Cell Culture Media Analysis
Nutrient profiling at-line, anytime
Cell Culture Media Matters. Here’s Why.
Cell culture media analysis is a critical piece of the bioprocessing puzzle. From starting material and throughout the growth cycle, cell culture media analysis gives you a clearer, fuller picture of how amino acids, vitamins and biogenic amines impact cell health and productivity.
Media QC
Analyzing fresh media to assess variability between lots or different formulations means you’ve got it right from the get-go.
Media Selection & Optimization
Selecting the right medium and refining nutrient levels boosts production. The REBEL cell culture analyzer can help you choose which way to go.
Spent Media Analysis
Tracking metabolites in near real time allows proactive feeding strategies to replenish or fortify when nutrients are critically low in concentration.
Process Monitoring
During late stage PD or scale-up, the REBEL integrated in a PAT workflow can monitor nutrient levels critical to process stability and product quality.
What’s In Your Bioreactor?
Optimize Cell Culture Media in Real Time
The REBEL
Time for a new routine. One that lets you call shots faster. Analyze anything from raw material QC to spent media and get quantitative reports for amino acids, dipeptides, water soluble vitamins and biogenic amines in any cell media, any time.
REBEL Resources:
Suggested Resources
Rapid Analysis of Cell Therapy Media
Rapid at-line amino acid and nutrient profiling from bioprocess media with the REBEL
Screening of chemically-defined media for suspension cultures of HEK293 cells
Across four vendors, there was a high variation in the fresh media composition.
Amino acid contents of Sf9 and Sf21 insect cell media
Knowledge of the insect cell metabolism coupled with an understanding of the amino acid content of the cell media allows for a more informed process development analytics strategy.
Spent Media Analysis of CHO Grown in an Ammonia-Stressed Parallel Microbioreactor Platform
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