ZipChip Consumables
ZipChip consumables are preformulated with minimal method development requirements. BGE comes in various pH to match charge state requirements for migration. Chips are the heart of the separation.
Take the Guesswork Out of Method Development
Assay kits come with background electrolyte and sample diluent that’s optimized for each application. Just put the bottle of background electrolyte in the autosampler, prep your samples with the sample diluent and you’re off!
Pick a BGE Kit
Then a Chip
BGE Kits
Background electrolyte (BGE) and sample diluent reduce preparation time for your samples. With ZipChip you just dilute and shoot!
Charge Variant Analysis Kit
Superior performance for native charge variant separations of intact antibodies interfaced with all mass spectrometers.
- Pre-packaged background electrolyte
- Sample diluent
- 625 sample capacity
- For use with HRN or HSN chips only
Related Application Note:
Charge variant analysis with ZipChip and maXisII
Native Antibody Assay Kit
Superior performance for native charge variant separations of intact antibodies interfaced with Orbitrap mass spectrometers.
- Pre-packaged background electrolyte
- Sample diluent
- 625 sample capacity
- For use with HRN or HSN chips only
Related Application Note:
Charge Variant Analysis of Native Antibodies for In-depth Characterization of mAb-based Biotherapeutics
Intact Antibodies Assay Kit
For charge variant separations of intact antibodies using gentle, low pH conditions.
- Pre-packaged background electrolyte
- Sample diluent
- 625 sample capacity
Related Application Note:
Rapid Characterization of Intact mAb-based Biotherapeutics
Peptide Assay Kit
Designed for peptide analysis and peptide mapping. Additional uses may include intact mass analysis of proteins, subunit/reduced mAb analysis, and separations of small proteins.
- Pre-packaged background electrolyte
- Sample diluent
- 625 sample capacity
Related Application Note:
High-Throughput Intact Mass Analysis of mAb Based Therapeutics
Metabolites Assay Kit
Optimized for small molecule analysis. Additional uses may include intact mass analysis of proteins, peptide mapping, and subunit/reduced mAb analysis.
- Pre-packaged background electrolyte
- Sample diluent
- 625 sample capacity
Related Application Note:
Analysis of Reduced mAbs and ADCs
Oligonucleotides Kit
For high resolution accurate mass identification and quantitation of oligonucleotides.
- Pre-packaged background electrolyte
- Sample diluent
- 625 sample capacity
- For use with HSB or HRB chips only
Related Application Note:
Rapid characterization of oligonucleotides using microfluidic CE-MS by ZipChip
It’s All in the Chip
The heart of the technology is the chip itself, which contains the actual glass microchip. The injection cross etched into the chip performs rapid injections of the sample directly into to the separation channel, which terminates at the fully integrated electrospray ionization emitter. It all works together to offer the speed and efficiency inherent to capillary zone electrophoresis separations.
The Chips
Choose from a range of chip options to optimize your workflow. Each chip can be used up to 125 injections.
High Speed Chip enables faster microfluidic separations for faster results. Matching BGE kits: Intact Antibody, Peptides, or Metabolites.
High Speed Native Chip enables fast microfluidic separations for native protein analysis. Matching BGE kits: Native Antibodies or Charge Variant Analysis.
High Speed Bare Glass Chip for high throughput separations. For example: fast oligonucleotides analysis. Matching BGE kit example: Oligos BGE.
High Resolution Chip for applications demanding maximum separation capacities. Matching BGE kits: Intact Antibody, Peptides, or Metabolites.
High Resolution Native Chip with ultimate separation for native protein analysis. Matching BGE kits: Native Antibodies, or Charge Variant Analysis.
High Resolution Bare Glass Chip for high resolution separation of negatively charged analytes such as oligonucleotides. Matching BGE kit example: Oligos BGE.
Ordering Information
Once you have determined a kit and chip, request a quote and we will guide you through from purchase to delivery.
| Assay Kits* | Part Number | Samples Per Kit |
|---|---|---|
| ZipChip Native Antibody Assay Kit | 850-00048 | 625 |
| ZipChip Intact Antibodies Assay Kit | 850-00032 | 625 |
| ZipChip Charge Variant Analysis Kit | 850-00052 | 625 |
| ZipChip Metabolites Assay Kit | 850-00033 | 625 |
| ZipChip Peptide Assay Kit | 850-00034 | 625 |
| ZipChip Oligos Assay Kit | 850-00066 | 625 |
| ZipChip Oligos Starter Kit | 850-00067 | 250 Tests |
| Chips | Part Number | Chips Per Box | Injections Per Chip |
|---|---|---|---|
| HS | 810-00195 | 5 | 125 |
| HR | 810-00194 | 5 | 125 |
| HSN | 810-00230 | 5 | 125 |
| HRN | 810-00227 | 5 | 125 |
| HSB | 810-00237 | 5 | 125 |
| HRB | 810-00239 | 5 | 125 |
Featured Resource:
ZipChip Consumables Guide
Learn how to take the guesswork out of method development with ZipChip. Breeze through your selection in three quick steps.
Additional Resource Downloads:
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