Cell Culture Media Analyzer


At-line cell culture media analysis. Results on 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.

Easy to understand answers
No more waiting for third party testing
Accurate, reliable performance whether running 1 or 100 samples

Get out of line. Waiting weeks for cell culture media analysis is optional. Get at-line media analysis for 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.

Trusted by BioPharma

Listen to how scientists have put REBEL and ZipChip to use in speeding up their research.

Blast Off

Shave weeks or even months off your process development cycles. All you need to run the REBEL cell culture analyzer is you. No core lab, no analytical support teams, no sending samples out and waiting weeks for results. Set it up right next to your bioreactors and get quantitative data for amino acids, dipeptides, water soluble vitamins and biogenic amines in 10 minutes or less. Combine that with your other standard metabolites and make decisions ASAP.

Take Charge

Getting results is drama-free. Pull a bioreactor sample, spin it down, and dilute. Load into the REBEL and hit start. Run samples solo or in 96-well plates if you’re on a roll.

There’s no messing around with settings or data analysis either. Reports kick out automatically and upload to your network drive. 

Download Samples:

Blow Past Bottlenecks

Upstream process scientists analyzing bioreactor samples. Media design groups optimizing chemically-defined medium formulations. Analytical teams supporting multiple groups. The REBEL cell culture analyzer removes analytical bottlenecks across the board.

1. Pull A Sample

Pull a sample from your bioreactor, shake flask or well plate. The Rebel only needs 10µL.

2. Spin and Dilute

Spin out your cells and dilute. That’s as complicated as it gets.

3. Load Your Samples

Load your samples, reagents and calibrants.

4. Generate Results

Hit start, get results. Results can quickly be reviewed in a simple report.

Remove Data Analysis Bottlenecks

REBEL users with access to the JMP statistical software package are able to expedite high-throughput data analysis by REBEL data visualization. REBEL users can download the add-in tool from the 908 Devices customer support portal. To learn more about the REBEL and the visualization tool, watch the BPI: Ask the Expert Webinar, and click the button to obtain a JMP software trial.

Consumables That Don’t Consume Your Time

Easy Sample

Just filter, spin, and dilute your samples. There’s no chemical reaction, and it works for both low and high sample throughput needs

Low-Effort Method Development

Use the touch screen to get the sample running. BGE carries the samples through the microchip for ESI-MS detection

Simple System

The REBEL makes it easy with a built-in quantification calibration and system performance check with REBEL SMA standard


30+ analytes including amino acids, vitamins, and amines are quantified in as little as 10 minutes per sample

How Will You Use REBEL?

Monitor amino acids and vitamins throughout your bioreactor time course. Refine feeding strategies on the fly. Correlate media selection to product quality and yield.

What’s On The Menu:

Amino Acids

  • Alanine
  • Alanyl-Glutamine
  • Arginine
  • Asparagine
  • Aspartic acid
  • Betaine
  • Cystine
  • Glutamic acid
  • Glutamine
  • Glycine
  • Histidine
  • Isoleucine
  • Leucine
  • Lysine
  • Methionine
  • Phenylalanine
  • Proline
  • Serine
  • Threonine
  • Tryptophan
  • Tyrosine
  • Valine

Biogenic Amines

  • GABA
  • Beta-Alanine
  • Hydroxyproline
  • Methyl-L-histidine
  • L-Citrulline
  • Sarcosine


  • Choline
  • Nicotinamide
  • Pyridoxal
  • Pyridoxine
  • Thiamine

Customer Support Portal

The My 908 portal gives scientists quick access to important resources like the latest software upgrades, product guides, and training materials.

Frequently Asked Questions

How do I load samples and queue up a run on the REBEL?

The REBEL accepts both septa capped vials and 96-well plates. We provide two plates with each consumable kit. The REBEL’s autosampler is cooled to 5 °C, and there are plate covers included in the kits to prevent evaporation. Once your samples are loaded, you can manually input your sample information using the REBEL’s intuitive user interface and touchscreen or import a CSV template file that you have already prefilled. The template expedites the process if you are loading a full plate of samples, and we provide the template to you during installation.

What data formats does the REBEL export, and how are the files saved?

The REBEL saves processed reports in either CSV or PDF file formats. When configured for network storage, the files are saved in real time. No permanent storage of data files or reports is ensured on the REBEL if saved on the internal storage system. It is expected that your company’s corporate IT policies can be employed for the resulting files deposited on network shares for long term retention, fraud prevention and adulteration.

How does the REBEL fit alongside my current workflows?

In a typical process development or cell culture lab, the REBEL fits along with all your other process analytics like a cell viability and general biochemical analyzers. By implementing the REBEL in the same lab as your other gear, you can eliminate the need to send out your samples to a core lab, saving a significant amount of time. Gaining near-real time analytics on an extended list of analytes and nutrients in your bioreactors and fermenters allows you to improve your efficiency in the lab instead of waiting weeks for your data.

email Subscribe to Our Communications Signup to receive new product updates, technical tips and more.