In-Process Analytics are Key to Successful Cell Therapy Process Optimization and Manufacturing
Cellular therapies are an increasingly viable therapeutic option for many indications, particularly for patients who have exhausted traditional treatments. Considerable clinical activity and the approval of several autologous, patient-specific therapies has increased industry demand and has also highlighted bottlenecks in manufacturing workflows.
The Critical Role of CE-MS Methods for Biotherapeutic Characterization
Capillary electrophoresis (CE) methods play an important role in biomolecular characterization while microfluidic CE-mass spectrometry (MS) accelerates analytical workflows and improves development/commercialization timelines.
Identification of AAV capsid proteins
Characterization of a SRPK1/2 Inhibitor Complex
Detection and Quantification of neurotoxin β-N-methylamino-l-alanine
Characterizing Covalent CDK Inhibitor Complexes
MX908_Article_Trace Detection Tools for Synthetic Opioids
Rapid Fingerprinting of a Highly Glycosylated Fusion Protein
Analysis of monosaccharides, oligosaccharides and glycopeptides
Metabolite Profiling Reveals Predictive Biomarkers
Monitoring Glycosylation Profile and Protein Titer in Cell Culture Samples
Characterizing Antiviral Protein-Inhibitor Complexes
Characterization of NIST mAb Proteoforms and Glycoforms
Spent Media Analysis of CHO Grown in an Ammonia-Stressed Parallel Microbioreactor Platform
In-depth analysis of monoclonal antibodies using microfluidic capillary electrophoresis and native mass spectrometry
Comparative Elucidation of Cetuximab Heterogeneity on the Intact Protein Level
Characterization of Protein Assemblies Related to Cancer Proliferation
Analysis of alkaloids in plant cell cultures
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