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Accelerate Upstream Process Development with Data-driven Feeding Strategy Optimization

At-line and on-line technologies that inform bioprocess parameters and cell-feeding strategies are needed to develop processes that deliver high-quality products while reducing manufacturing costs. In this webinar, Chris Schultz, PhD from CPI provides insights on using at-line spent media analysis and on-line glucose and lactate monitoring for the optimization of feeding strategy.

In today’s bioprocessing industry, speeding up timelines and cutting costs are essential goals. However, it is crucial to maintain product quality when making changes to processes. Utilizing at-line and on-line technologies to monitor bioprocess parameters and cell-feeding strategies is necessary for creating efficient processes that produce top-notch products while also lowering production expenses.

The Centre for Process Innovation (CPI) collaborates with partners in various industries in the UK and globally to advance innovative technologies and help reduce the risks and costs of product development. Dr. Chris Schultz, at CPI, led a project in partnership with 908 Devices to enhance a CHO bioprocess. The main objective was to improve monoclonal antibody production and CHO cell health by making informed decisions when selecting and using suitable cell culture media and feeds. In this webinar, Schultz shares insights on utilizing at-line spent media analysis and online monitoring of glucose and lactate levels to optimize feeding strategies.

  • Accelerate process development by data-driven decision making.
  • Reduce manufacturing costs while improving process efficiency.
  • Use at-line and on-line technology to characterize bioprocesses and improve product yield.

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