Cell Culture Media Analyzer

The REBEL


At-line cell culture media analysis. Results on 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.

Simple:
Easy to understand answers
Actionable:
No more waiting for third party testing
Reproducible:
Accurate, reliable performance whether running 1 or 100 samples

Get out of line. Waiting weeks for cell culture media analysis is optional. Get at-line media analysis for 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.

Reduce Downtime Between Experiments & Save Money

Cost Savings: Less bioreactor runs,  Less FTE time, Shorter development time.

Traditional Workflow With Core or External Lab Analytics:
vs

REBEL Assisted Workflow:

*REBEL used in combination with modeling can lead to fewer bioreactor runs.

Trusted by BioPharma

Listen to how scientists have put REBEL to use in speeding up their research.

What If You Could Reduce Analytics from 3-6 Weeks to 10 Minutes?

The traditional analytics process can take 3–6 weeks, which can lead to prolonged decision-making.

Pull sample

Filter cells

Label, secure, collect, freeze samples (14 days), and fill out paperwork

Send frozen batch to core lab

Core lab defrosts, dilutes, preps derivatization reagents

Core lab mixes samples with chemicals

Reacted samples put into HPLC

Run HPLC, acquire data

Analyze data, summarize results


The REBEL provides analytics within 10 minutes, enabling quick decision-making.

Pull sample

Spin out cells and dilute

Insert sample into REBEL

Start REBEL

Take Charge

Getting results is drama-free. Pull a bioreactor sample, spin it down, and dilute. Load into the REBEL and hit start. Run samples solo or in 96-well plates if you’re on a roll. There’s no messing around with settings or data analysis either. Reports kick out automatically and upload to your network drive.


Download Sample Report:

Remove Data Analysis Bottlenecks

REBEL users with access to the JMP statistical software package are able to expedite high-throughput data analysis by REBEL data visualization. REBEL users can download the add-in tool from the 908 Devices customer support portal. To learn more about the REBEL and the visualization tool, watch the BPI: Ask the Expert Webinar, and click the button to obtain a JMP software trial.

Quantitative numbers for each analyte, from each sample directly from the REBEL.

Expedite high-throughput data analysis from REBEL with JMP statistical discovery software.

Consumables That Don’t Consume Your Time

Easy Sample
Preparation

Just filter, spin, and dilute your samples. There’s no chemical reaction, and it works for both low and high sample throughput needs

Low-Effort Method Development

Use the touch screen to get the sample running. BGE carries the samples through the microchip for ESI-MS detection

Simple System
Check

The REBEL makes it easy with a built-in quantification calibration and system performance check with REBEL SMA standard

Comprehensive
Analysis

30+ analytes including amino acids, vitamins, and amines are quantified in as little as 10 minutes per sample

How Will You Use REBEL?

Monitor amino acids and vitamins throughout your bioreactor time course. Refine feeding strategies on the fly. Correlate media selection to product quality and yield.

What’s On The Menu:

Amino Acids

  • Alanine
  • Alanyl-Glutamine
  • Arginine
  • Asparagine
  • Aspartic acid
  • Betaine
  • Cystine
  • Glutamic acid
  • Glutamine
  • Glycine
  • Histidine
  • Isoleucine
  • Leucine
  • Lysine
  • Methionine
  • Phenylalanine
  • Proline
  • Serine
  • Threonine
  • Tryptophan
  • Tyrosine
  • Valine

Biogenic Amines

  • GABA
  • Beta-Alanine
  • Hydroxyproline
  • Methyl-L-histidine
  • L-Citrulline

Vitamins

  • Choline
  • Nicotinamide
  • Pyridoxal
  • Pyridoxine
  • Thiamine

Customer Support Portal

The My 908 portal gives scientists quick access to important resources like the latest software upgrades, product guides, and training materials.

Frequently Asked Questions

How do I load samples and queue up a run on the REBEL?

The REBEL accepts both septa capped vials and 96-well plates. We provide two plates with each consumable kit. The REBEL’s autosampler is cooled to 5 °C, and there are plate covers included in the kits to prevent evaporation. Once your samples are loaded, you can manually input your sample information using the REBEL’s intuitive user interface and touchscreen or import a CSV template file that you have already prefilled. The template expedites the process if you are loading a full plate of samples, and we provide the template to you during installation.

What data formats does the REBEL export, and how are the files saved?

The REBEL saves processed reports in either CSV or PDF file formats. When configured for network storage, the files are saved in real time. No permanent storage of data files or reports is ensured on the REBEL if saved on the internal storage system. It is expected that your company’s corporate IT policies can be employed for the resulting files deposited on network shares for long term retention, fraud prevention and adulteration.

How does the REBEL fit alongside my current workflows?

In a typical process development or cell culture lab, the REBEL fits along with all your other process analytics like a cell viability and general biochemical analyzers. By implementing the REBEL in the same lab as your other gear, you can eliminate the need to send out your samples to a core lab, saving a significant amount of time. Gaining near-real time analytics on an extended list of analytes and nutrients in your bioreactors and fermenters allows you to improve your efficiency in the lab instead of waiting weeks for your data.

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