Bottom-Up Analysis of Progressively Larger RNAs by CZE-MS and CZE-MS/MS
In this poster from ASMS 2022, researchers from University of Connecticut and Bruker showed that capillary zone electrophoresis performed on a chip proved to be an effective alternative to liquid chromatography as a front-end separation system to analyze both pure samples and complex digestion mixtures of nucleic acids.
Multi-level Expeditious Characterization of Adeno-associated Virus (AAV) Capsid Proteins Using ZipChip Microfluidic CE Coupled with HRMS
In this poster from ASMS 2022, scientists from Thermo Fisher Scientific and 908 Devices present a novel approach using microchip CE-MS for the characterization of AAVs.
A Sensitive and High-Throughput Assay for Analyzing Peptide Exchanged MHCl by High-Resolution Native CZE-MS
In this poster from ASMS 2022, researchers from Genentech describe a sensitive and high-throughput assay using capillary-zone electrophoresis coupled to a high-resolution mass spectrometer for characterizing peptide-exchanged MHCI under native conditions.
Combining μSPE ZipChip CE with PRM-LIVE on a timsTOF Pro for Warp-speed Selectivity Profiling of Deubiquitinase (DUB) Small Molecule Inhibitors
In this ASMS 2022 poster, researchers from Dana Farber Cancer Institute and Harvard Medical School developed a ZipChip-based method for facilitating high-throughput identification
of new small molecule inhibitors.
Microchip CE-MS Analysis of Sialylated N-glycan Linkage Isomers
In this ASMS 2022 poster, Fudan University researchers show a ZipChip-based strategy for qualitative and quantitative analysis of sialylated N-glycan linkage isomers was developed.
CE-MS of Oligonucleotides using a ZipChip
This ASMS 2022 poster from Boehringer Ingelheim explores the use of ZipChip coupled to a high resolution mass spectrometer as an orthogonal method to chromatography for oligonucleotide analysis.
Glycosylation Profiling of mAB Subunits With CZE-MS
This ASMS 2022 poster from Bruker shows ZipChip coupled with high resolution mass spectrometry providing charge-based selectivity which can assist with glycoforms separation.
Rapid Characterization of Oligos and Related Impurities Using Microchip CE-MS Without Ion-pairing Reagents
This poster from ASMS 2022 describes a simple & fast method for oligonucleotide characterizations using a Microchip CE-MS platform.
Using CE-HPMS For Accelerated Process Development of a mAb-Expressing Cell Line
The coupling of miniature mass spectrometry (MS) to a microchip capillary electrophoresis (CE) platform provides a simple solution for at-line amino acid quantitation.
Pushing the Boundaries of Speed and Sensitivity in Proteomics
To overcome sample loading limitations in CE-MS, the poster authors engineered a 1 mm SPE bed within the chip geometry, allowing 100-fold improvements in concentration sensitivity limit for CE-MS.
A Broad Application of Migration Time Indexing and Metabolite Libraries to Evaluate Quantitative Coverage in Microchip CE-MS Metabolomics
In the field of metabolomics, microchip capillary electrophoresis (mCE) has a number of potential advantages over traditional liquid chromatography (LC), including higher throughput due to decreased separation times, increased separation efficiency, and lower required sample volumes.
Dynamic Range Optimization for Amino Acid Quantitation with an Integrated CE-MS Analyzer
The coupling of miniature mass spectrometry (MS) to a microchip capillary electrophoresis (CE) platform provides a simple solution for amino acid quantitation.
A Microchip CE-MS Based End-to-End Solution for the Analysis of Synthetic Oligonucleotides
This poster showcases a workflow using microchip CE-MS that is coupled with a vendor-neutral informatics platform
as a complete solution for the analysis of synthetic oligos.
Rapid at line quantitation of key nutrients in cell culture media
This poster details the benefits of coupling of miniature mass spectrometry to a microchip capillary electrophoresis platform for characterizing cell media metabolites in fresh and spent media.
Microchip CE-MS with Integrated Solid Phase Extraction
Quantitation of metabolites in classical and customized cell culture media by an integrated CE-MS Analyzer
Quantitation of metabolites in cell culture media by an integrated CE-MS analyzer for upstream process development
Microchip CE-MS of Oligonucleotides: What Can It Separate?
Fast Chip-CEMS for Characterization of Protein/PTM Changes
Characterization of ADCs using ZipChip
Combined Top-down and Bottom-up Proteomics
ZipChip for Glycomics and Glycoproteomics
Fast and Efficient Biopharmaceutical Characterization
Characterization of charge heterogeneity of mAb
Rapid, Multi-level Analysis of Complex Proteins
Oligonucleotide Analysis via Microfluidic CE-MS
Advancing mAb Characterization with Microchip CE-MS Couples to a PASEF Enabled QTOF
96 Bottles of Beer: Metabolic Profiling of Spent Growth Media
Using genomic and spent media analysis to characterize stressed CHO cultures
Native Analysis of Monoclonal Antibodies
Characterization of Protein/PTM Changes
Native CE-MS for Biopharmaceutical Characterization
A Rapid Microfluidic Method for Molecular Weight Determination and Spent Media Analysis of an IgG1 Intact Protein in Growth Media
Characterizing the Analytical Performance and Reliability of Metabolite Quantitation by an Integrated CE-MS Analyzer
Rapid Analysis of Cell Therapy Media
Quantitation of CHO media nutrients and metabolites in under 180 seconds
Rapid analysis of amino acids, water soluble vitamins, biogenic amines and dipeptides in cell growth media
Rapid at line nutrient profiling from an ammonia stressed CHO cell line
Bioprocessing of Monoclonal Antibody Based Therapies
NIBRT Presents Native MS for Charge Variants using ZipChip
NIBRT Presents ZipChip for Native Charge Heterogeneity
Monitoring Amino Acid Composition of Cell Culture Media
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