Cell Culture Media Analyzer
REBEL
At-line cell culture media analysis. Results on 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.
Get out of line. Waiting weeks for cell culture media analysis is optional. Get at-line media analysis for 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.
Reduce Downtime Between Experiments & Save Money
Cost Savings: Less bioreactor runs, Less FTE time, Shorter development time.
Traditional Workflow With Core or External Lab Analytics:
REBEL Assisted Workflow:
*REBEL used in combination with modeling can lead to fewer bioreactor runs.
Trusted by BioPharma
Listen to how scientists have put REBEL to use in speeding up their research.
What If You Could Reduce Analytics from 3-6 Weeks to 10 Minutes?
Conventional Analytics: 3 to 6 Weeks
The traditional analytics process can take 3–6 weeks, which can lead to prolonged decision-making.
STEP ONE
Pull sample
STEP TWO
Filter cells
STEP THREE
Label, secure, collect, freeze samples (14 days), and fill out paperwork
STEP FOUR
Send frozen batch to core lab
STEP FIVE
Core lab defrosts, dilutes, preps derivatization reagents
STEP SIX
Core lab mixes samples with chemicals
STEP SEVEN
Reacted samples put into HPLC
STEP EIGHT
Run HPLC, acquire data
STEP NINE
Analyze data, summarize results
Report Generated
REBEL Analytics: 10 Minutes
The REBEL provides analytics within 10 minutes, enabling quick decision-making.
STEP ONE
Pull sample
STEP TWO
Spin out cells and dilute
STEP THREE
Insert sample into REBEL
STEP FOUR
Start REBEL
Report Generated!
Take Charge
Getting results is drama-free. Pull a bioreactor sample, spin it down, and dilute. Load into the REBEL and hit start. Run samples solo or in 96-well plates if you’re on a roll. There’s no messing around with settings or data analysis either. Reports kick out automatically and upload to your network drive.
Download Sample Report:
Remove Data Analysis Bottlenecks
REBEL users with access to the JMP statistical software package are able to expedite high-throughput data analysis by REBEL data visualization. REBEL users can download the add-in tool from the 908 Devices customer support portal. To learn more about the REBEL and the visualization tool, watch the BPI: Ask the Expert Webinar, and click the button to obtain a JMP software trial.
REBEL Data Processing
Quantitative numbers for each analyte, from each sample directly from the REBEL.
JMP Statistical Discovery
Expedite high-throughput data analysis from REBEL with JMP statistical discovery software.
Consumables That Don’t Consume Your Time
Easy Sample
Preparation
Just filter, spin, and dilute your samples. There’s no chemical reaction, and it works for both low and high sample throughput needs
Low-Effort Method Development
Use the touch screen to get the sample running. BGE carries the samples through the microchip for ESI-MS detection
Simple System
Check
The REBEL makes it easy with a built-in quantification calibration and system performance check with REBEL SMA standard
Comprehensive
Analysis
30+ analytes including amino acids, vitamins, and amines are quantified in as little as 10 minutes per sample
How Will You Use REBEL?
Monitor amino acids and vitamins throughout your bioreactor time course. Refine feeding strategies on the fly. Correlate media selection to product quality and yield.
What’s On The Menu:
Amino Acids
- Alanine
- Alanyl-Glutamine
- Arginine
- Asparagine
- Aspartic acid
- Betaine
- Cystine
- Glutamic acid
- Glutamine
- Glycine
- Histidine
- Isoleucine
- Leucine
- Lysine
- Methionine
- Phenylalanine
- Proline
- Serine
- Threonine
- Tryptophan
- Tyrosine
- Valine
Biogenic Amines
- GABA
- Beta-Alanine
- Hydroxyproline
- Methyl-L-histidine
- L-Citrulline
Vitamins
- Choline
- Nicotinamide
- Pyridoxal
- Pyridoxine
- Thiamine
Featured Resources
REBEL Brochure
The REBEL is a novel, dedicated cell culture media analyzer designed for rapid, easy, and efficient amino acid and nutrient analysis.
REBEL Specifications Sheet
Get quantitative identification and analysis on a panel of >30 analytes including key amino acids, biogenic amines, and water soluble vitamins.
REBEL Product Video
Be a REBEL with Your Cell Media Analytics
Customer Support Portal
The My 908 portal gives scientists quick access to important resources like the latest software upgrades, product guides, and training materials.
Frequently Asked Questions
How do I load samples and queue up a run on the REBEL?
The REBEL accepts both septa capped vials and 96-well plates. We provide two plates with each consumable kit. The REBEL’s autosampler is cooled to 5 °C, and there are plate covers included in the kits to prevent evaporation. Once your samples are loaded, you can manually input your sample information using the REBEL’s intuitive user interface and touchscreen or import a CSV template file that you have already prefilled. The template expedites the process if you are loading a full plate of samples, and we provide the template to you during installation.
What data formats does the REBEL export, and how are the files saved?
The REBEL saves processed reports in either CSV or PDF file formats. When configured for network storage, the files are saved in real time. No permanent storage of data files or reports is ensured on the REBEL if saved on the internal storage system. It is expected that your company’s corporate IT policies can be employed for the resulting files deposited on network shares for long term retention, fraud prevention and adulteration.
How does the REBEL fit alongside my current workflows?
In a typical process development or cell culture lab, the REBEL fits along with all your other process analytics like a cell viability and general biochemical analyzers. By implementing the REBEL in the same lab as your other gear, you can eliminate the need to send out your samples to a core lab, saving a significant amount of time. Gaining near-real time analytics on an extended list of analytes and nutrients in your bioreactors and fermenters allows you to improve your efficiency in the lab instead of waiting weeks for your data.
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