Published Article

In-Process Analytics are Key to Successful Cell Therapy Process Optimization and Manufacturing

Cellular therapies are an increasingly viable therapeutic option for many indications, particularly for patients who have exhausted traditional treatments. Considerable clinical activity and the approval of several autologous, patient-specific therapies has increased industry demand and has also highlighted bottlenecks in manufacturing workflows.

The Critical Role of CE-MS Methods for Biotherapeutic Characterization

Capillary electrophoresis (CE) methods play an important role in biomolecular characterization while microfluidic CE-mass spectrometry (MS) accelerates analytical workflows and improves development/commercialization timelines.

Identification of AAV capsid proteins

Characterization of a SRPK1/2 Inhibitor Complex

Detection and Quantification of neurotoxin β-N-methylamino-l-alanine

Characterizing Covalent CDK Inhibitor Complexes

Trace Detection Tools for Synthetic Opioids

MX908_Article_Trace Detection Tools for Synthetic Opioids

Rapid Fingerprinting of a Highly Glycosylated Fusion Protein

Analysis of monosaccharides, oligosaccharides and glycopeptides

Metabolite Profiling Reveals Predictive Biomarkers

Monitoring Glycosylation Profile and Protein Titer in Cell Culture Samples

Characterizing Antiviral Protein-Inhibitor Complexes

Characterization of NIST mAb Proteoforms and Glycoforms

Spent Media Analysis of CHO Grown in an Ammonia-Stressed Parallel Microbioreactor Platform

In-depth analysis of monoclonal antibodies using microfluidic capillary electrophoresis and native mass spectrometry

Comparative Elucidation of Cetuximab Heterogeneity on the Intact Protein Level

Characterization of Protein Assemblies Related to Cancer Proliferation

Analysis of alkaloids in plant cell cultures

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