Interview: The Unprecedented Potential of CE-MS for Proteomics

Recorded at ASMS 2022, Michael MacCoss from the University of Washington and Will Thompson from 908 Devices discuss how ZipChip is addressing key challenges in proteomics, and its potential in diagnostics, investigating bacterial proteomes, and metabolite analysis.

Combining μSPE ZipChip CE with PRM-LIVE on a timsTOF Pro for Warp-speed Selectivity Profiling of Deubiquitinase (DUB) Small Molecule Inhibitors

In this ASMS 2022 poster, researchers from Dana Farber Cancer Institute and Harvard Medical School developed a ZipChip-based method for facilitating high-throughput identification
of new small molecule inhibitors.

Pushing the Boundaries of Speed and Sensitivity in Proteomics

To overcome sample loading limitations in CE-MS, the poster authors engineered a 1 mm SPE bed within the chip geometry, allowing 100-fold improvements in concentration sensitivity limit for CE-MS.

Characterization of a SRPK1/2 Inhibitor Complex

Characterizing Covalent CDK Inhibitor Complexes

Identification of AAV capsid proteins

ZipChip Platform Brochure

Download our platform brochure to learn how ZipChip® platform prepares and separates a wide range of biological samples, then electrosprays them into your mass spec for analysis.

Analysis of inhibitor-protein complexes and small molecules

ZipChip for Glycomics and Glycoproteomics

Combined Top-down and Bottom-up Proteomics

Analysis of monosaccharides, oligosaccharides and glycopeptides

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