Multi-omic Analyses Enabled by Microchip Capillary Electrophoresis and Trapped Ion Mobility Mass Spectrometry

Microchip capillary electrophoresis coupled to trapped ion mobility mass spectrometry promises high “omic” coverage in an impressively short time and minimal sample preparation. This poster was presented as a collaboration with the University of Wisconsin-Madision at ASMS 2023 as poster THP248.

Exploring the Possibilities for Microchip SPE-CE-MS

Integrated SPE-CE-MS is working well using C18 particles for bottom-up proteomics. What else can we do with this new platform? This poster was presented at ASMS 2023 as poster MP550.

ZipChip Customer Experience: NIBRT – 908 Devices Exceeds in Support

Dr. Josh Smith from NIBRT discusses the incredible customer support he receives from 908 Devices.

ZipChip Customer Experience: University of Wisconsin – Fast ZipChip Separations

Zicong Wang, a graduate student discusses how fast ZipChip separations increase his workflow in only 20 minutes compared to other LC-MS methods.

ZipChip Customer Experience: University of Wisconsin – ZipChip is easy to use

Ying Ge from the University of Wisconsin discusses how easy ZipChip is to use in proteomics.

Multi-omic Analyses Enabled by Microchip Capillary Electrophoresis and Trapped Ion Mobility Mass Spectrometry

Microchip capillary electrophoresis coupled to a trapped ion mobility mass spectrometry promises high “omic” coverage in impressively short time and with minimal sample preparation.

Interview: The Unprecedented Potential of CE-MS for Proteomics

Recorded at ASMS 2022, Michael MacCoss from the University of Washington and Will Thompson from 908 Devices discuss how ZipChip is addressing key challenges in proteomics, and its potential in diagnostics, investigating bacterial proteomes, and metabolite analysis.

Combining μSPE ZipChip CE with PRM-LIVE on a timsTOF Pro for Warp-speed Selectivity Profiling of Deubiquitinase (DUB) Small Molecule Inhibitors

In this ASMS 2022 poster, researchers from Dana Farber Cancer Institute and Harvard Medical School developed a ZipChip-based method for facilitating high-throughput identification
of new small molecule inhibitors.

Pushing the Boundaries of Speed and Sensitivity in Proteomics

To overcome sample loading limitations in CE-MS, the poster authors engineered a 1 mm SPE bed within the chip geometry, allowing 100-fold improvements in concentration sensitivity limit for CE-MS.

Characterization of a SRPK1/2 Inhibitor Complex

Characterizing Covalent CDK Inhibitor Complexes

Identification of AAV capsid proteins

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