Combining μSPE ZipChip CE with PRM-LIVE on a timsTOF Pro for Warp-speed Selectivity Profiling of Deubiquitinase (DUB) Small Molecule Inhibitors
In this ASMS 2022 poster, researchers from Dana Farber Cancer Institute and Harvard Medical School developed a ZipChip-based method for facilitating high-throughput identification
of new small molecule inhibitors.
Pushing the Boundaries of Speed and Sensitivity in Proteomics
To overcome sample loading limitations in CE-MS, the poster authors engineered a 1 mm SPE bed within the chip geometry, allowing 100-fold improvements in concentration sensitivity limit for CE-MS.
Characterization of a SRPK1/2 Inhibitor Complex
Characterizing Covalent CDK Inhibitor Complexes
Identification of AAV capsid proteins
ZipChip Platform Brochure
Download our platform brochure to learn how ZipChip® platform prepares and separates a wide range of biological samples, then electrosprays them into your mass spec for analysis.
Analysis of inhibitor-protein complexes and small molecules
ZipChip for Glycomics and Glycoproteomics
Combined Top-down and Bottom-up Proteomics
Analysis of monosaccharides, oligosaccharides and glycopeptides
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