Glycosylation Profiling of mAB Subunits With CZE-MS

This ASMS 2022 poster from Bruker shows ZipChip coupled with high resolution mass spectrometry providing charge-based selectivity which can assist with glycoforms separation.

SDS – ZipChip Interface Tray Grease

SDS – ZipChip Standard: Amino Acids

SDS – ZipChip Acid: Metabolites

SDS – ZipChip BGE: Metabolites

SDS – ZipChip Diluent: Metabolites

EPO Separation & Analysis

Straightforward separation and analysis of a highly glycosylated protein

The Critical Role of CE-MS Methods for Biotherapeutic Characterization

Capillary electrophoresis (CE) methods play an important role in biomolecular characterization while microfluidic CE-mass spectrometry (MS) accelerates analytical workflows and improves development/commercialization timelines.

Microchip CE-MS with Integrated Solid Phase Extraction

Quick screening of intact antibody and antibody drug conjugates with integrated microfluidic capillary electrophoresis and mass spectrometry

This application note shows a method for rapid screening of the heterogeneity of monoclonal antibodies and antibody drug conjugates by an integrated microfluidic capillary electrophoresis (CE) and mass spectrometry (MS) workflow.

A ZipChip Based CZE-MS Analysis for Quick Assessment of Biotherapeutics

From comprehensive characterization to monitoring product degradation characteristics

email Subscribe to Our Communications Signup to receive new product updates, technical tips and more.

Subscribe