Poster Note: Bottom-up analysis of progressively larger RNAs by CZE-MS and CZE-MS/MS

This project explores the merits of CZE as a potential alternative to liquid chromatography, as the front-end separation of choice for analyzing progressively larger RNAs with a bottom-up approach.

Poster Note: Multi-Level Expeditious Characterization of AAV Capsid Proteins using ZipChip

This poster note presents a novel approach to complete characterization of capsid viral proteins using microchip CE-MS for the characterization of AAVs.

Poster Note: Rapid Characterization of Oligos Using Microchip CE-MS without Ion-Pairing Reagents

Learn how ZipChip’s ready-to-use oligos BGE solution is free from ion-pairing reagents and makes switching between applications simple and easy.

Protected: Intact Mass Analysis

Protected: Charge Variant Analysis

A Versatile Platform for Small Molecules, Intact Proteins & Beyond

ZipChip can be used for applications ranging from proteins and peptides in biopharmaceuticals, to oligonucleotides and AAVs in cell and gene therapy applications.

REBEL + ZipChip help HJB Overcome Scientific Hurdles and Optimize Processes in Biotherapeutic Development

In their search to accelerate R&D and reduce costs, HJB discovered the power of REBEL and ZipChip.

Bottom-Up Analysis of Progressively Larger RNAs by CZE-MS and CZE-MS/MS

In this poster from ASMS 2022, researchers from University of Connecticut and Bruker showed that capillary zone electrophoresis performed on a chip proved to be an effective alternative to liquid chromatography as a front-end separation system to analyze both pure samples and complex digestion mixtures of nucleic acids.

Multi-level Expeditious Characterization of Adeno-associated Virus (AAV) Capsid Proteins Using ZipChip Microfluidic CE Coupled with HRMS

In this poster from ASMS 2022, scientists from Thermo Fisher Scientific and 908 Devices present a novel approach using microchip CE-MS for the characterization of AAVs.

A Sensitive and High-Throughput Assay for Analyzing Peptide Exchanged MHCl by High-Resolution Native CZE-MS

In this poster from ASMS 2022, researchers from Genentech describe a sensitive and high-throughput assay using capillary-zone electrophoresis coupled to a high-resolution mass spectrometer for characterizing peptide-exchanged MHCI under native conditions.

Combining μSPE ZipChip CE with PRM-LIVE on a timsTOF Pro for Warp-speed Selectivity Profiling of Deubiquitinase (DUB) Small Molecule Inhibitors

In this ASMS 2022 poster, researchers from Dana Farber Cancer Institute and Harvard Medical School developed a ZipChip-based method for facilitating high-throughput identification
of new small molecule inhibitors.

Microchip CE-MS Analysis of Sialylated N-glycan Linkage Isomers

In this ASMS 2022 poster, Fudan University researchers show a ZipChip-based strategy for qualitative and quantitative analysis of sialylated N-glycan linkage isomers was developed.

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