The Importance of Cell Media Analysis in Cell Therapy Development
One of the keys to cell therapy process development lies in the cell culture media used to culture the cells after isolation.
Read the other articles in this series: Metabolomics Analysis in Cell Therapy Development, Analyzing Serum-Free Media for Cell Therapy Applications, Spent Media Analysis to Improve Cell Therapy Manufacturing
In the field of regenerative medicine, cell and gene therapies are increasingly becoming viable therapeutic alternatives to traditional treatments for a wide range of diseases.
Most recently, T-cells have been the focus of much clinical investment with chimeric antigen receptor (CAR) T-cell immunotherapies for blood cancers, but other cell types including mesenchymal stem cells (MSCs) and other immune cells (i.e., NK cells, macrophages) have also been investigated for their therapeutic potential. Regardless of the cell type, understanding the best way to culture the cells in vitro to achieve optimal cell activation and expansion, while maintaining functionality is key to the success of these “living medicines”.
There is a wide range of cell culture media available from do-it-yourself recipes to commercially available one-size-fits-all complete formulations. It can be a challenging landscape to navigate when identifying the optimal culture media for your cell type because of the diversity of compositions and a multitude of options for each cell type.
The Critical Role of Cell Culture Media Analysis in CGT Development
Does cell culture analysis matter for CGT development? This short webinar explores what is already known, reviews at-line methods for cell culture media analysis, and shares recent data from two case studies.
Keep Reading About CGT Process Development
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What’s In Your Media?
Take a deep dive into the role that cell culture media analysis plays across bioproduction, cell therapies, and gene therapies.
Solution for Cell Therapy Process Development
At-line cell culture media analysis. Results on 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.
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