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The document discusses the challenges of identifying toxic gases, particularly due to interference from atmospheric components like water vapor and carbon dioxide, which are prevalent in the environment and can obscure spectral data. Traditional FT-IR methods struggle with these interferences, but the XplorIR® handheld device overcomes this limitation through advanced data processing algorithms, including Adaptive Atmospheric Correction and Intelligent Subspace Scaling. These techniques allow XplorIR to accurately identify toxic gases at low concentrations, even in the presence of water vapor and CO2, with high confidence levels. The device can identify a wide range of gases, including ammonia, sulfur dioxide, and hydrogen cyanide, with exceptional accuracy at operationally relevant concentrations. Extensive testing confirms the XplorIR’s ability to detect gases reliably, with minimal false negatives and no false positives, making it a crucial tool for emergency responders. Overall, XplorIR enhances the safety and efficiency of hazardous material detection in the field.
[post_title] => Infrared Gas Identification in Any Condition: Adaptive Atmospheric Correction of the XplorIR
[post_excerpt] => Learn how XplorIR achieves accurate gas sample identification.
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In emergency response and hazmat situations, it's important to distinguish between a device's "limit of detection" (LOD) and "limit of identification" (LOI), as these terms refer to different performance metrics. While LOD indicates the lowest concentration at which a device can detect the presence of a substance, LOI refers to the lowest concentration at which a device can accurately identify a chemical by matching it to reference data. Factors like the signal-to-noise ratio (SNR), operational conditions, and the chemical properties of the substance affect the LOI. The XplorIR®, for example, uses Fourier transform infrared (FTIR) spectroscopy and has two operational modes—Point Mode and Continuous Mode—both optimized for field conditions. LOI values are typically higher than LOD values and depend on factors such as humidity and the presence of interferents like CO2 or water vapor. Ultimately, understanding these metrics, including how mixed products and field conditions impact identification, is crucial for responders when evaluating device performance.
[post_title] => Understanding Limits of Identification of the XplorIR
[post_excerpt] => XplorIR's Limit of Identification can be determined for a given meter and chemical product under specific operational conditions.
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The MX908™ handheld high-pressure mass spectrometer is a cutting-edge device designed for effective threat detection across a wide range of target materials, including explosives, chemical warfare agents (CWAs), and drugs of abuse. It features a fast-switching dual-polarity ionization source and swappable front-end modules, enabling both real-time vapor monitoring at low ppb levels and thermal desorption of solid and liquid samples at nanogram levels. The instrument operates at higher pressures, eliminating the need for bulky, power-hungry vacuum pumps, and provides rapid sample-to-result times of about 30 seconds. Specialized mission modes, such as CW Hunter and Drug Hunter, optimize the device for detecting specific threats with high sensitivity and accuracy. The MX908 offers trace detection in both vapor and thermal desorption modes, with limits of detection in the low ppb and nanogram ranges, making it a versatile and efficient tool for real-time threat analysis.
[post_title] => Multi-Mission Threat Detection with Handheld HPMS
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The document discusses the development of a handheld high-pressure mass spectrometry (HPMS) platform, specifically the MX908, designed for use in field applications by military, law enforcement, and first responders. The device uses a fast-switching dual-polarity APCI (Atmospheric Pressure Chemical Ionization) source, enabling it to perform trace detection in both vapor and thermal desorption modes, with detection limits down to parts-per-billion (ppbv) in vapor mode and nanogram levels on swabs. The MX908 can analyze a wide range of threats, including explosives, narcotics, chemical warfare agents, and relevant precursors, all from a single sample. Its ability to operate at higher pressures (up to 10 Torr) eliminates the need for costly and bulky vacuum pumps, making it more portable and power-efficient. The system is capable of rapid analysis with a broad mass range (m/z ~50-550) and can detect multiple targets without switching samples or polarities. Key applications include the detection of drugs, explosives like PETN and RDX, and toxic chemicals such as sarin and VX, with further refinement and field testing underway.
[post_title] => Next-Generation Handheld High-Pressure Mass Spectrometry
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This work explores the use of a handheld mass spectrometer for detecting fentanyl and its analogs, with a focus on optimizing in-source CID (collision-induced dissociation) for high sensitivity and selectivity, even in the presence of cutting agents. The system employs a low-pressure ion trap, dual-polarity corona discharge ionization, and thermal desorption for real-time vapor analysis, enabling detection of low-volatility substances like opioids. The study demonstrates that the system provides nanogram sensitivity, strong selectivity, and the ability to identify unknown fentanyl analogs through predictive fragmentation patterns. Additionally, the system showed superior performance compared to traditional optical methods in the analysis of contaminated fentanyl samples, achieving detection limits in the sub-100 ng range. The algorithm used in the mass spectrometer effectively identifies a wide range of fentanyl analogs based on mass spectral dissociation patterns. Overall, the handheld device proves to be a versatile tool for opioid detection and other applications.
[post_title] => Analysis of Fentanyl and Its Analogs with a Handheld API Mass Spectrometer and In-Source CID
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The Aero attachment for the MX908 is designed for aerosol detection and identification, including chemical warfare agents and fentanyl analogs, by analyzing both vapor-phase and aerosolized particles. It captures particulate matter on a screen, which is then flash-heated for analysis by a miniaturized mass spectrometer, similar to thermal desorption techniques. The system is capable of trapping more than 80% of particles larger than 2.5 microns in diameter, ensuring effective detection of aerosols in dynamic, real-world environments. Testing under controlled and field conditions, including exposure to hazardous materials like Novichok nerve agents and fentanyl, demonstrated the Aero’s ability to detect aerosols at concentrations as low as 0.01 mg/m3. This makes the Aero a crucial tool for detecting a wide range of aerosolized threats, with minimal down-time and no need for user intervention.
[post_title] => Aerosol Detection and Identification with MX908
[post_excerpt] => Read this tech note full of field test data to understand how the MX908 with Aero works when detecting aerosolized chemicals.
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The document discusses the challenges of identifying toxic gases, particularly due to interference from atmospheric components like water vapor and carbon dioxide, which are prevalent in the environment and can obscure spectral data. Traditional FT-IR methods struggle with these interferences, but the XplorIR® handheld device overcomes this limitation through advanced data processing algorithms, including Adaptive Atmospheric Correction and Intelligent Subspace Scaling. These techniques allow XplorIR to accurately identify toxic gases at low concentrations, even in the presence of water vapor and CO2, with high confidence levels. The device can identify a wide range of gases, including ammonia, sulfur dioxide, and hydrogen cyanide, with exceptional accuracy at operationally relevant concentrations. Extensive testing confirms the XplorIR’s ability to detect gases reliably, with minimal false negatives and no false positives, making it a crucial tool for emergency responders. Overall, XplorIR enhances the safety and efficiency of hazardous material detection in the field.
[post_title] => Infrared Gas Identification in Any Condition: Adaptive Atmospheric Correction of the XplorIR
[post_excerpt] => Learn how XplorIR achieves accurate gas sample identification.
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Tech Notes
Infrared Gas Identification in Any Condition: Adaptive Atmospheric Correction of the XplorIR
Learn how XplorIR achieves accurate gas sample identification.
Understanding Limits of Identification of the XplorIR
XplorIR’s Limit of Identification can be determined for a given meter and chemical product under specific operational conditions.
Multi-Mission Threat Detection with Handheld HPMS
Download this tech note to learn more about how MX908 utilizes high pressure mass spec.
Next-Generation Handheld High-Pressure Mass Spectrometry
Download tech note 1.0 to learn about MX908 with APCI Dual-Polarity Source for Threat Detection and Identification.
Analysis of Fentanyl and Its Analogs with a Handheld API Mass Spectrometer and In-Source CID
In this work we report on the results of optimization of an insource CID sequence and subsequent characterization of the handheld API mass spectrometer/algorithm performance for the analysis of both neat and heavily cut samples containing various fentanyl analogs.
Aerosol Detection and Identification with MX908
Read this tech note full of field test data to understand how the MX908 with Aero works when detecting aerosolized chemicals.
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Nitazenes are a newly emerging class of synthetic opioids that pose a severe and growing threat due to their extreme potency—some variants are up to 40 times stronger than fentanyl. This whitepaper explores the global rise of nitazenes, their impact on overdose rates, challenges in detection, and real-world case studies illustrating their dangers. It also highlights how advanced detection tools like the MX908 are helping first responders and law enforcement identify these substances at trace levels. Essential reading for public health officials, policymakers, and anyone involved in combating the synthetic opioid crisis.
Learn how advanced detection technology like the MX908 is helping law enforcement and first responders identify nitazenes at trace levels—saving lives and fighting back against this rising threat.
[post_title] => The Emerging Threat of Nitazenes in the Synthetic Opioid Crisis
[post_excerpt] => Discover how nitazenes—synthetic opioids up to 40x stronger than fentanyl—are fueling a new wave in the overdose crisis. Learn about detection challenges, real-world case studies, and advanced tools like the MX908 in this essential whitepaper.
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Area monitoring is essential for detecting hazardous materials in the air, ensuring public safety, and enabling timely responses to environmental and health risks. Traditional technologies, such as photoionization detectors and radiation sensors, have been used for decades but are limited in their ability to identify specific toxic threats, particularly chemical warfare agents (CWAs) and pharmaceutical-based agents (PBAs). These traditional systems also struggle with detecting aerosolized threats and provide limited remote monitoring capabilities. The introduction of the MX908 Beacon™ has significantly advanced area monitoring by enabling first responders to detect and identify vapor and aerosol threats, including CWAs and PBAs, in real-time and remotely. The MX908 Beacon allows for extended operational durations and remote data viewing, enhancing the ability to manage hazardous material incidents safely and effectively. This innovation bridges critical gaps in traditional monitoring technologies, improving public safety and responder capabilities in hazardous environments.
[post_title] => White Paper: Area Monitoring for Chemical Warfare and Pharmaceutical Based Agents
[post_excerpt] => Learn more about area monitoring and how MX908 Beacon is the only area monitor on the market to identify chemical warfare agents, etc.
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[post_date] => 2024-02-26 15:19:42
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The MX908 is a rapid and reliable handheld device used by law enforcement to detect drugs of abuse, including trace levels in mixtures with cutting agents, which are common in street drugs. It has a low false alarm rate of 1.4%, and with additional Reachback analysis, the rate drops to 0%. The device leverages high-pressure mass spectrometry to identify substances with minimal interference from cutting agents, which can often cause false positives or negatives in other field tests like colorimetric kits. The testing demonstrated that the MX908 effectively distinguishes between controlled substances and common cutting agents, even in low concentrations. Additionally, the raw data collected by the device can be reviewed by forensic chemists to further confirm results, making it a valuable tool for law enforcement in the field.
[post_title] => The MX908 Advantage in the Presence of Cutting Agents
[post_excerpt] => Read our latest whitepaper to see how MX908 performed in a study of the most common cutting agents found around the world and, when combined with Reachback analysis, improved the false positive rate from <2%, to 0%.
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[post_date] => 2022-11-08 10:11:33
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[post_content] =>
Despite the global trend of marijuana legalization, the illegal marijuana market continues to thrive, with criminal operations becoming more efficient. Many illegal growers are setting up “trespass grows” on public lands, bypassing regulations that ensure consumer safety and causing severe environmental damage. These grow operations often involve the use of toxic pesticides that harm wildlife, contaminate water supplies, and pose health risks to law enforcement and cleanup workers. In the U.S., the Forest Service has dismantled over 1,000 grow sites between 2017 and 2020, finding significant amounts of trash, hazardous chemicals, and illegal pesticides. Traditional detection methods for these chemicals, like colorimetric tests or lab-based mass spectrometry, are either imprecise or slow. To address this, the MX908 handheld mass spectrometer was developed, allowing for rapid and accurate identification of pesticides at illegal grow sites, enabling safer and more efficient cleanup operations.
[post_title] => White Paper: Pesticide Detection and Identification at Illegal Marijuana Grows
[post_excerpt] => With pesticides posing an imminent danger for wildlife in the area, responding law enforcement also find themselves potentially exposed to the hazardous chemicals
[post_status] => publish
[comment_status] => closed
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[post_date] => 2021-10-14 08:34:05
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The MX908 is a handheld chemical detection tool that uses high-pressure mass spectrometry to quickly and accurately identify unknown substances, making it invaluable for law enforcement and prosecutors. It helps identify controlled substances like fentanyl, methamphetamine, and cocaine in the field, enhancing officer safety by reducing exposure to toxic materials. The device analyzes trace amounts of substances, including residue on packaging, to identify narcotics without opening potentially dangerous containers. The MX908 supports law enforcement investigations by providing presumptive evidence for arrests, search warrants, and court proceedings, while reducing lab backlogs and conserving resources. Its results are widely accepted in court, and proper training and procedural documentation ensure the reliability and admissibility of test results.
[post_title] => Using MX908 in Investigations and Court
[post_excerpt] => Users can conduct field analysis of unknown substances at trace levels to generate actionable intelligence in real time to assess threat levels, establish probable cause, and prioritize investigatory resources accordingly, all while reducing operator exposure.
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[post_date] => 2017-11-28 16:48:55
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Hazardous materials response teams often face high-pressure situations where they must quickly gather actionable information about chemical incidents, especially in high-profile settings like buildings with multiple illnesses. Initial reconnaissance (recon) efforts, using tools like multi-gas meters and photoionization detectors (PIDs), help identify potential hazards but often lack the sensitivity and specificity needed for decisive action. In these scenarios, high-pressure mass spectrometry (HPMS) technology offers a significant advantage by providing rapid, reliable chemical detection with high certainty. HPMS devices can identify chemical agents in just seconds, allowing responders to make quick, informed decisions regarding safety and medical treatment. Additionally, HPMS can switch between vapor and trace modes for on-site analysis, reducing the need for multiple surveys and speeding up the response process. This portable, fast, and accurate technology enhances the ability of response teams to effectively address chemical threats in various emergency situations.
[post_title] => Actionable Information from High Pressure Mass Spectrometry
[post_excerpt] => The detection and identification of chemicals with HPMS carries sufficient information to warrant definitive action, medical treatment and communication.
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The MX908 is a field identification tool that provides rapid, accurate, and reliable analysis of controlled substances, making it an essential tool for law enforcement. Powered by high-pressure mass spectrometry, it enables officers to quickly identify substances with minimal user interpretation and without exposure to toxic materials like synthetic opioids. The device can analyze trace amounts of drugs, including fentanyl and carfentanil, that other methods often miss. Its results can establish probable cause for warrants, facilitate plea deals, and expedite cases by providing immediate feedback, reducing reliance on slow lab results. The MX908 is admissible in court under Federal Laws of Evidence and has been proven reliable by multiple independent agencies, supporting its use in criminal investigations.
[post_title] => Trace Detection in the Field Expedites Prosecution
[post_excerpt] => Mass spectrometry is classified as a Category A technique by the Scientific Working Group on Seized Drug Analysis (SWGDRG) and ASTM 2329-17 and has been admissible in court for more than 50 years. Download to read more.
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[post_date] => 2021-05-07 19:34:02
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Emergency responders face unique challenges when selecting personal protective equipment (PPE) and responding to hazardous materials, especially aerosols. Aerosols, which consist of solid or liquid particles suspended in the air, behave like gases but retain the properties of solids or liquids. These particles pose significant risks due to their ability to remain airborne and be inhaled, potentially leading to severe health hazards. Traditional detection methods struggle to identify aerosolized chemicals, as they typically require substances to be in solid, liquid, or gas form. Recent advancements, such as the MX908® with the Aero module, allow responders to detect and identify aerosolized threats in real-time, improving safety and response effectiveness. This technology helps manage the complexities of aerosol hazards by providing accurate, on-site identification of airborne chemical threats, including toxic materials like fentanyl and chemical warfare agents.
[post_title] => Aerosol Hazard Management 101
[post_excerpt] => Read this white paper to learn more about the hazard posed by aerosolized chemicals. You will learn about aerosols and their properties and how to successfully address them in the field.
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The poisoning of Sergei and Yulia Skripal in 2019 highlighted the global concerns about Fourth Generation Agents (FGAs), such as the Novichok series, which are highly toxic chemical agents. This document provides guidance for first responders on detecting, identifying, decontaminating, and destroying these agents using commercially available technologies. FGAs pose serious health risks, primarily through dermal exposure, but can also be absorbed via inhalation or ingestion. Detection technologies like Raman, FTIR, and colorimetric methods are inadequate for FGAs due to their high limits of detection. The MX908 from 908 Devices is the only portable device capable of identifying trace levels of A-series agents with high sensitivity. For decontamination, a hybrid approach is recommended, combining Fibertect wipes, Reactive Skin Decontamination Lotion (RSDL), and Dahlgren Decon, along with the use of detection devices to ensure complete removal of the threat.
[post_title] => Operational Response to Fourth Generation Agents
[post_excerpt] => Read this whitepaper written by Christina Baxter Ph.D., to prepare responders with commercially available solutions to detect, identify, decontaminate, destroy, and confirm the destruction of the A-series agents.
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Trace detection of hazardous materials, especially in light of the opioid epidemic and emerging threats like Novichoks, requires highly sensitive and reliable tools to detect both "invisible" (extremely small quantities) and "hidden" (small amounts mixed with larger, non-hazardous substances) threats. Current detection methods, such as ion mobility spectrometry (IMS), gas chromatography-mass spectrometry (GCMS), and optical techniques, face limitations in sensitivity, specificity, and operational efficiency. High-pressure mass spectrometry (HPMS), particularly the MX908 device, overcomes these limitations by offering both high sensitivity and fidelity, capable of detecting substances at concentrations as low as 20 nanograms. The HPMS's ability to generate mass spectral images allows for accurate identification and differentiation of chemicals, even in complex mixtures, and it can detect novel chemical threats using predictive algorithms. The MX908 combines the benefits of both trace and bulk detection, providing a powerful tool for emergency responders to handle the increasing variety of chemical hazards confidently and quickly.
[post_title] => A New Approach to Trace Detection
[post_excerpt] => Today’s emergency responders and security personnel need detection capabilities which address both categories with high sensitivity (the ability to detect threat materials below harmful levels) and high fidelity (the ability to detect reproducibly and reliably).
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Nitazenes are a newly emerging class of synthetic opioids that pose a severe and growing threat due to their extreme potency—some variants are up to 40 times stronger than fentanyl. This whitepaper explores the global rise of nitazenes, their impact on overdose rates, challenges in detection, and real-world case studies illustrating their dangers. It also highlights how advanced detection tools like the MX908 are helping first responders and law enforcement identify these substances at trace levels. Essential reading for public health officials, policymakers, and anyone involved in combating the synthetic opioid crisis.
Learn how advanced detection technology like the MX908 is helping law enforcement and first responders identify nitazenes at trace levels—saving lives and fighting back against this rising threat.
[post_title] => The Emerging Threat of Nitazenes in the Synthetic Opioid Crisis
[post_excerpt] => Discover how nitazenes—synthetic opioids up to 40x stronger than fentanyl—are fueling a new wave in the overdose crisis. Learn about detection challenges, real-world case studies, and advanced tools like the MX908 in this essential whitepaper.
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White Papers
The Emerging Threat of Nitazenes in the Synthetic Opioid Crisis
Discover how nitazenes—synthetic opioids up to 40x stronger than fentanyl—are fueling a new wave in the overdose crisis. Learn about detection challenges, real-world case studies, and advanced tools like the MX908 in this essential whitepaper.
White Paper: Area Monitoring for Chemical Warfare and Pharmaceutical Based Agents
Learn more about area monitoring and how MX908 Beacon is the only area monitor on the market to identify chemical warfare agents, etc.
The MX908 Advantage in the Presence of Cutting Agents
Read our latest whitepaper to see how MX908 performed in a study of the most common cutting agents found around the world and, when combined with Reachback analysis, improved the false positive rate from <2%, to 0%.
White Paper: Pesticide Detection and Identification at Illegal Marijuana Grows
With pesticides posing an imminent danger for wildlife in the area, responding law enforcement also find themselves potentially exposed to the hazardous chemicals
Using MX908 in Investigations and Court
Users can conduct field analysis of unknown substances at trace levels to generate actionable intelligence in real time to assess threat levels, establish probable cause, and prioritize investigatory resources accordingly, all while reducing operator exposure.
Actionable Information from High Pressure Mass Spectrometry
The detection and identification of chemicals with HPMS carries sufficient information to warrant definitive action, medical treatment and communication.
Trace Detection in the Field Expedites Prosecution
Mass spectrometry is classified as a Category A technique by the Scientific Working Group on Seized Drug Analysis (SWGDRG) and ASTM 2329-17 and has been admissible in court for more than 50 years. Download to read more.
Aerosol Hazard Management 101
Read this white paper to learn more about the hazard posed by aerosolized chemicals. You will learn about aerosols and their properties and how to successfully address them in the field.
Operational Response to Fourth Generation Agents
Read this whitepaper written by Christina Baxter Ph.D., to prepare responders with commercially available solutions to detect, identify, decontaminate, destroy, and confirm the destruction of the A-series agents.
A New Approach to Trace Detection
Today’s emergency responders and security personnel need detection capabilities which address both categories with high sensitivity (the ability to detect threat materials below harmful levels) and high fidelity (the ability to detect reproducibly and reliably).
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