fed-batch fermentation at a
constant level.
Single-Use Bioreactor for High Density Bacterial Fermentation
Glucose measurement is performed on-line using the TRACE C2 analyser. This allows to follow-up glucose uptake rate and monitor fed batch culture with retro-control on the glucose pump such as maintain glucose level at predefined set point.
Specification Sheets
Technical Papers
Tech Note: Glucose & Lactate Dialysis (Low)
These data were compiled in order to give an overview of typical system and sensor performance in the low concentration range using the dialysis-low sampling method. Operational temperature in the bioreactor was set to 37°C.
Tech Note: Glucose & Lactate Dialysis
These data were compiled in order to give an overview of the system and sensor performance in the normal concentration range using the dialysis sampling method.
Tech Note: Pressure Stability of the Dialysis Probe
The TRACE dialysis probe can be safely used in large reactors. Its dialysis membrane does not suffer from higher pressure due to hydrostatic and/ or pressurized conditions.
Tech Note: Interference of Other Sugars on Glucose and Lactate Measurements
Most sugars have no influence on glucose measurement. The only exception is mannose, which shows a low positive interference on the glucose measurement.
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